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HKUMed research team combines artificial intelligence and protein engineering technology to improve gene editing efficiency

A research team from the University of Hong Kong’s LKS School of Medicine (HKUMed) has discovered more efficient CRISPR-Cas9 variants that could be useful for gene therapy applications. By establishing a new pipeline methodology that implements machine learning on high-throughput screening to accurately predict the activity of protein variants, the team expands the ability to analyze up to 20 times more variants at time without the need to acquire additional experimental data, which dramatically accelerates the speed of protein engineering. The research team successfully applied the pipeline in several Cas9 optimizations and engineered novel Staphylococcus aureus Cas9 (SaCas9) variants with improved gene-editing efficiency. The results are now published in Nature Communications (link to publication) and a patent application has been filed based on this work.

Background

Staphylococcus aureus Cas9 (SaCas9) is an excellent candidate for in vivo gene therapy due to its small size allowing packaging into adeno-associated viral vectors to be delivered into human cells for therapeutic applications. However, its gene editing activity might be insufficient for some specific disease loci. Further optimizations of SaCas9 are crucial in precision medicine before it can be used as a reliable tool to treat human diseases. These optimizations consist of increasing its efficiency and accuracy by modifying the Cas9 protein. The standard protocol for modifying the protein involves saturation mutagenesis, where the number of possible modifications that could be introduced into the protein far exceeds the experimental screening capacity of even state-of-the-art high-throughput platforms by orders of magnitude.

In this work, the research team explored whether the combination of machine learning with structure-guided mutagenesis library screening could enable virtual screening of many other modifications to accurately identify rare and top-performing variants. for further validation.

search results

The research team tested the machine learning framework on several previously published mutagenesis screens on Cas9 variants and illustrated that machine learning could robustly identify the best performing variants using only 5-20% of the experimentally determined data.

The Cas9 protein contains several parts, including protospacer-adjacent (PAM) (PI) and Wedge (WED) motif-interacting domains to facilitate its interaction with the target DNA duplex. The research team coupled the platforms of machine learning and high-throughput screening to design an enhanced activity SaCas9 protein by combining mutations in its PI and WED domains surrounding the DNA duplex carrying a (PAM) . PAM is essential for Cas9 to modify the target DNA and the idea was to reduce the PAM constraint for broader genome targeting while securing the protein structure by enhancing the interaction with the PAM-containing DNA duplex via the domain WED.

In the screen and subsequent validations, the researchers identified new variants, including one named KKH-SaCas9-plus, with up to 33% improved activity at specific genomic loci. The subsequent protein modeling analysis revealed the new interactions created between the WED and PI domains at several locations in the PAM-containing DNA duplex, attributing to the increased efficiency of KKH-SaCas9-plus.

Importance of research

Structure-guided design dominates the field of Cas9 engineering; however, it only explores a small number of sites, amino acid residues, and combinations. In this study, the research team showed that screening on a larger scale and with less experimental effort, time and cost can be performed using the multi-domain combinatorial mutagenesis screening approach. coupled with machine learning, which led them to identify a novel high-efficiency variant KKH-SaCas9-plus.

“This approach will significantly accelerate the optimization of Cas9 proteins, which could allow genome editing to be applied to the treatment of genetic diseases more efficiently,” said Dr. Alan Wong Siu-lun, assistant professor at the School of Biomedical Sciences, HKUMed.

About the research team

This research was led by Dr. Alan Wong Siu-lun, Assistant Professor, School of Biomedical Sciences, HKUMed, as corresponding author. Ms. Dawn Thean Gek-lian, research assistant; Dr. Athena Chu Hoi-yee, Postdoctoral Fellow, School of Biomedical Sciences, HKUMed, were co-first authors, with assistance from Dr. Fong Hoi-chun, PhD student; Mrs. Becky Chan Ka-ching, doctoral student; Dr. Zhou Peng, postdoctoral fellow; Ms. Cynthia Kwok Chui-shan, Research Assistant, and Dr. Gigi Choi Ching-gee, Postdoctoral Fellow, School of Biomedical Sciences, HKUMed. Other collaborators included Dr. Joshua Ho Wing-kei, Associate Professor, School of Biomedical Sciences, HKUMed; Dr. Zheng Zongli and his team from Ming Wai Lau Center for Restorative Medicine, Karolinska Institutet, Hong Kong Node.

Acknowledgement

This work was supported by the Excellent Young Scientists Fund, the National Natural Science Foundation of China (32022089), the Hong Kong Research Grants Council (17104619) and the Center for Oncology and Immunology Limited under the [email protected] Program initiated by the Innovation and Technology Commission, Hong Kong Special Administrative Region (HKSAR) government. This work was also supported in part by the Associate Member Program of the Ming Wai Lau Center for Reparative Medicine and the [email protected] launched by the Innovation and Technology Commission, HKSAR Government.

Rabies Diagnostics Market Size, Scope and Forecast

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New Jersey, United States – This Rabies diagnostics market the research examines the status and future prospects of the Rabies Diagnostics market from the perspective of competitors, regions, products and end-use applications/industry. The global rabies diagnostics market is segmented by products and applications/end industries in this analysis, which also analyzes the various players in global and key regions.

The Rabies Diagnostics market analysis is included in this report in its entirety. Extensive secondary research, primary interviews, and internal expert reviews have been incorporated into the Rabies Diagnostics report market estimations. These market estimations have been considered by researching the effects of different social, political, and economic aspects, as well as current market dynamics, on the growth of the Rabies Diagnostics market.

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Key Players Mentioned in the Rabies Diagnostics Market Research Report:

Merck KGaA, Bio-Rad Laboratories Aviva Systems Biology Corporation, Norgen Biotek Corp., Demeditec Diagnostics GmbH, Creative Diagnostics, Abbexa Ltd., MyBioSource.com, Express Biotech International Inc., BioNote, Inc.

Porter’s five forces analysis, which explains the five forces: customer bargaining power, distributor bargaining power, threat of substitute products, and degree of competition in the rabies diagnostics market, is included in the report with the market overview, which includes the market dynamics. It describes the various players that make up the market ecosystem, including system integrators, intermediaries, and end users. The competitive environment of the Rabies Diagnostics market is another major topic of the report. For better decision-making, the research also provides in-depth details of the COVID-19 scenario and its influence on the market.

Rabies Diagnostics Market Segmentation:

Rabies Diagnostics Market, By Diagnostic Method

• Fluorescent antibody test (FAT)
• Immunohistochemical test
• Amplification methods
• Histological examination
• Serological tests

Rabies Diagnostics Market, By Technology

• ELISA/Immunohistochemistry
• Chromatography techniques
• PCR
• Others

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Scope of the Rabies Diagnostics Market Report

ATTRIBUTES DETAILS
ESTIMATED YEAR 2022
YEAR OF REFERENCE 2021
FORECAST YEAR 2029
HISTORICAL YEAR 2020
UNITY Value (million USD/billion)
SECTORS COVERED Types, applications, end users, and more.
REPORT COVER Revenue Forecast, Business Ranking, Competitive Landscape, Growth Factors and Trends
BY REGION North America, Europe, Asia-Pacific, Latin America, Middle East and Africa
CUSTOMIZATION SCOPE Free report customization (equivalent to up to 4 analyst business days) with purchase. Added or changed country, region and segment scope.

Answers to key questions in the report:

1. Who are the top five Rabies Diagnostics market players?

2. How will the rabies diagnostics market evolve over the next five years?

3. Which products and applications will capture the lion’s share of the rabies diagnostics market?

4. What are the Rabies Diagnostics Market drivers and restraints?

5. Which regional market will show the strongest growth?

6. What will be the CAGR and size of the Rabies Diagnostics market throughout the forecast period?

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VMI provides a global overview and competitive landscape with respect to region, country and segment, as well as key players in your market. Present your market report and results with an integrated presentation function that saves you more than 70% of your time and resources for presentations to investors, sales and marketing, R&D and product development. products. VMI enables data delivery in Excel and interactive PDF formats with over 15+ key market indicators for your market.

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About Us: Verified Market Research®

Verified Market Research® is a leading global research and advisory firm that for over 10 years has provided advanced analytical research solutions, personalized advice and in-depth data analysis to individuals and businesses seeking accurate research, reliable and up to date. data and technical advice. We provide insight into strategic and growth analytics, the data needed to achieve business goals, and help make critical revenue decisions.

Our research studies help our clients make superior data-driven decisions, understand market forecasts, capitalize on future opportunities, and maximize efficiency by working as a partner to deliver accurate and valuable insights. The industries we cover span a wide spectrum, including technology, chemicals, manufacturing, energy, food and beverage, automotive, robotics, packaging, construction, mining and the gas. Etc.

At Verified Market Research, we help in understanding holistic market indicator factors and most current and future market trends. Our analysts, with their deep expertise in data collection and governance, use industry techniques to gather and review data at all stages. They are trained to combine modern data collection techniques, superior research methodology, subject matter expertise and years of collective experience to produce informative and accurate research.

Having served over 5000 clients, we have provided reliable market research services to over 100 Global Fortune 500 companies such as Amazon, Dell, IBM, Shell, Exxon Mobil, General Electric, Siemens, Microsoft, Sony and Hitachi. We have co-consulted with some of the world’s leading consulting firms such as McKinsey & Company, Boston Consulting Group, Bain and Company for custom research and consulting projects for companies around the world.

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Denver Passes Volume-Based Waste Program in Split Vote, Implementation Begins Jan. 1 | Content reserved for subscribers

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Denver will implement a new fee-based waste management services program in early 2023 after the council passed the program in an 8-5 vote Monday night.

Council members in favor of the program reiterated that there was no time to waste on taking action on climate change, while those who voted against were very concerned about the impacts of an additional fee on the cost of life for the city’s most vulnerable residents, as well as the lack of a strong education campaign.

Some council members said they heard overwhelming comments from constituents demanding weekly recycling, while others said they heard overwhelming comments against the new fee.

The expanded waste management services program will charge residents of single-family homes and small multi-family buildings a monthly fee based on the size of the trash can they need. The pricing structure will charge $9 for a small trash can, $13 for a medium, and $21 for a large. Recycling and composting will be included at no additional cost, with weekly pick-up services in addition to other solid waste services.

Currently, weekly and fortnightly garbage recycling services are funded from the city’s general fund – to which everyone in the city contributes – with an additional charge for composting. Under the new program, residents will pay based on what they send to landfill rather than what they divert. The fees are not intended to generate new revenue, but rather to pay for the cost of the program.

The program will begin Jan. 1, 2023, with a $3 inconvenience credit given to city residents who have yet to set up their composting services in the first half of the year as the city rolls out the program.

The program also includes an affordability program that would provide eligible households with instant rebates on their bills. Eligibility is based on area median income, with households earning 60% of the AMI getting a 50% discount, those earning 50% of the AMI getting a 75% discount, and those earning 30% of the AMI getting a 100% discount.

Council member Jamie Torres said she agreed with a speaker at Council’s courtesy public hearing on Monday evening who said everyone will eventually pay the price, but that this will not be a question of money. It will be about the climate.

Torres said while the costs will be difficult for many to manage, the future without climate action will only be worse. She said she supports the program knowing that the required outreach will be significant, both to educate the public about the program’s operations and to ensure that those who are eligible for instant discounts can easily enroll.

Council member Paul Kashmann said he had a hard time with the bill because while he understands the struggles voters are having with the cost of living, he also sees the news on climate change getting darker and darker every day. He said Denver is a national leader.

“If we go ahead with this bill, people will follow us and our contribution to reducing climate change will be magnified,” Kashmann said. “If we fail to lead, if we fail to act, it will give justification to some people not to act and again we will reduce our efforts to control climate change.”

Council Member Kevin Flynn reiterated that he and his fellow Council Members who vote against the program do so solely on the basis of fees, not the principle of climate action, which Council Chair Stacie Gilmore, also reiterated as a wildlife biologist. Several council members questioned why the Department of Transportation and Infrastructure had never considered providing free composting in an effort to improve diversion rates.

Other dissenting votes came from Council members Candi CdeBaca, Chris Herndon and Deborah Ortega.

“It’s difficult for me tonight to live in America’s most polluted ZIP code which also happens to be one of the most vulnerable to involuntary displacement,” CdeBaca said. “Every fee counts. I don’t want to support an order that makes the most vulnerable an afterthought, as usual.”

