04 October 2021
Contact: Kawana McGough, Office of Communications, Public Relations and Marketing
Dr Clayton Yates, professor of biology and director of the university’s Multidisciplinary Center for Biomedical Research, won the 2021 Movember-Prostate Cancer Foundation (PCF) Challenge Award to support pioneering interdisciplinary research aimed at finding cures for cancer of prostate. The prize, totaling $ 2 million, is presented to teams from some of the world’s leading cancer research institutions.
As part of the award, Yates will be the lead researcher in creating a digital health tool that will increase ethnic and racial diversity in prostate cancer clinical trials and develop a training program to increase the number of minorities under-represented in computer research on disparities in prostate cancer. .
The “MET-PAAM: Elucidating the Molecular Mechanisms of Tumor Progression in Metastatic Prostate Cancer Among Men of African Ancestry” project will map the landscape of genomic alterations in African-American prostate cancers, which will allow the development of new approaches to medicine. precision.
âAfrican American patients show significant disparities in the diagnosis and outcome of prostate cancer compared to Caucasian patients. This research will better understand genomic alterations in African American men with hormone-sensitive metastatic PCa (mHSPC) and castration-resistant (mCRPC) at the single-cell level, âYates explained. “Additionally, this grant will support the expansion of our existing training program at the Center for Biomedical Research, which aims to provide students from under-represented minorities (URMs) with the opportunity to become scientific leaders in computational genomics and PCa disparities.” . “
âResearch from previous Challenge Awards has led to many important findings that improve outcomes for men with prostate cancer,â said Jane Fisher, Ph.D., Global Director of Research on cancer and clinical trials of Movember.
In addition, Franklin Huang, MD, Ph.D., University of California, San Francisco; San Francisco Veterans Medical Center and Elisabeth Heath, MD, Karmanos Cancer Institute; Wayne State University will also serve as principal investigators.
âThe PCF Challenge Award aims to support an ambitious scientific team with the potential to develop new treatments for metastatic prostate cancer,â said PCF Executive Vice President and Scientific Director Howard R. Soule, Ph.D . “We commend Drs Huang, Heath, Yates and Freedman and their colleagues for their research which we believe has the potential to develop new therapeutic approaches for advanced prostate cancer and provide more options for patients. in need.”
About the Prostate Cancer Foundation
The Prostate Cancer Foundation (PCF) is the world’s leading philanthropic organization dedicated to funding vital prostate cancer research. Founded in 1993 by Mike Milken, PCF has nearly $ 1 billion to support cutting-edge research through more than 2,200 research projects in 220 leading cancer centers in 22 countries around the world. Thanks in part to the PCF’s commitment to end the death and suffering of prostate cancer, the death rate has fallen by 52%, and countless more men are alive today. Research from the Prostate Cancer Foundation is now impacting more than 70 forms of human cancer by focusing on immunotherapy, the microbiome, and diet as medicine. Learn more about www.pcf.org.
Movember is the leading charity changing the face of men’s health globally, focusing on mental health and the prevention of suicide, prostate cancer and testicular cancer. The charity raises funds to deliver innovative and groundbreaking research and support programs that empower men to live happier, healthier, and longer lives. Committed to disrupting the status quo, millions of people have joined the movement, helping fund more than 1,250 projects around the world.
In addition to tackling the major health issues facing men, Movember strives to encourage men to stay healthy in all areas of their lives, with a focus on men who stay socially connected and become more open to discussing their health and important moments in their lives. The charity’s vision is to have an everlasting impact on the face of men’s health. To donate or learn more, please visit Movember.com.
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