The program is rolling out gradually in early 2023 as DOTI continues to work to hire more drivers and hire inspectors to put the program in the best position for success.

Two crucial genes for plants colonizing Earth 470 million ago have been identified

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Scientists think it’s likely that the two genes, PEN1 and SYP122, paved the way for all terrestrial plant life.

Researchers shed new light on how plant life established itself on Earth’s surface

Researchers from the University of Copenhagen have shed new light on how plant life established itself on the surface of our planet. In particular, they demonstrated that two genes are crucial for land plants to protect themselves against fungal attacks – a defense mechanism that dates back 470 million years. These defenses probably paved the way for all terrestrial plant life.

Mads Eggert Nielsen

Mads Eggert Nielsen, biologist at the University of Copenhagen.

Plants evolved from aquatic algae to be able to survive on land about half a billion years ago, laying the foundations for life on earth. Mushrooms were one of the obstacles that made this dramatic transition so difficult:

“It is estimated that 100 million years ago, fungi slithered across the Earth’s surface in search of food and most likely found it in dead algae washed out to sea. So if you , as a new plant, were going to establish yourself on earth and the first thing you encountered was a fungus that would eat you, you needed some sort of defense mechanism,” says Mads Eggert Nielsen, a biologist in the Department of Science Plants and Environments from the University of Copenhagen.

According to Mads Eggert Nielsen and his fellow researchers from the Department of Plant and Environmental Sciences and the University of Paris-Saclay, the essence of this defense mechanism can be reduced to two genes, PEN1 and SYP122. Together they help form a sort of plug in plants that blocks the invasion of fungi and fungus-like organisms.

“We have discovered that if we destroy these two genes in our model plant, Arabidopsis (Arabidopsis), we open the door to the entry of pathogenic fungi. We’ve found that they’re essential for forming that cell wall-like plug that defends against fungi. Interestingly, it appears to be a universal defense mechanism found in all land plants,” says Mads Eggert Nielsen, lead author of the study, published in the journal eLife.

Originating from a 470 million year old plant

The research team tested the same function in liverwort, a direct descendant of one of Earth’s earliest land plants. By taking the two corresponding genes in the liverwort and inserting them into the Arabid, the researchers examined whether they could identify the same effect. The answer was yes.

Model plant Thale Cress

Experiments on the model plant Arabidopsis (Arabidopsis) Credit: Mads Eggert Nielsen

“Even though the two plant families to which Arabidopsis and liverwort belong evolved in divergent directions 450 million years ago, they continue to share genetic functions. We believe that this family of genes emerged for the sole purpose of managing this defense mechanism and was therefore one of the bases for plants to establish themselves on earth,” says Mads Eggert Nielsen.

A symbiosis between plants and fungi

While fungi were an obstacle for plants in their transition from a marine algal stage to becoming land plants, they were also a prerequisite. As soon as plants were able to survive attacks by fungi seeking to eat them on land, the next problem they faced was finding nutrients, says Mads Eggert Nielsen:

“Dissolved nutrients like phosphorus and nitrogen are readily available to plants in aquatic environments. But 500 million years ago, the ground as we know it today did not exist, only rocks. Additionally, rock-bound nutrients are extremely difficult for plants to obtain. But not for mushrooms. On the other hand, mushrooms cannot produce carbohydrates, which is why they consume plants. It was here that a symbiotic relationship between plants and fungi is believed to have arisen, which later became the basis for the explosion of terrestrial plant life during this period.

The defense structures that form in a plant do not kill the plant or the fungus, they simply prevent a fungus from invading.

“Since a fungus can only partially enter a plant, we believe a tipping point occurs where both the plant and the fungus have something to gain. Therefore, it has been beneficial to keep the relationship as is. The theory that plants tamed fungi to colonize the earth is not ours, but we provide fodder that supports this idea,” says Mads Eggert Nielsen.

Can be applied in agriculture

The new findings add an important piece to the puzzle of plant evolutionary history. More importantly, they could be used to make crops more resistant to fungal attack, which is a major problem for farmers.

“If all plants defend themselves in the same way, it must mean that disease-causing microorganisms – such as powdery mildew, stripe rust and potato mold – have found a way to sneak in. “, extinguish or escape the defenses of their respective host plants. We want to know how they do it. We will then try to transfer the defensive components of the resistant plants to the plants that become diseased, and thus achieve resistance”, explains Mads Eggert Nielsen.

Mads Eggert Nielsen is involved in a research project in the Department of Plant and Environmental Sciences led by Hans Thordal-Christensen and supported by the Novo Nordisk Foundation that aims to make crops more resilient by identifying plant defense mechanisms that micro- disease-causing organisms try to shut down.

Additional Facts

Researchers have long speculated that the PEN1 and SYP122 genes served a particular function with respect to the transition of plants from their aquatic stage as algae to terrestrial plants, but there has been no concrete evidence as to whether if they were actually a prerequisite for plants. ‘ defensive abilities.

Previous studies have shown that by knocking out the PEN1 gene, plants lose their ability to defend against powdery mildew fungi. However, upon knocking out the closely related gene, SYP122, nothing happens. The new research results demonstrate that together the two genes are an important key in the plant’s defense mechanism.

Reference: “SYP12 Plant Syntaxins Mediate Evolutionarily Conserved General Immunity Against Filamentous Pathogens” by Hector M Rubiato, Mengqi Liu, Richard J O’Connell and Mads E Nielsen, 4 February 2022, eLife.
DOI: 10.7554/eLife.73487

Rowan University and Community College of Philadelphia Announce Partnership Expanding Access to 4-Year Degrees

A new program-to-program transfer partnership for eligible Community College of Philadelphia graduates is now available through an agreement between Rowan University and Community College of Philadelphia.

To qualify, students must earn an associate’s degree in science, technology, engineering, and mathematics, or other approved majors, and be admitted to Rowan’s corresponding majors.

Rowan’s president, Dr. Ali Houshmand, noted that the partnership extends a history of support for students transitioning from area community colleges to the Glassboro-based university.

Ali Houshman. (File photo)

“Community College of Philadelphia has very high standards, so we know their students will do well at Rowan,” Houshmand said. “We’ve created a variety of pathways for community college graduates to go on and earn an affordable four-year degree.”

Graduates of these specific associate degree programs transfer with advanced standing into a specific bachelor’s degree program at the transferring college. Participating study programs in the partnership with Rowan University include Biology and Biological Sciences, Black Studies, Chemistry, Computer Science, Construction Management, Mathematics and Sound Recording and Music Technology.

“The College is delighted to partner with Rowan University to ensure that our graduates can complete their undergraduate degree in a seamless and affordable way,” said President Dr. Donald “Guy” Generals. “Not only is Rowan a nationally ranked public research institution, it has an excellent reputation for preparing students for the job market. The latter is more important than ever.

Eligible students will receive scholarships to reduce their tuition to state rates. Many graduates are active in the Greater Philadelphia Regional Louis Stokes Alliance for Minority Participation, a national organization that encourages students from underrepresented groups to pursue studies in STEM fields. Launched in 1994, the Greater Philadelphia Regional LSAMP includes Cheyney, Lincoln, and Delaware State Universities, which represent historically black colleges and universities, as well as Community College of Philadelphia, Rowan University, University of Delaware, Drexel University, University of Pennsylvania and Temple University. .

Eligible students will also be able to access Rowan’s LSAMP and STEM programs while attending the College, and be considered for entry into Rowan’s Research Experiences programs for undergraduates.

Clinical Trial Imaging Market Size, Scope and Forecast

New Jersey, United States – This Clinical Trial Imaging Market the research examines the status and future prospects of the Clinical Trial Imaging market from the perspective of competitors, regions, products, and end applications/industry. The global clinical trial imaging market is segmented by products and applications/end industries in this analysis, which also analyzes the various players in global and key regions.

The clinical trial imaging market analysis is included in this report in its entirety. Extensive secondary research, primary interviews, and internal expert reviews have been incorporated into the Clinical Trial Imaging report market estimates. These market estimations have been considered by researching the effects of different social, political, and economic aspects, as well as current market dynamics, on the growth of the Clinical Trial Imaging market.

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Key Players Mentioned in the Clinical Trial Imaging Market Research Report:

Parexel International Corporation, Biomedical Systems Corporation, Biotelemetry Cardiovascular Imaging Technologies LLC, Intrinsic Imaging LLC, Radiant Sage LLC, Worldcare Clinical, LLC.

Porter’s Five Forces Analysis, which explains the five forces: customer bargaining power, distributor bargaining power, threat of substitute products, and degree of competition in the clinical trial imaging market , is included in the report along with the market overview, which includes market dynamics. It describes the various players that make up the market ecosystem, including system integrators, intermediaries, and end users. The competitive environment of the Clinical Trial Imaging market is another major topic of the report. For better decision-making, the research also provides in-depth details of the COVID-19 scenario and its influence on the market.

Clinical Trial Imaging Market Segmentation:

Clinical Trial Imaging Market, By Modality

• Computed tomography
• Magnetic resonance imaging
• Ultrasound
• Positron emission tomography
• Radiography
• Echocardiography
• Other modalities

Clinical Trial Imaging Market, By End User

• Pharmaceutical companies
• Biotechnology companies
• Manufacturers of medical devices
• Contract research organizations
• University and government research institutes
• Other end users

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Scope of Clinical Trial Imaging Market Report

ATTRIBUTES DETAILS
ESTIMATED YEAR 2022
YEAR OF REFERENCE 2021
FORECAST YEAR 2029
HISTORICAL YEAR 2020
UNITY Value (million USD/billion)
SECTORS COVERED Types, applications, end users, and more.
REPORT COVER Revenue Forecast, Business Ranking, Competitive Landscape, Growth Factors and Trends
BY REGION North America, Europe, Asia-Pacific, Latin America, Middle East and Africa
CUSTOMIZATION SCOPE Free report customization (equivalent to up to 4 analyst business days) with purchase. Added or changed country, region and segment scope.

Answers to key questions in the report:

1. Who are the top five players in the Clinical Trial Imaging market?

2. How will the clinical trial imaging market evolve in the next five years?

3. Which products and applications will capture the lion’s share of the clinical trial imaging market?

4. What are the drivers and restraints of Clinical Trial Imaging Market?

5. Which regional market will show the strongest growth?

6. What will be the CAGR and size of the Clinical Trial Imaging market throughout the forecast period?

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Verified Market Research® is a leading global research and advisory firm that for over 10 years has provided advanced analytical research solutions, personalized advice and in-depth data analysis to individuals and businesses seeking accurate research, reliable and up to date. data and technical advice. We provide insight into strategic and growth analytics, the data needed to achieve business goals, and help make critical revenue decisions.

Our research studies help our clients make superior data-driven decisions, understand market forecasts, capitalize on future opportunities, and maximize efficiency by working as a partner to deliver accurate and valuable insights. The industries we cover span a wide spectrum, including technology, chemicals, manufacturing, energy, food and beverage, automotive, robotics, packaging, construction, mining and the gas. Etc.

At Verified Market Research, we help in understanding holistic market indicator factors and most current and future market trends. Our analysts, with their deep expertise in data collection and governance, use industry techniques to gather and review data at all stages. They are trained to combine modern data collection techniques, superior research methodology, subject matter expertise and years of collective experience to produce informative and accurate research.

Having served over 5000 clients, we have provided reliable market research services to over 100 Global Fortune 500 companies such as Amazon, Dell, IBM, Shell, Exxon Mobil, General Electric, Siemens, Microsoft, Sony and Hitachi. We have co-consulted with some of the world’s leading consulting firms such as McKinsey & Company, Boston Consulting Group, Bain and Company for custom research and consulting projects for companies around the world.

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Computational Biology Market Size and Forecast to 2029 – Chemical Computing, Accelrys, Certara, Compugen, Entelos, Insilico Biotechnology, Genedata, Leadscope, Simulation Plus, Schrodinger, Rhenovia Pharma, Nimbus Discovery – Instant Interview

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The Computational Biology Market The 2022-2029 report provides a detailed analysis of market dynamics with a focus on secondary research. The report sheds light on the current status of the market size, share, demand, development patterns and forecast for the coming years.

The research report aims to provide reliable and useful information and data on the Computational Biology industry in the domestic and international markets, thus helping market leaders, investors, small businesses and others to gain insights into the market all over the world. The report provides players in the global Computational Biology market with the necessary information to make key decisions regarding international markets such as expansion and investments. The Computational Biology report anticipates future economic, business and political factors and trends that may impact their performance at the regional and international levels. Multinational companies that are leading in the Computational Biology market in recent years and topics related to selected markets are covered in the report.

The global computational biology market size is expected to reach a CAGR of 39% during the period 2022-2029.

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Key market players profiled in the report include:

Computational Chemistry, Accelrys, Certara, Compugen, Entelos, Insilico Biotechnology, Genedata, Leadscope, Simulation Plus, Schrodinger, Rhenovia Pharma, Nimbus Discovery

The market report analyzes the major players dominating the Computational Biology market. The study reviews the characteristics of the Computational Biology industry and the major manufacturers in the global market. The report provides an enhanced and comparative understanding of the market using financial and SWOT analysis. Additionally, the current technology integrations done by the manufacturers for the operational efficiency and to improve the market value, the current financial situation of the manufacturers is explored in the report. The study also analyzes the positive and negative impact of the covid-19 pandemic on manufacturers and the survival strategies adopted by gamers.

Computational Biology Market Segment By Type:

.

Computational Biology Market Segment By Application:

Cellular and Biological Simulation, Pharmacogenomics, Drug Discovery, Drug Development, Lead Optimization, Lead Discovery, Pharmacokinetics, Disease Modeling, Clinical Trials

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REGIONAL ANALYSIS

  • North America (United States, Canada, Mexico)
  • Europe (Germany, France, UK, Russia, Italy)
  • Asia-Pacific (China, Japan, South Korea, India, Southeast Asia)
  • South America (Brazil, Argentina, Colombia, etc.)
  • Middle East and Africa (Saudi Peninsula, United Arab Emirates), Egypt, Nigeria and South Korea)

Key Questions Answered by the Report

(1) How will the global computational biology market perform during the forecast period? How big will the market be in terms of value and volume?

(2) Which segment will drive the global computational biology market? Which regional market will show strong growth in the future? What are the reasons?

(3) How will Computational Biology market dynamics change due to the impact of future market opportunities, restraints, and drivers?

(4) What are the key strategies adopted by players to sustain themselves in the global Computational Biology market?

(5) How will these strategies influence the growth and competition of the Computational Biology market?

Key information that the study will provide:

  • The 360 ​​degree overview of the Computational Biology Market is based on a global and regional level
  • Market Share and Revenue by Key Players and Emerging Regional Players
  • Competitors – In this section, various major Computational Biology industry players are studied with respect to their company profile, product portfolio, capacity, price, cost and revenue.
  • A separate chapter on Computational Biology Market Entropy to better understand Leader’s aggressiveness towards the market [Merger & Acquisition / Recent Investment and Key Developments]
  • Patent analysis Number of patents/trademarks filed in recent years.

Contents:

Chapter 1: Introduction, Market Driving Product Study Objective and Research Scope Computational Biology Market

Chapter 2: Exclusive Summary – the basic information of the Computational Biology Market.

Chapter 3: Viewing Market Dynamics – Computational Biology Drivers, Trends and Challenges

Chapter 4: Introducing Porters Five Forces Computational Biology Market Driver Analysis, Supply/Value Chain, PESTEL Analysis, Market Entropy, Patent/Trademark Analysis.

Chapter 5: View 2015-2020 by type, end user and region

Chapter 6: To evaluate the top manufacturers in the Computational Biology Market including their Competitive Landscape, Peer Group Analysis, BCG Matrix and Company Profile.

Chapter 7: To assess the market by segments, by countries and by manufacturers with revenue share and sales by key countries in these various regions.

Chapter 8 & 9: Display of appendix, methodology and data source

Conclusion: At the end of the Computational Biology Market report, all findings and estimates are given. It also includes key drivers and opportunities along with regional analysis. Segment analysis is also provided in terms of type and application.

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BitLife: how to become a marine biologist

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Most recent BitLife challenge, the Under the Sea Challenge, has arrived! Based on the story of The little Mermaid, the challenge asks you to become a marine biologist who marries royalty! This guide will teach you how to become a marine biologist in BitLife.

How to Become a Marine Biologist in BitLife

When you start a new character, age until you graduate from high school. Maintain high intelligence so you can successfully enroll in college, and as a bonus, get a scholarship that pays your tuition. While it’s not a problem if you’re starting in a country where post-secondary education is free, student debt becomes a major problem in others. When you enter university, choose biology as your major. If it doesn’t appear right away, age or restart your game until it appears. Enroll in the program and complete the degree to proceed to stage two.

Related:
BitLife: How to Start Rumors About Friends

After graduating from college in biology, return to the Profession tab and go to graduate school. You must have a graduate degree to become a marine biologist. Enter graduate school and age until you are done. After completing your higher education, return to the Profession tab and select full-time job vacancies. Check out the listings for a marine biologist position. If he doesn’t appear, get older and recheck the lists every year until he does. Apply for the interview and succeed to become a marine biologist. Alternatively, you can apply and become a Junior Marine Biologist instead. If you do, work hard every year until you’re promoted to marine biologist.

Once you become a Marine Biologist, you will successfully complete one of the Under the Sea Challenge tasks in BitLife. For more information on a previous BitLife challenge, visit our coverage here.

BitLife is available on Android and iOS.

Pumpkin Toads’ Inner Ears Make Them Bad at Jumping

2016’s Halloween brought us a new holiday character that was more confusing than terrifying. We’re talking about David S. Pumpkins, and we still have so many questions. Along with his skeleton sidekicks, he made dressing up as a pumpkin with a curly wig and double-holstered guns one of the best Halloween costumes that year.

The Pumpkin Toad, however, has been dressing as a pumpkin since long before recorded history. These neon orange frogs are the world’s smallest and cutest jack-o’-lantern. They are also possibly the worst jumpers in the world. When frightened – whether of an undead bride or a natural predator – Pumpkin Toads leap into the air before making a totally uncontrolled crash landing.

Jumping is sort of a key characteristic of frogs, so it’s unusual for them to be so terrible. That’s why Richard Essner Jr. of the Department of Biological Sciences at Southern Illinois University, and his colleagues, took an interest in them and sought to understand why they are such awful acrobats. Their findings were published in the journal Scientists progress.

“I’ve been working on jumps for a long time and finally started thinking about landing behavior. I was interested in trying to find something, a group that might have ancestral behavior and morphology that would allow me to get a better idea of ​​what the jump looked like when it first appeared,” said Essner Jr. told SYFY WIRE.

The search led him to a group of tailed frogs in the Pacific Northwest of the United States and their closest relatives in New Zealand. They separated from the rest of the frogs about 200 million years ago and could jump but could not control landing. Scientists have pinned tailed frog behavior on an evolutionary holdover from a time after powered jumping evolved, but before frogs figured out how to stick landing. Next, Essner Jr. took a look at the Pumpkin Toad, a miniature frog from Brazil.

“It was really similar to what I had seen in tailed frogs and New Zealand frogs, and it didn’t make much sense. These little frogs are part of the larger group of frogs that jump really well. So we were trying to figure out why their landing behaviors are so similar,” said Essner Jr.

When Pumpkin Toads jump in the air, they often flip or turn around (you can see them in action here). They land on their backs about a third of the time, and usually with their legs fully extended. In comparison, most frogs jump with precision and land with their legs tucked under them so they can jump again if they need to. The researchers had the idea that it might have something to do with their small size and how they impede a structure in the ear known as the semicircular canal.

“Being able to detect angular acceleration requires the movement of a fluid contained in the semicircular canals. The smaller this conduit, the greater the proportional resistance you get. Relatively speaking, there is more fluid coming into contact with the walls of the conduit, which impedes its flow,” Essner Jr. said.

Basically, as soon as they break contact with the ground, pumpkin toads lose all sense of their orientation in space and begin to spin until gravity pulls them back down. Therefore, they do not jump very often. During laboratory observations, scientists found that they only really jump when they felt threatened and wanted to quickly but clumsily escape. Fortunately, their small size – some of them barely larger than a housefly – is also an advantage, at least when it comes to crash landings.

“When you’re very young, you don’t really have problems with bone fractures, but they may damage soft tissue or perforate. One of the interesting things about this group is that “They have extra bones. They have bony plates in their backs and extra bones in their skulls. This can help protect them from injury or predation,” Essner Jr. said.

Their coloring also helps. This is a warning to predators that they are poisonous and best left alone. When you’re very small and very clumsy, you take all the help you can get. This is certainly the case for pumpkin toads, in the world of frogs they do their own thing.

Keene State professor collaborates on app to help people with autism

Keene State professor Lawrence Welkowitz featured with SpeechMatch in 2014. “It’s been a 10-year odyssey,” Welkowitz said of the app. File photo Sentinel/Michael Moore

Story produced by Keene Sentinela member of

KEENE, NH – A Keene State professor has been granted a US patent for an app created to improve communication for people with autism.

The patent was presented in April to Lawrence Welkowitz, chair of the college’s psychology department.

SpeechMatch, which Welkowitz created with British musician Robert Taub, provides immediate visual feedback for matching important speech patterns, including volume, pitch and rhythm.

The app became available for download on Apple and Google Play devices two years ago, and has taken years to develop.

The idea grew out of Welkowitz’s long-term observations of autistic people’s conversational speech patterns and how they may differ from other people off the spectrum.

“People on the spectrum are mistakenly thought to be unempathetic and uninterested in what other people are saying, but the truth is that their brains don’t tune into certain speech patterns,” said said Welkowitz, who has studied autism spectrum disorders since the late 1990s.

Autism spectrum disorders (ASD) are neurological and developmental disorders that affect “the way people interact with others, communicate, learn and behave,” according to the National Institute of Mental Health. According to a 2017 study from the Centers for Disease Control and Prevention, more than five million American adults are estimated to have autism spectrum disorder. The CDC Autism and Developmental Disabilities Surveillance Network estimates that 1 in 44 American children has an ASD, based on 2018 data.

The SpeechMatch app provides immediate visual feedback to match important speech patterns, including volume, pitch and rhythm.

Feedback provided by SpeechMatch can allow app users to communicate more effectively and “shape the way they shape their speech in a way that is more acceptable to most people,” Welkowitz said.

For example, someone on the spectrum can use it to decipher and match appropriate speech volumes, he explained.

The app includes a built-in library of more than 100 phrases that vary in emotional content, like happy, sad, sarcastic, funny, and “pleasant and unpleasant surprise,” Welkowitz said. App users can also save and use their own custom phrases.

An app user will hear the selected phrase and see its generated sound wave. Once they say the phrase, a sound wave will provide an immediate percentage match of patterns such as volume and pitch.

Taub is no stranger to audio processing software. He helped start a company that developed the algorithms later sold for use in the popular video game Guitar Hero, according to Welkowitz.

“Human communication is critically important to all of us…It’s very exciting to be involved in building a platform that helps people communicate more fully,” said Taub, director of music at the Arts Institute of the University of Plymouth in England, in a Keene State press release about the patent.

Welkowitz said it was Taub’s experience developing music matching algorithms that led him to contact him to create SpeechMatch.

The app was the basis of research funded by NH-INBRE (Innovative Biomedical Research Excellence) through Dartmouth-Hitchcock Medical Center and the National Institute of Health (NIH) that evaluated SpeechMatch’s ability to help people with autism improve their conversational speech, according to the release. NH-INBRE distributes NIH funds to colleges statewide to fund research projects.

SpeechMatch has been successful, showing “that people with autism can improve in terms of speech adaptation,” Welkowitz said, based on clinical trials and testimonials from those who have experience with speech. application, either themselves or through a loved one.

Eric Hollander, director of the Autism and Obsessive-Compulsive Spectrum program at Albert Einstein College of Medicine in New York, said his patients have found SpeechMatch helpful, according to a testimonial on the app’s website.

“After years of development and study, I am impressed that SpeechMatch has come out of the research lab and is now available for public use as a viable clinical tool,” Hollander’s quote reads.

Although the main function of the app is to improve communication for people with autism, it can also serve other purposes. For example, someone recovering from a stroke can use SpeechMatch to help regain speech, Welkowitz said.

“It’s been a 10-year odyssey,” he said of the app. “It’s been my heart and soul for over 10 years.”

SpeechMatch is available for free download from the Apple and Google Play app stores. More information can be found at www.speechmatch.com.

You can reach Caitlin Howard at 352-1234 ext. 1441 or choward@keenesentinel.com.


These articles are shared by partners of The Granite State News Collaborative. For more information, visit collaborativenh.org.

Honoring the LGBTQ+ community in science

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June 24, 2022

June is LGTBQ+ Pride Month — a time to celebrate the contributions the LGTBQ+ community has made to society and throughout history.

At Arizona State University, a faculty member supports LGTBQ+ students in STEM and shares what she is doing to help these students succeed in science.

Katelyn Cooper and members of her lab. Photo courtesy of Katelyn Cooper
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Katelyn Cooper is an assistant professor in the School of Life Sciences, an expert in undergraduate biology educationand was recently named one of NBC’s Pride 30: The Next Generation. She also developed a course-based research experience for ASU Online students to create publishable research. She is passionate about inclusivity and studies LGBTQ+ student experiences in academia.

Here, Cooper talks about her own experience within the LGBTQ+ community and how she makes her students feel welcomed and valued.

Question: What does Pride month mean to you?

Answer: Pride Month reminds us of the importance of standing up for our rights and privileges as LGBTQ+ individuals. It is also a time to feel exceptionally proud of this identity and the progress that we, and especially the people who came before us, have made. I also think it’s time to reflect on how far we’ve come and what progress we have to make in the years to come.

Q: Can you tell us how and why you are working to create more inclusive learning environments for students?

A: It is important to consider that our students come into our classrooms with different backgrounds that will influence their experiences in science lessons. Therefore, we want to be intentional to maximize the experiences of all students in our courses and not just those in the majority groups. Striving to create more inclusive learning environments means first considering that our classes include women, gender non-binary people, students of color, students with disabilities, LGBTQ+ students, and students with struggling with mental health issues. Additionally, some students are financially unstable, some commute over an hour to get to ASU, and some are the first in their families to attend college. Each of these identities and characteristics can affect how that student experiences a science lesson.

I start trying to create inclusive science learning environments by surveying my students to see who is in my classes and what challenges they can expect to encounter. Then, I can draw on my own research and the research of others who study how to create inclusive scientific learning environments, to make decisions to maximize inclusion. For example, we know that women value group chats more when they have a friend in their group, and we know that LGBTQ+ students feel safer when they can choose their groups. Therefore, if I want to maximize comfort and performance for female and LGBTQ+ students, I may intentionally let students choose who they want to work with throughout the semester.

Q: Tell us about the courses you teach and the importance of LGBTQ+ representation in your area of ​​research.

A: I teach course-based undergraduate research experiences, or CURE, where students engage in a real research project in biology education with the intention of publishing their data. We know that LGBTQ+ students leave science at higher rates than their straight and cis peers, but we also know that more diverse science collaborations lead to better, more objective science. Therefore, it is important to increase the percentage of LGBTQ+ people doing science. Every CURE I have taught has resulted in at least one peer-reviewed scientific publication co-authored by students. Of CURE’s 63 students, the LGBTQ+ community is well represented, and through this diversity, we can be more confident that the various inherent biases we unwittingly bring to our research are counteracted.

Q: How did you first feel in a science class or lab?

A: In middle school, I fell in love with science during my first chemistry class. With each additional chemistry lesson, I became more excited about science. But, as an LGBTQ+ person, I had no role models to look up to. I didn’t know many LGBTQ+ people, let alone LGBTQ+ scientists. So even though I felt like I had found what I wanted to study, I was still looking for an example that LGBTQ+ people could do well in academic science. You can feel very lonely when you don’t see yourself reflected by a domain you want to join.

Q: How can different people from different backgrounds bring better study in science?

A: People from different backgrounds will bring different perspectives to the table, which allows teams of scientists to think about issues more holistically and also helps counter biases present in our thinking.

Q: Who mentored or inspired you to come and explore this group of students?

A: My former thesis supervisor and now colleague, Sara Brownell, was the first openly LGBTQ+ mentor I knew in science. I was very lucky that the person studying exactly what I wanted to study in graduate school was also a proud member of the LGBTQ+ community. Sara helped me realize the importance of not check your identities at the gate as a scientist.

Sara and I began to systematically study the experiences of LGBTQ+ people in academic biology. Throughout this process, I became more and more comfortable with my own identity, especially as I learned how similar my experiences were to those of other students.

Over the years we have developed this line of research, and now it is one of the main areas of interest of ASU Research for Inclusive STEM Education Center; more recently, we received a grant from the NSF to study the impact of LGBTQ+ instructors speaking to their students in less than three seconds in the classroom. We find that this can have a very positive impact, and disproportionately for women and LGBTQ+ students.

Q: Do you have any advice for LGTBQ+ women who want to enter the science field?

A: For women: Research shows that scientists are more likely to hire men, pay them more, and mentor them more, showing how important it is for women to find mentors who will support them, defend and promote their achievements. If you’re a woman wanting to get into science, I often recommend finding a mentor as soon as possible. For example, it could be someone in your local community who has a career in science, a teaching assistant, an instructor, or a professor. When you encounter new and challenging experiences, it helps to know that others have faced similar challenges and succeeded. Mentors can give you advice on how to navigate uncertain situations, help you identify opportunities to seize and opportunities to say no to, support you when you’re struggling, and praise you when things are going well.

For LGBTQ+ students: I think the science field as a whole is making great strides towards LGBTQ+ inclusion. So my biggest advice would be to start connecting with people who will help you navigate the field. There are now fantastic resources like 500 Queer Scientists, a website showcasing over 1,500 LGBTQ+ people in the science community. Our scientific organizations and societies have also become increasingly concerned with making their respective communities more inclusive. For example, the American Society of Cell Biology formed the ASCB LGBTQ+ Committee to assess, promote, and ensure the inclusion of LGBTQ+ members, with the explicit purpose of providing career guidance to LGBTQ+ people. There are many other scientific societies that have formed similar committees. So I suggest leveraging the resources that have been created to find a network that does some truly amazing science and by whom you feel accepted.

Story by Stephanie Rodriguez, Senior Media Relations Coordinator, EdPlus at Arizona State University.

ASU Announces Spring 2022 Graduates

Arkansas State University at Jonesboro announced the slate of spring 2022 graduating students beginning May 7.

Undergraduate students with a cumulative grade point average of 4.0 are designated as Summa Cum Laude. Those with a GPA of 3.8 to 3.99 graduated Magna Cum Laude, and those with a GPA of 3.6 to 3.79 graduated Cum Laude, according to a press release.

Southeast Arkansas graduates include:

Almyra: Wyatt R. Luebke, Master of Science in Agriculture, General Agriculture;

DeWitt: Alesha Dare DeBerry Jones, Master of Science in Education, School Guidance;

DeWitt: David Brown, Education Specialist, Education Leadership;

DeWitt: Karli Ann Rieves, Associate in Applied Science, Physiotherapist Assistant;

DeWitt: Ashtyn Brooke Beck, BSc, Psychology, Magna Cum Laude;

DeWitt: Kayla Beth Poor, BSN, Nursing;

Saint Charles: Caitlin M. Jones, Science Associate, AS En Route;

Stuttgart: Megan Boyd McCarley, Master of Science in Education, School Guidance;

Stuttgart: Corinne M. Keller, Master of Science in Mass Communications, Radio Television;

Stuttgart: Sabrina Jean Simpson, Master of Social Work, Social Work;

Stuttgart: Logan M. Erstine, Bachelor of Science, Finance;

Stuttgart: Meredith Maier, Bachelor of Science, Business Administration;

Stuttgart: Lane P. Eldridge, BSc in Agricultural, Plant and Soil Sciences;

Stuttgart: Cameron James Seidenschwarz, BSc in Agriculture, Plant and Soil Sciences;

Stuttgart: Corinne M. Keller, Certificate of Competence, Sports Production;

Tichnor: Makayla Whiting, Bachelor of Science, Communication Disorders, Magna Cum Laude;

Tichnor: Shelby Elizabeth Long, Bachelor of Science in Agriculture, Farm Business;

Tichnor: Colby S. Turner, BS in Agriculture, Plant and Soil Sciences;

Warren: Kerri Lynn Bennett, Master of Arts, Heritage Studies;

Lake Village: Sara Ellen Johnson, Bachelor of Science in Education, Elementary Education;

Lake Village: Lily Sadler, Bachelor of Education, Social Sciences;

Rison: Krista Cotton, Education Specialist, Education Leadership;

Fordyce: Carrie Marie Shankles, Master of Science in Education, School Guidance;

Arkansas City: Kayla Bryant Robertson, Master of Science in Education, Educational Leadership;

Dumas: Landy Michelle Zuniga, Bachelor of Science, Biological Sciences;

McGehee: Dorissa Moreau Kaufman, Education Specialist, Education Leadership;

McGehee: Drew A. Wilson, Scientific Associate, AS En Route;

McGehee: Mary Rebekah Dunn, Bachelor of Science in Nursing, Nursing, Magna Cum Laude/Honours Program;

Tillar: Jadacee Latierra Glover, Science Associate, AS En Route;

Monticello: Olivia Adden Pesaresi, Doctor of Physical Therapy, Physiotherapy;

Monticello: Paul Ryan Smith, Doctor of Physical Therapy, Physiotherapy;

Monticello: Emily Madison Johnston, Master of Science in Education, School Guidance;

Monticello: Haley Nichole Hill, Bachelor of Science in Education, Special Education, Magna Cum Laude;

Hensley: Hayley Anne Capps, Bachelor of Science in Education, Primary Education, Cum Laude;

Prattsville: Ashton L. Archer, BScN, Nursing, Magna Cum Laude/Honours Program;

Redfield: Abigail R. Cline, Scientific Associate, AS En Route;

Sheridan: Anna Marie Handleloser, BSc, Strategic Communications, Magna Cum Laude/Honours program;

Sheridan: James A. Loyd, BSc, Health Studies;

Sheridan: Logan Bryce Mitchell, BSc, Global Supply Chain Management, Magna Cum Laude/Honours Program;

Sheridan: Heath Daniel Alexander, Bachelor of Science in Nursing, Nursing, Cum Laude/Honours Program;

Sheridan: Anna Marie Handleloser, Certificate of Proficiency, Public Relations and Advertising, Magna Cum Laude/Honors Program;

Pine Bluff: Nicholas D. Woodfork, Master of Arts in Teaching, Teaching;

Pine Bluff: Zoe’ D. Brown, Master of Science, Strategic Communications;

Pine Bluff: Brittani Shennille Hill, Master of Science, Early Childhood Services;

Pine Bluff: Korinne La’Tori Thomas, Bachelor of Arts, Psychology;

Pine Bluff: Joel Clayton Rogers, Bachelor of Science, Engineering Technology, Cum Laude/Honors Program;

Pine Bluff: LaPorsche’ D. Roshell-Scott, Bachelor of Science, Business Administration;

Redfield: Hanna Claire Stone, BSc, Communication Disorders, Magna Cum Laude;

Sherrill: Amber Marissa Adkins, Masters of Accounting, Accounting;

White Hall: Ross Edward Ellis, Bachelor of General Studies, General Studies;

White Hall: Devin Blair Kidwell, Bachelor of Science, Finance;

White Hall: Ryan Matthew Turbeville, Bachelor of Science, Creative Multimedia Production;

White Hall: John Berry Horton III, Bachelor of Science in Agriculture, Farm Business;

White Hall: Matthew T. Adams, Bachelor of Science in Nursing, Nursing;

Grady: Carnecia Lakaya Mays, Bachelor of Social Work, Social Work;

Star City: Tyler Mackenzie Courson, Master of Science in Agriculture, General Agriculture;

Star City: Edward D. Potts II, Master of Science in Education, Educational Leadership;

Star City: Emily R. Snyder, Education Specialist, Education Leadership;

Star City: Ryan S. Davis, Scientific Associate, AS En Route;

Star City: Karley N. Spivey, Scientific Associate, AS En Route;

Star City: Jaycee Dawn Merritt, Bachelor of Science, Communication Disorders, Cum Laude.

Jill Biden urges unity on cancer at Trump, DeSantis Home of Florida

  • On Thursday, First Lady Jill Biden urged unity over cancer screenings and treatments in Palm Beach.
  • “We have to fight against this disease, not against each other,” she said.
  • The first lady will travel to Surfside on Friday to mark the one-year anniversary of the condo collapse.

WEST PALM BEACH, Fla. – First lady Jill Biden called for unity Thursday just 4 miles from former President Donald Trump’s perennial home in Mar-a-Lago and Republican Gov. Ron DeSantis’ lot – the one of her husband’s most vocal critics.

The first lady was promoting the Biden administration’s cancer initiative, which she called a “key pillar” of what President Joe Biden calls his “Unit Agenda.”

“Cancer has the power to change us, but it also connects us,” Jill Biden told an audience gathered in the ballroom of the Hilton West Palm Beach. “It forces us to look for answers to get help, to heal. It tears apart the things that divide us, reminding us that we have to fight this disease, not against each other.”

The remarks came as the Biden administration and Ron DeSantis continue to clash over numerous issues, including COVID-19 vaccination policies. Trump moved from his private club Mar-a-Lago in Bedminster, New Jersey, for the summer, but continues to make fun of Joe Biden in speeches.

But on Thursday, the first lady focused on an issue meant to cross partisan lines, as she broadly appealed for public support for cancer screening and treatment.

“The disease doesn’t care who you voted for,” Jill Biden said. “It’s not a red or blue problem. It’s an American problem. It’s a global problem. It will take all of us to end cancer as we know it.”

Earlier in the day, Jill Biden visited FoundCare Palm Springs, a nearby federally-licensed health center.

The trip aimed to highlight private sector collaborations. FoundCare receives help from the Promise Fund of Florida, which pays for cancer screenings and treatment for women who are uninsured or do not have adequate coverage to pay for their health care.

The organization also connects patients with ‘navigators’ – staff who help patients with transportation, translation, childcare and other logistical services. Jill Biden on Thursday praised the organization for finding gaps in health care and addressing patient needs.

Joe Biden announced in February that he was reviving the Cancer Moonshot started under his former boss, then-President Barack Obama. The goals of the initiative are to reduce the cancer death rate by at least half over the next 25 years and improve the lives of people with cancer and their families.

The disease is personal to the Bidens, who lost their son Beau to brain cancer in 2015. On Thursday, Jill Biden called their cancer work a “mission of our lives” for herself and the president.

Last year, Congress partially funded Joe Biden’s request for a new agency called the Advanced Research Projects Agency for Health, or ARPA-H, with the intention of authorizing more. The Biden Administration pitched the agency as a way to fund ambitious and risky biomedical research that would aim to develop transformative new technologies, whether to cure cancer or Alzheimer’s disease.

“There’s nothing political about it,” Nancy Brinker, Republican and co-founder of The Promise Fund, told Insider in an interview. “I’ve always respected Dr. Biden. She’s wonderful, she’s as sincere as she can be and she gets things done and they both have caring hearts.”

Brinker served as United States Ambassador to Hungary from 2001 to 2003 and United States Chief of Protocol from 2007 until the end of the George W. Bush administration. Brinker also founded Susan G. Komen for the Cure, a nonprofit breast cancer research and advocacy organization.

The Promise Fund is set to receive a $1 million federal grant from Congress, and also received a grant from the state of Florida, which increased cancer research funding this year to $100 million.

Florida’s record funding increase was spurred in part by Florida First Lady Casey DeSantis, who underwent chemotherapy for breast cancer and was declared “cancer-free” in March. In another sign that the issue has bipartisan resonance, Casey DeSantis spoke about the importance of screenings and the Florida governor’s office hinted that a cancer messaging campaign is coming.

Jill Biden’s comments on Thursday were delivered as part of a two-day visit to Florida. On Friday, Jill Biden will attend a remembrance ceremony in Surfside, Florida, to mark the first anniversary since Champlain Towers South collapse which killed 98 people.

A year ago, Ron DeSantis and Joe Biden showed bipartisan unity after the tragedy, with the governor calling out the president “Very encouragingThe governor’s office has yet to release the DeSantises’ schedule for Friday.

Chemist-turned-techie Mark Day retires from NERSC

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June 23, 2022 – When Mark Day arrived at the National Energy Research Scientific Computing Center (NERSC) at Lawrence Berkeley National Laboratory (Berkeley Lab) five years ago, “I found my tribe,” he said. This month, the self-proclaimed “recovering scientist” is retiring from a more than 30-year career with the University of California (UC) system, including his years at NERSC.

Mark Day, pictured in Porto, Portugal, is looking forward to traveling more during his retirement. Credit: Mark Day.

Day’s career at UC began in 1982 as a Ph.D. pharmaceutical chemistry student. As part of his research, Day applied nuclear magnetic resonance spectroscopy to resolve peptide structures. This led to subsequent work in the Department of Radiology at UC San Francisco (UCSF) where he applied magnetic resonance imaging (MRI) in novel ways, coaxing data from digital images created to clinical use. “I loved science, but I really fell in love with computer science,” Day said. “Also, I was really good at creating the tools needed for computer analysis, so I got into this job.”

During his years at UCSF, Day moved into administration, a role in which he “found little joy.” So when he accepted a position with NERSC’s Infrastructure Services Group (ISG), he felt he would come home. “In fact, many of us are recovering scientists at NERSC,” Day said. “I guess it’s kind of the same attraction for all of us: we always love being involved in science and the challenge of helping others do their jobs using the computing tools at our disposal.”

It was also important for Day to be involved in a mission-driven organization like NERSC: “Even though I wasn’t directly the one saving lives at UCSF, I knew I was part of a who did,” Day said. “It’s the same at NERSC: even though I’m not directly advancing scientific knowledge, I’m part of an organization that helps make that happen, and that’s always been important to me.”

Mark Day and his wife Amy are cycling in the Alentejo region of Portugal. Credit: Mark Day.

During his tenure at NERSC, Day is proud to have been part of the team that implemented Spin, a “container” system that allows scientists to easily stand together and share technology tools, such as websites, databases and data analysis tools. “I think NERSC is kind of famous for taking the friction out of science, and Spin is a great example of that.”

He also cited the recently deployed Federated Identity Project, which allows scientists to access NERSC systems and resources through their home institution logins. “I always felt like we were part of a pretty strong team at NERSC, so all the things I’d like to cite are really team accomplishments,” he said.

“We are extremely fortunate to work with colleagues of Mark’s caliber,” said ISG Group Manager Cory Snavely, who hired Day in 2017. “He’s not only a brilliant technologist, but he’s also articulate, generous and has a fantastic sense of humor. Mark has been central to all of the band’s projects, and especially with our Federated Identity initiative, but he also made the job fun,” Snavely said.

Day said he will miss the people he works with and the intellectual challenges of supporting science. “Whether it was figuring out how to apply a new technology or attending a seminar to learn some of the science behind detecting dark matter, I was constantly challenged at NERSC. I think it’s going to be hard to replicate in retirement.

Still, he looks forward to “doing all those things you think you’re going to do but never seem to have time for”, including traveling with his wife Amy, biking, hiking and finishing household projects. long neglected.

About NERSC and the Berkeley Laboratory

The National Energy Research Scientific Computing Center (NERSC) is a user facility of the United States Department of Energy’s Office of Science that serves as the primary high-performance computing center for Office of Science-sponsored scientific research. Located at Lawrence Berkeley National Laboratory, the NERSC Center serves more than 7,000 national laboratory and university scientists who study a wide range of problems in combustion, climate modeling, fusion energy, materials science, physics , chemistry, computational biology and other disciplines. Berkeley Laboratory is a DOE National Laboratory located in Berkeley, California. It conducts unclassified scientific research and is managed by the University of California for the US Department of Energy. Learn more about IT at the Berkeley laboratory.


Source: Margie Wylie, NERSC

Summer nights are no longer “a sound chaos”. Where have all the bugs gone?

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As summer rolls around, I often think of my childhood in Maryland in the 1970s, and invariably, I think of fireflies. Most of the outdoor spaces in my neighborhood were tame spaces – mowed lawns and manicured gardens. Some, however, were left wild, and in the summer these wild spaces were teeming with vegetation.

Dark green vines of honeysuckle, shiny leaves of poison ivy, bright orange threads of the plant parasite known as dodder would drape over bushes and climb trees. And all that growth was an insect paradise. As evening fell and I looked across our back lawn towards the brush I could see a few flashes of fireflies and then as the sun crept away I saw so many more, twinkling and streaming against the darkening backdrop.

The fireflies were by no means alone. The flickering of their lights was accompanied by the chirping of crickets and the cries of locusts, a cacophony of insect sounds that mingled through the air in a unified hum. The noise betrayed to our ears the sheer number of insects that were there and in what amazing variety. The show these insects gave was the most punk rock performance I have ever seen. It started before sunset, lasted until dawn, obeyed no limits and followed no rules. The same heat and humidity that slowed the pace of our lives accelerated the insects. They pupated and emerged, some after years underground, in raucous celebration, voracious consumption and a race to breed.

The show these insects gave was the most punk rock performance I have ever seen.

Are summers full of sights and sounds of insects a thing of the past? Environmental experts have been measuring wild insect populations for decades. In recent years, the news has been dire. Writing in Current Biology in 2019, insect ecologist David Goulson cites studies from Germany and Puerto Rico that report staggering declines over the past quarter-century in total insect biomass and species diversity. In one such study, the total insect biomass collected from the wild by researchers in 2014 was less than a quarter of what it had been using the same methods at the same location in 1989.

Goulson points to several economic reasons why we should pay attention to insect decline. He notes, for example, that three-quarters of the types of crops we grow require insect pollination, “a service estimated at $235-577 billion per year worldwide.” It further appeals to our sense of natural wonder, asking: don’t all species have as much right to be here on the planet as we do?

Why does this happen? The proposed causes of insect decline are too easy to imagine. In a research paper published in the journal Nature in April this year, Outhwaite and his colleagues reported that insect decline is at its worst in places on the planet where large-scale agriculture and the impacts of climate change coincide. A glimpse of hope comes from the observation by Outhwaite and his colleagues that the presence of natural spaces near sites of low-intensity agricultural use – spaces similar to the wild patches that adjoin mowed lawns in my former neighborhood in Maryland, but on a much larger scale – mitigates declines compared to nearby sites without coverage.

Just before the monsoon season, these fireflies congregate in parts of India. This particular image is a stack of 32 images of this tree. (Prathamesh Ghadekar via AP)

The decline in insect populations is alarming. The problem is one symptom among many that we are not treating our planet as we should. As a nature-loving child who grew up to be a biologist studying an insect (the fruit fly Drosophila melanogaster), I find it a symptom of environmental distress that particularly resonates with me.

I believe that radical societal change on a global scale is needed to save us – along with fireflies, crickets, locusts and so many other invertebrate beasts – from environmental destruction and climate change. Yet I wonder when our society will bend to meet the need. And perhaps more importantly, I wonder when, as an individual, will I be ready to step in and do more, change more than my household recycling habits?

How quiet must summer nights get? How devoid of magical flashes of light? The chaos of sound? The noisy life of the little ones?

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Florida biologists capture 18-foot, 215-pound Burmese python

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NAPLES — A team of biologists recently transported the heaviest Burmese python ever caught in Florida, officials said.

The female python weighed 215 pounds, was nearly 18 feet long and had 122 developing eggs, the Conservancy of Southwest Florida said in a news release.

The team used radio transmitters transplanted into male “scout” snakes to study the pythons’ movements, breeding behaviors and habitat use, said Ian Bartoszek, wildlife biologist and project leader in environmental sciences for the conservation program.

“How do you find the needle in the haystack? You can use a magnet, and similarly our male scout snakes are attracted to the biggest females in the world,” Bartoszek said.

This December 2021 photo provided by the Conservancy of Southwest Florida shows biologists Ian Bartoszek, right, and Ian Easterling, center, with intern Kyle Findley and a 17.7-foot, 215-pound female Burmese python captured while following a Male scout snake at Picayune Strand State Forest. [ JC FINDLEY | AP ]

The team used a scout snake named Dionysus – or Dion for short – in an area of ​​the western Everglades.

“We knew he was there for a reason, and the team found him with the tallest woman we’ve seen to date.”

Biologist Ian Easterling and intern Kyle Findley helped capture the female snake and transport her through the woods to the field truck.

An autopsy also found hoof cores in the snake’s digestive system, meaning an adult white-tailed deer was its last meal.

This February 2022 photo provided by the Conservancy of Southwest Florida shows biologist Ian Bartoszek with a 15-foot female Burmese python captured while following a male scout snake in the Picayune Strand State Forest.
This February 2022 photo provided by the Conservancy of Southwest Florida shows biologist Ian Bartoszek with a 15-foot female Burmese python captured while following a male scout snake in the Picayune Strand State Forest. [ AP ]

National Geographic documented the discovery, highlighting the continued impact of invasive pythons, known for their rapid reproduction and depletion of surrounding native wildlife.

Bartoszek said culling female pythons plays a critical role in disrupting the reproductive cycle.

“This is the wildlife problem of our time for South Florida,” he said.

Since the conservation’s python program began in 2013, they’ve removed more than 1,000 pythons from about 100 square miles in southwest Florida.

During this stretch, necropsies found dozens of white-tailed deer inside Burmese pythons. Data researchers from the University of Florida have documented 24 species of mammals, 47 species of birds, and 2 species of reptiles in the stomachs of pythons.

This February 2018 photo provided by the Conservancy of Southwest Florida shows biologist Ian Easterling with a 15-foot female Burmese python captured while following a male scout snake at the Rookery Bay Estuarine National Research Reserve in Naples, Florida (Conservancy of Southwest Florida via AP)
This February 2018 photo provided by the Conservancy of Southwest Florida shows biologist Ian Easterling with a 15-foot female Burmese python captured while following a male scout snake at the Rookery Bay Estuarine National Research Reserve in Naples, Florida (Conservancy of Southwest Florida via AP) [ AP ]
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Prior to the recent discovery, the largest female removed as part of the conservation program weighed 185 pounds and was the heaviest python captured at the time in Florida, officials said.

The state’s python removal program runs for two weeks in August. Participants compete for prizes, including $2,500 for catching the most pythons.

Last year’s challenge involved more than 600 people from 25 states.

Xavier Promoted Acting Dean and Other Metropolitan College News | Crescent City Community News

XAVIER UNIVERSITY OF LOUISIANA: The new dean of the College of Arts and Sciences at Xavier University of Louisiana is Anderson Sunda-Meya, who has served as the college’s acting dean since July 2021.

LSU ENGINEERING: Steven Fletcher, a native of New Orleans, an engineering graduate student at LSU, is the recipient of the school’s Sean O’Keefe Leadership Award. Fletcher earned a bachelor’s degree in civil engineering and served as commandant of the LSU Corps of Cadets. The day before the award was announced, he was commissioned into the US Air Force. The $10,000 prize is to be used at the recipient’s discretion.

NUNEZ COMMUNITY COLLEGE: A two-day AutoCAD course will be offered from 9 a.m. to 4 p.m. on July 16 and 23 at Nunez Community College, 3710 Paris Road, Chalmette. For $300, students can learn to use an industry-standard computer-aided design program, the foundation of most design programs. To register for Nunez’s two-day AutoCAD course, go to nunez.edu/workforce/how-to-register and complete the application using CRN 30134. For more information, email email to Julie Rexford, Director of STEAM, at jrexford@nunez.edu.

LSU OGDEN HONORED COLLEGE: Among the 2022 LSU graduates who participated in the Ogden Honors College are the following scholars from the New Orleans area:

Receiving the Top Division Honor: Kia Harris of Pearl River, Psychology; and from Slidell, Alejandra Maria Ham, biological engineering, and Connor Langevin, physics.

Receive college honors:

  • André Bourque from Gretna, mathematics;
  • Kaitlin Elizabeth Couvillion de Lacombe, microbiology;
  • De Mandeville, Nicholas M Bertucci, architecture; Lauren Meyer, biological sciences; Rebecca Norton, political science and economics; Hannah Sharon Rice, music; Elizabeth Grace Stewart, finance; and Camille Wetekamm, mechanical engineering;
  • Christopher P Vasquez de Metairie, IT;
  • From New Orleans, Christopher L Hart, psychology; Peter A Howard, chemistry; Akua Lewis, English and Liberal Arts; and Jackson Vicknair, political science, English and history;
  • Abigail Brier Randolph of Pearl River, biological sciences and psychology;
  • De Slidell, Kaley Grace Pichon, music education; and Hannah M Sutton, psychology.

youNUNEZ COMMUNITY COLLEGE: Registration is open for the summer and fall semesters at Nunez Community College, 3710 Paris Road, Chalmette, and applications for institutional scholarships are accepted until July 15. Summer courses start on June 1 and fall courses on August 15. offer two abbreviated mini-sessions, which deliver full credit in half the time. For course details, visit nunez.edu/schedule.

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UMass postdoc Chan receives two fellowships to support brain research

Violeta Durán Laforet, PhD, will use a spatial transcriptomics technique to map senescent brain cells for the first time.

Violeta Durán Laforet, PhD, a post-doctoral fellow in the lab of Dorothy P. Schafer, PhD, associate professor of neurobiology, has received two grants totaling $375,000 to support her research on how brain cells affect aging.

The new funding comes from BrightFocus Foundation Postdoctoral Fellowship Program in Alzheimer’s Disease Researchwhich supports young researchers in their final stages of tutored training, and the Alzheimer’s Association Research Grantfor researchers doing work related to Alzheimer’s disease and dementia.

The Schafer lab studies how microglia regulate neural circuits in healthy and diseased nervous systems. The lab has shown that these cells are able to “eat” the synaptic connections between nerve cells to sculpt developing neural circuits and “overeat” in the early stages of neurogenerative disease to dismantle the circuits. The lab works to understand how these cells trigger and propagate inflammation in brain circuitry, with a focus on multiple sclerosis and Alzheimer’s disease.

“Microglia are the resident immune cells of the brain. They are there to protect us from different inflammatory insults such as pathogens or injuries, but they can also play a role in spreading the inflammatory process in different diseases and even in aging,” explained Dr. Durán Laforet.

Cellular senescence is a process that frequently occurs in aging in which cells stop dividing and begin to produce inflammatory mediators. With the BrightFocus award, Durán Laforet will for the first time use a spatial transcriptomics technique called MERFISH to map senescent brain cells. These cells eventually stop multiplying but don’t die when they should, continuing to release factors that can trigger inflammation.

“It has been shown that if you remove senescent cells from the brain of an Alzheimer’s mouse model, the pathology improves. In addition, senescent cells have been detected in the brains of patients with Alzheimer’s disease. So this gives us a clue that senescent cells are doing something in Alzheimer’s disease: they are damaging the brain and participating in this pathology,” said Durán Laforet.

Using technology funded by a Massachusetts Life Sciences Center grant, Dr. Schafer and Christina Baer, ​​PhD, assistant professor of microbiology and physiological systems, received in 2020, Durán Laforet will be able to take a slice of tissue and, without losing the coordinates of each cell, study the gene expression of these cells.

“Our thought is that this could be the starting point for many more studies because it has never been done. Perhaps we will discover that senescent cells are restricted to a certain area, and then we can develop new pharmacological strategies. This will allow us to target future treatments for Alzheimer’s disease and any disease with a senescent component,” said Durán Laforet.

The Alzheimer’s Association award will fund Durán Laforet’s investigation of a subset of microglia known to reside in a vascular niche. This type of microglia has been implicated in the pathogenic changes that occur in Alzheimer’s disease in blood vessels. Durán Laforet will again use MERFISH, this time to interrogate the particularities of microglia associated with blood vessels to see how they change with aging and neurodegeneration.

Durán Laforet said she has had a long interest in neurodegenerative diseases and anything related to the brain. While earning her undergraduate degree in Pharmacy from the Complutense University of Madrid, she joined the Neurovascular Research Unit, combining a new fascination for the brain with an interest in the immune system. She received her doctorate in biomedical research from the same school. During the final year of the doctoral program, she came to Massachusetts to study with Eng Lo, PhD, professor of neurology and radiology at Harvard Medical School. She came to UMass Chan in early 2021 to work in Schafer’s lab.

Related UMass Chan News Article:
Massachusetts Life Sciences Center capital funding to support three medical school programs

Husker Team Leads Effort to Help Sorghum Defend Against Aphid Attack

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Lincoln, Neb. —Each year, phytophagous pests are responsible for about 20% of crop losses worldwide.

Growers have relied on what were once considered silver bullets to manage the problem: insecticides and genetically modified plants. But while the two were successful to some extent, they failed to fully master the problem. In addition, these methods have raised various concerns: growing concern about the impact of pesticides on the environment and human health; consumer fatigue with eating chemically processed or genetically modified foods; and increasing insect resistance to many of the most commonly used pesticides.

That’s why a research team from the University of Nebraska-Lincoln is taking a closer look at an alternative method of pest control that could overcome or alleviate the problems associated with standard approaches. Entomologist Joe Louis and his collaborators recently received a grant of nearly $1.2 million from the WE Department of Agriculture to explore methods of enhancing the natural defense mechanisms of sorghum – a promising crop for food, feed and fuel – which would fortify it against sugarcane aphids, a pest that plagues the plant since 2013.

“Because pesticides stay in the environment and can affect food quality, we are thinking about how other approaches can be used,” said Louis, Eberhard Professor of Agricultural Entomology. “That’s why we started to develop the innate immunity of the plant. If we can strengthen many of these innate defenses, we can protect plants from the majority of these insect attacks in a way that may be more durable and long-lasting than current approaches.

The team also includes Tomas Helikar, Susan J. Rosowski Associate Professor of Biochemistry; Scott Sattler, assistant associate professor of agronomy and horticulture and molecular research biologist at the USDA‘s Agricultural Research Service; and Rupesh Kariyat of the University of Texas Rio Grande Valley.

The team is focusing on one of the most abundant components of plants: lignin. It plays a central role in the formation of rigid and stable cell walls and in facilitating water transport. Because the polymer is found throughout sorghum – including its outer surfaces – it is one of the first components that sugarcane aphids encounter when they insert their needle-like mouthpart into the plant.

But little is known about exactly how lignin can help sorghum repel sugarcane aphids. Louis and Sattler were intrigued by the potential defensive role of lignin when they noticed that in some sorghum plants, altered lignin levels impacted aphid behavior and the plant either became more resistant or more susceptible to the pest.

Preliminary data from these plants indicated that the monolignol pathway, which plays a key role in lignin synthesis, and a gene known as Brown midrib12, or Bmr12, located in the lignin biosynthetic pathway, could be particularly important in driving these changes.

To identify exactly how Bmr12 influences a plant’s natural immunity, Louis’ team will weave together a variety of approaches – transcriptomic, biochemical, electrophysiological, histological and computational biology. This broad and transdisciplinary approach is a major strength of the research.

“This is a holistic approach to understanding plant-aphid interactions, using multiple approaches to answer the question of how Bmr12 is involved in modulating sorghum defenses against aphids,” Louis said. “That’s how it stands out as a unique project.”

The IT component is particularly innovative. Helikar, an expert in computational systems biology, will develop a network analysis model showing how the behavior of Bmr12 has ripple effects throughout the plant. The system will allow the team to easily test hypotheses about how a change in Bmr12-associated pathways may impact a plant’s properties and defense mechanisms.

Louis and Helikar will introduce Husker students, undergraduate and graduate, to these computational approaches through new lab modules they are developing as part of the project. The new elements of the program aim to open students’ eyes to the power of interdisciplinary methods and computer modeling to solve problems in biology, entomology and ecology.

Kariyat, the University of Texas Rio Grande Valley collaborator, is leading an additional student outreach effort at a college in the Rio Grande Valley, where more than 90% of students are Hispanic. It will engage these students in inquiry-based experiments focused on plant-insect interactions.

Beyond its role in lignin production, Bmr12 can also influence a plant’s indirect defenses by producing volatile organic compounds that boost plant immunity. When certain pests attack, crops respond by producing these compounds. They strengthen plant tissues against pest damage and send airborne signals to neighboring plants, triggering their defense systems. Louis’ team will investigate how disruptive pathways associated with Bmr12 might enhance this protective mechanism.

In the long term, Louis sees work on Bmr12 as one piece of the larger puzzle of boosting natural plant immunity – there are many other genes and pathways that researchers can exploit to boost pest resistance. He does not expect natural immunity methods to completely supplant pesticides, but believes their use can be reduced to much lower levels.

“Ultimately, we hope to bring another tool to farmers that will help them reduce the use of toxic insecticides,” he said.

The research is funded by the Plant Biotic Interactions Programa joint initiative of the USDAfrom the National Institute of Food and Agriculture and the National Science Foundation.

‘Joy of learning’: Top La Jolla high school graduates share words of wisdom for college aspirants

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As La Jolla High School grads threw their caps in the air this month, campuses recognized their top students, who gave their classmates a little advice.

A common lesson – GPA doesn’t matter as much as doing what you love.

The Episcopal School

Alexandra Midler was the highest grade point average at La Jolla’s The Bishop’s School.

(Courtesy of Alexandra Midler)

The Bishop’s School Harvard Cup is awarded annually to the senior with the highest GPA. This year, Alexandra Midler finished the first semester with a mark of 5.01.

Midler said the award was “icing on the cake for high school. …Valedictorian was never my goal.

“I worked hard because I loved my classes,” she said. “I always want to learn something as much as possible to understand it as best as I can.”

Midler, who will next head to Stanford University to study biology and creative writing, said those hoping to emulate her valedictorian success should “take courses you find interesting and work hard for that joy. to learn and create”.

“High school is something to savor,” she added. “You should enjoy the whole experience, not just think about an end goal.”

Joseph Aguilar won the Bishop School's Michael W. Teitelman Loyalty Cup.

Joseph Aguilar won the Bishop’s Michael W. Teitelman Loyalty Cup, awarded to a senior who demonstrates loyalty, excellence, and integrity.

(Studio M / Courtesy of Bishop’s School)

Joseph Aguilar won the Michael W. Teitelman Loyalty Cup from Bishop’s, given to a senior who demonstrates loyalty, excellence and integrity in all aspects of student life.

The honor surprised Aguilar, who said, “I’m really grateful.”

Reflecting on his time at Bishop’s, Aguilar said, “I invested myself in everything I did. Bishop’s gave me so many opportunities and things to try out and get excited about,” from improv shows to creating a barbershop quartet to volunteer programs.

“I was so ready to take advantage of it… and really see what I could do,” he said, in addition to “investing myself in my studies to get the most out of my classes.”

Aguilar advised those following a similar path to “do what makes you happy” and take advantage of what school has to offer.

Aguilar will now head to Yale University as a computer science and arts major.

La Jolla Country Day School

Khalil Desai won the La Jolla Country Day Administrators Award for achieving the highest cumulative GPA in the promotion.

Khalil Desai won the La Jolla Country Day School Administrators Award for achieving the highest cumulative GPA in the graduating class.

(Courtesy of Khalil Desai)

Khalil Desai won the La Jolla Country Day School Administrators Award for achieving the highest cumulative GPA in the class with a 4.8.

Although Desai said GPA is an “outdated metric [and] not a great measure of academic potential or skill,” he added, “it was a lot of work and it took a lot of time, so in the end I’m proud of myself.”

Desai, who will be attending Brown University in the fall to study biology, said those who put weight on GPA should “always take the toughest courses that will give you [a] quality bump” and apply consistently.

“Most… people could do it,” he said.

Sohan Chunduru won the La Jolla Country Day Principal's Award for achieving the second-highest cumulative GPA.

Sohan Chunduru won the La Jolla Country Day Principal’s Award for achieving the second-highest cumulative GPA.

(Courtesy of Sohan Chunduru)

Sohan Chunduru won Country Day’s Principal’s Award for achieving the second highest cumulative GPA with a 4.77.

Chunduru, who will go to Stanford to study political science or public policy, said he didn’t expect such a high ranking, but “I worked pretty hard in college, so it’s good to knowing that it paid off.”

“Interest in a variety of subjects helps keep you motivated to work hard in school,” he added.

He advocated for young students to maintain a “good balance between school and life in general, because if you spend all your time studying it will end up being worse for your mental health”.

La Jolla High School

La Jolla High School valedictorian Dagny Whall said earning the highest honor with a 4.92 GPA “is exciting to see all the hard work pay off.”

Whall said she and Salutatorian Andrew Park and third-place finisher Leon Wang pushed each other “to do our best and work with each other rather than against each other.”

The three often collaborated while studying, Whall said.

Becoming valedictorian seemed “out of reach” early in high school, Whall said. But “as it crept in, it became more of a possibility. I think that definitely helped motivate me in the end.

Whall, who will enroll at Georgetown University in the fall to study computer science and economics, advised students entering high school to find subjects they like and try to progress as much as possible. .

“That way you’re not only good at what you do, but you also enjoy the time you spend doing it,” she said.

Rob Tindall, her math teacher at Muirlands Middle School, had a positive impact on her, teaching her to cope with stress and to “deal with something when you don’t understand it and move on”, she said.

“We applied that in math, and then I apply that in the rest of my life,” Whall said.

Park, who had a 4.9 GPA, said earning the rank of salutatorian was “a byproduct of the courses I wanted to take. It wasn’t really a goal I was actively pursuing.

Rather, he said, his GPA reflects “how I wanted to be challenged.”

Park advised future top GPA hopefuls to ‘devalue the GPA [and] focus more on courses and experiences that make you happy.

“Just looking at GPA as the end goal is, I think, a very naïve and dangerous construct that people can fall into because at the end of the day often the GPA ranking doesn’t reflect the students who have worked the hardest,” he said. . “It’s something that leans heavily towards people who prefer and thrive in an academic setting.”

Park will go to Princeton University to study economics, applied mathematics and politics.

Wang, La Jolla High’s third GPA winner with a 4.8, echoed Park’s thoughts that “the GPA is definitely not the most important thing.”

“If you have to prioritize one thing or another, then you should do your own hobbies,” he said. “A lot of people think you have to do certain things to look good on your college application, like nonprofits or research, but there are a lot of things like…side things you like that can also work.”

Wang now plans to study biology at Dartmouth College. ◆

P. Jeremy Wang: Professor Emeritus to President Ralph L. Brinster at Penn Vet

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P. Jeremy Wang: Professor Emeritus to President Ralph L. Brinster at Penn Vet

Andrew M. Hoffman, Gilbert S. Kahn Dean of the University of Pennsylvania School of Veterinary Medicine (Penn Vet), has named internationally recognized reproductive biologist P. Jeremy Wang, Professor Emeritus to President Ralph L. Brinster.

Dr. Wang holds an extraordinary record of scholarly achievement. His research program focuses on the cellular, molecular, genetic and epigenetic controls of meiosis, the cell division process specific to germ cells and which influences genetic diversity. Dr. Wang seeks to understand the generation of gametes by meiosis in vitro, which could remedy infertility in animals and humans; it also seeks to identify abnormal meiosis, which can lead to spontaneous pregnancy loss or human congenital conditions. He received NIH support totaling $16 million at Penn and is currently a principal investigator on two NIH grants. He has mentored over 28 students and fellows from across the United States and around the world.

“Dr. Wang’s scientific work has been published in more than 60 peer-reviewed publications in high-impact journals,” said Ellen Puré, chair of the Department of Biomedical Sciences and Grace Lansing Lambert Professor of Biomedical Sciences. outstanding achievements have earned him numerous awards, including the prestigious Society for the Study of Reproduction Research Award. Dr. Wang has published articles in journals such as Nature Genetics, Science Advances, Genes & Development and Nucleic Acids Research. He is very sought after by editorial boards and grant review committees, and as a presenter at over 50 invited and nominated conferences.

Dr. Wang received his MD from Peking University Health Science Center and his PhD in Molecular Biology and Genetics from Cornell University. After a postdoctoral fellowship with David C. Page at MIT’s Whitehead Institute in Cambridge, Massachusetts, Dr. Wang joined Penn Vet’s Department of Biomedical Sciences in 2002 as an Assistant Professor of Developmental Biology. His career progressed from Associate Professor, Professor, and then Director of the Center for Animal Transgenesis and Germ Cell Research. Dr. Wang is also a faculty member of the Center for Reproductive and Women’s Health Research at Penn’s Perelman School of Medicine and the Penn Institute for Regenerative Medicine.

“The President Ralph L. Brinster Emeritus Professorship was for a distinguished reproductive scientist who embodies the passion, rigor, and pioneering spirit of Dr. Ralph Brinster, our distinguished faculty member in the same field of study and winner of the National Medal of Science,” said Andrew Hoffman, Dean of Veterinary Medicine Gilbert S. Kahn. “Dr. Jeremy Wang personifies these qualities and as such he was selected from among his peers, both here at the University and around the world, to fill this illustrious position. I am delighted to have him in our faculty.

The award of an appointed and endowed faculty position is the highest honor bestowed on a faculty member at the University of Pennsylvania and reflects a commitment to scientific discovery, mentorship, and service. Established in 2017 through a gift from former Penn Vet Board Member Henrietta Alexander, the President Ralph L. Brinster Professor Emeritus Chair was named in honor of Dr. Brinster, Richard King Mellon Professor of Reproductive Physiology from Penn Vet.

Dr. Cato T. Laurencin, first of UConn elected to Academia Europaea

Dr. Cato T. Laurencin is the first professor from the University of Connecticut to be elected to the Academia Europaea for his outstanding achievements as a scholar, as well as his scholarship and eminence in his field. Membership of the Academia Europaea is by invitation only after peer nomination and competition.

“I am very honored to be elected to this Academy. This further shows how important the field of regenerative engineering is to the world and its ability to deliver game-changing results aimed at helping people,” said Laurencin, University Professor at UConn and Albert and Wilda Van Dusen Professor Emeritus of orthopedic surgery at the UConn School of Medicine. .

This year, in addition to being honored by the Academia Europaea, six additional academies around the world have elected Laurencin over the past 9 months: the European Academy of Sciences, the Senegalese Academy of Sciences and Techniques, the Beninese Academy of Sciences and Arts, the Indian Academy of Sciences and the Royal Academy of Engineering.

Laurencin is also CEO of the Connecticut Convergence Institute for Translation in Regenerative Engineering at UConn Health and Professor of Chemical Engineering, Materials Science and Engineering, and Biomedical Engineering at UConn.

Laurencin’s fundamental and singular achievements in the fields of tissue regeneration, biomaterials science, nanotechnology and regenerative engineering, a field he founded, made him the greatest engineer-physician- researcher in the world. His groundbreaking achievements have resulted in transformative advances in improving human life. His fundamental contributions to materials science and engineering include the introduction of nanotechnology in the field of biomaterials for regeneration.

Laurencin received singular honors in engineering, medicine, science and technology for his work. He is the first individual in history to receive both the National Academy of Engineering’s oldest/highest award (the Founder’s Simon Ramo Award) and one of the oldest/highest awards from the National Academy of Medicine (the Walsh McDermott Medal). The American Association for the Advancement of Science presented Laurencin with the Philip Hauge Abelson Award given “for his outstanding contributions to the advancement of science in the United States.” He is the recipient of the National Medal of Technology and Innovation, America’s highest honor for technological achievement, presented by President Barack Obama during ceremonies at the White House.

In recognition of his groundbreaking achievements in the field of regenerative engineering worldwide, the American Institute of Chemical Engineers established the Cato T. Laurencin Regenerative Engineering Founder’s Award.

The Academy is the pan-European Academy of Humanities and Letters. Academy members are scientists and scholars who collectively aim to promote learning, education and research. Founded in 1988, with over 5,000 members, including leading experts in the physical sciences and technology, biological sciences and medicine, mathematics, arts and humanities, social and cognitive sciences, economics and law. The Academy also publishes the international journal The European review.

The Academia Europaea advances and propagates excellence in research in the humanities, law, economics, social and political sciences, mathematics, medicine and all branches of natural and technological sciences throughout the world for the public good and for the advancement of the education of the public of all ages in the above subjects in Europe. The Academy comprises seventy-two Nobel laureates, several of whom were elected to the Academy before receiving the award.

“I would like to congratulate you on having passed the process of electing members by competition,” wrote Marja Makarow, president of the Academia Europea in her award letter to Laurencin.

Laurencin’s election to the Academy will be honored at its October 2023 annual conference in Munich.

Call to delay clinical trials for gel stroke treatments

June 20, 2022 — Clinical trials of new freeze treatments for stroke should be delayed until the technology used in the tests improves, according to research conducted at the University of Strathclyde.

The researchers say failure to do so could have ‘devastating’ effects on the outlook for treatments used for strokes and other conditions.

Stroke currently lacks treatments, in part because, so far, stem cell therapies cannot be used for chronic strokes.

The gels have the potential to be an effective stroke treatment, due to their ability to fill brain cavities created by strokes and their ability to interact with glial scars, a type of scar that forms in the cavity area and seals it. from the rest of the brain.

The gels could also be effective in delivering the drug and stem cell payload, thanks to unique properties that can be tailored to the requirements of a specific stroke site.

But no clinical trials have so far been successfully commissioned to explore the potential of regenerative gels for the treatment of chronic stroke. This was partly because preclinical laboratory studies did not consider the full range of ages and health conditions of stroke patients.

Researchers reviewed more than 90 research papers from the past five years, focusing on five types of gels with potential for use in stroke, and found this to be a ‘bottleneck’ in development new therapies. The authors recommend that studies come to a better understanding of how gels interact with human stroke tissue, as well as the effects of increasing gel volume on the size of stroke patient cavities. .

The study was published in the journal Trends in biotechnology.

Dr Hilary Carswell, a reader at the Strathclyde Institute of Pharmacy and Biomedical Sciences, is the lead author of the study. She said: “Stroke is a huge unmet clinical need and there is an urgent need to move to new treatments. There has been success in some preclinical trials of gels but our research has identified knowledge gaps that need to be filled before clinical trials can proceed.

“Stroke often has many co-morbidities, such as hypertension, diabetes and obesity, but the gels offered have not yet been tested against these conditions. A stroke cavity can be as large as 50 cm3 preclinical research must therefore be extended to the size of the human brain.

“Gels have a lot advantages but we need to get these things worked out before they can move into clinical trials and be translated into treatments.

The study also involved King Abdulaziz University in Jeddah, Saudi Arabia.

The authors say: “We urge a postponement of the commissioning of clinical trials to minimize the risk of poor performance in the early stages of trials. While this is frustrating given the overall slow progress in developing stroke therapies, the importance of successful gel-based clinical trials cannot be underestimated. If unsuccessful, premature gel-based clinical trials could have devastating effects on the future of these technologies, both in stroke and in broader regenerative applications.

“Therefore, in order to maximize the future of regenerative gels and realize their full potential, a careful approach is needed to ensure their success when they finally enter the clinic.”

Stroke is one of the leading causes of death and disability worldwide. In about 85% of cases, stroke is caused by an ischemic event due to a blockage of blood supply to the brain.

For more information: www.strath.ac.uk

We need biology in the fight against climate change. But are we ready to use it?

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The following article is an opinion piece written by Markus Gershater. The views and opinions expressed in this article are those of the author and do not necessarily reflect the official position of Technology Networks.

If we do not act, climate change will cause untold suffering. Biology is one of the most powerful technologies available and could play a huge role in the fight. But our ability to work with it is insufficient. What can we do about it?

We are often told that we should do more as individuals to help save the world. Refuse plastic straws, turn off lights, use less water and donate to plant trees. All good stuff, but it feels like trying to stop a tidal wave with a paper umbrella. Although we mean well, the temperature keeps rising; what good is a plastic-free straw when the world is on fire? The scale of the challenge can be paralyzing, but we must find a way out of these comforting placebos.

Here’s my belief: we can’t even rely on business leaders or governments to make enough change to avert disaster, let alone individuals. The kind of climate change impacts that would force the emergency on these groups will only happen once it’s too late, once too much CO2 is in the atmosphere.

Our safest bet in the climate fight? Transformative technology solutions. For many, that means wind, solar, electric vehicles, nuclear fission and, one day, fusion. But there is a sleeping giant we are not talking about. It’s one of the most powerful phenomena we know of: it can connect the nano to the macro, spin tall trees out of gas and light, and coordinate huge flows of energy and matter in space. amazing variety of life we ​​see on our blue planet. . With her on our side, the odds change in our favor. But we don’t know how to use it. Not yet.

This sleeping giant? Biology.

Problem 1: It is not easy to store energy

The story of climate change is a story of energy. Really renewable energy needs efficient storage. For biology, it’s simple: it can pack energy into dense packets of carbon-carbon bonds just by being exposed to sunlight. Although renewable energy is better than non-renewable energy, the best places to Craft that energy is often not localized where people need this energy. There is a lot of sun in the desert, but few people.

But imagine a world where renewable electricity is stored in biological hydrocarbon-based systems. Compact and emission-free, they can be shipped wherever they are needed. Imagine a teeming forest providing all the jet fuel we could ever need or a living floating island that heats homes far away in the deepest tundra.

Problem 2: Current power consumption is way too high

Humans do a lot of energy-intensive things. After energy production itself, agriculture is the second largest carbon emitter. Producing meat is particularly bad, but cultured meat or meat substitutes would be an improvement. Making nitrogen fertilizers tells the same story, but if we created crops that could fix their own nitrogen, that would be transformative.

What about engineering plants to enhance photosynthesis? It’s not out of the realm of possibility. Plants have evolved for eons and photosynthesis for even longer than that. But it did not evolve under the conditions that we can offer plants today. In a piece of engineering, biologists have increased photosynthetic efficiency by 40%. On a larger scale, this could pave the way for more efficient agricultural production and fix atmospheric CO2 In the process.

Problem 3: No way to sequester carbon on a large scale


The number one enemy in the fight against climate change is, as we all know, carbon. Ever since our species discovered combustion, we have spent carbon to buy energy. Today, we use energy to extract carbon from the atmosphere. Biology has been doing this for 3.4 billion years and is a clear candidate to roll back our gaseous vandalism of the past 200 years.

How would we do this on a large scale? Maybe it’s huge seas of algae, dense plantations creating carbon-based products, or bioprocesses producing bricks with the strength of seashells to trap carbon in our buildings in the form of calcium carbonate. .

We are close to fixing these issues, but not quite yet

If some of these ideas seem fanciful, it’s not because biology doesn’t have the ability to make them happen. No way. The real problem is our inability to understand biology well enough to turn these ideas into reality. We live in an era before the approaching era of true biological mastery. When our species reaches this threshold, however, our progress to date will be “the early days.” Although our biotechnological progress is accelerating, it is not fast enough. Not yet.

But I have good news: there is huge potential for improvement in the way we conduct biological experiments. Although biology seems infinitely complex, our experiments are usually planned in Word documents, carried out with hand pipettes and analyzed in spreadsheets. These are 20th century ways of solving 21st century problems. The gap between the challenge of biological engineering and the tools we use is huge, but it’s a gap we can bridge.

Cloud-based computing, AI, and automation are commonplace in other industries. They have the most to offer when it comes to the intricacies of biology: powerful experiments conducted using automation can produce the datasets scientists will need to gain unimaginable insights. When we bring AI into the mix, the power of human ingenuity will be unleashed to design a myriad of biological solutions. We’ll fix the carbon, do more with less, and combine it all with renewable energy sources to ensure we can support our global population without destroying the natural world.

We have a long way to go. Success is far from certain. But, if we can get biology on our side, we have a chance for an incredible future to unfold.

OPKO Health acquires ModeX The

  • Dr. Elias Zerhouni, President of ModeX, Former President of Global R&D at Sanofi and Former NIH Director, Named President and Vice President of OPKO
  • Dr. Gary Nabel, Chairman and CEO of ModeX, Former Chief Scientific Officer of Sanofi, and Founder of NIH’s Vaccine Research Center, Joins OPKO as Chief Innovation Officer and OPKO Board Member
  • Alexis Borisy, Independent Lead Director of ModeX and Leading Biotech Entrepreneur and Investor, Joins OPKO Board of Directors

The transaction will be discussed on OPKO’s Q1 2022 conference call today at 4:30 p.m. ET

MIAMI, May 09, 2022 (GLOBE NEWSWIRE) — OPKO Health, Inc. (OPK), a multinational biopharmaceutical and diagnostics company, today announced the acquisition of ModeX Therapeutics, Inc., a private biotechnology company focused on the development of innovative multi-specific immune therapies for cancer and infectious diseases. OPKO acquired ModeX for $300 million in OPKO common stock.

Founded in October 2020 with headquarters in Natick, Mass., ModeX Therapeutics has developed highly flexible multispecific antibody technology platforms with broad targeting and functional capabilities, simpler manufacturing, and potentially better specificity and safety, offering significant differentiation from competing platforms. The design of these multi-species lends itself to gene-based delivery by mRNA or DNA vectors. The ModeX product portfolio includes cancer immunotherapies that combine four specificities into a single protein to enhance immune targeting and killing, as well as masking or “stealth” technology to enhance tumor-specific killing and reduce side effects. For viral diseases, prime targets for a broad and potent portfolio of multi-specific antibodies include HIV and SARS-CoV-2. A vaccine against the Epstein-Barr virus is also under development.

“The acquisition of ModeX Therapeutics significantly expands our technology base and expands our product portfolio to include multi-functional, multi-specific antibodies focused on a range of cancers and infectious diseases, with applicability to other therapeutic areas. We believe that the promise of better outcomes for patients treated with these multispecific antibodies represents a new generation of large molecule therapies and the next chapter for OPKO,” said Phillip Frost, MD, President and CEO of OPKO. “We welcome ModeX co-founders Dr. Zerhouni and Dr. Nabel, as well as Alexis Borisy to our Board of Directors, and Dr. Zerhouni and Dr. Nabel to the leadership team of ModeX. ‘OPKO. The ModeX leadership team brings to OPKO a wealth of industry experience, knowledge and contacts, which we believe will have a significant long-term positive impact on OPKO as we advance their technology and pipeline. of products and that we will take advantage of potential synergies with our current diagnostics and therapeutics portfolio.”

Elias Zerhouni, MD, co-founder and chairman of the board of ModeX, has been named chairman and vice chairman of the board of OPKO. Dr. Zerhouni brings extensive experience in academia, government, and industry as a leading authority on emerging trends and issues in medical care and biomedical research and development. A physician-researcher with an academic background in imaging and biomedical engineering, Dr. Zerhouni most recently served as President of Global Research and Development and Executive Vice President of Sanofi. Dr. Zerhouni has also served as Director of the National Institutes of Health (NIH), Senior Fellow for Global Health Research at the Bill and Melinda Gates Foundation, U.S. Presidential Envoy for Science and Technology, and Professor and Department Chair Russell H Morgan. of Radiology and Biomedical Engineering, Executive Associate Dean and Dean of Research at Johns Hopkins School of Medicine. Dr. Zerhouni was elected to the National Academy of Medicine and the National Academy of Engineering. He serves on the boards of the Lasker Foundation, Foundation for NIH, Davos Alzheimer’s Collaborative, and Research!America. He received the Scripps Executive of the Year Award 2017 for the pharmaceutical industry and the French Legion of Honor in 2008. He has been a director of Danaher Corporation since 2009.

“Being part of OPKO represents a transformational opportunity for both companies. We anticipate this will accelerate ModeX’s product pipeline focused on unmet needs in oncology and infectious disease and the development of our innovative technologies, and also leverage leveraged synergies with OPKO’s programs,” said Dr. Zerhouni. “ModeX has been running smoothly since our inception 18 months ago based on more than 10 years of prior groundwork. We have assembled a team of world-class management with exceptional leadership experience in the public and private sectors to advance our programs.Our lead drug candidate is already in the clinical phase while several others in late preclinical phase are expected to enter clinical development in 2023. We have were prompted to join OPKO by the vision and enthusiasm of his leadership to enhance our mutual potential to breakthrough innovation.

Gary Nabel, MD, Ph.D., co-founder, president and CEO of ModeX, has been named Chief Innovation Officer of OPKO and joins the OPKO Board of Directors. Dr. Nabel, a renowned virologist and immunologist, was Chief Scientific Officer and Senior Vice President of Sanofi, where he led the groundbreaking laboratory that developed tri-specific products currently in early clinical development. He is the founding director of the NIH Vaccine Research Center, working on vaccines and broadly neutralizing antibodies against HIV, influenza, SARS, Ebola, Chikungunya, and the Epstein-Barr virus. He was previously a researcher at the Howard Hughes Medical Institute at the University of Michigan. In recognition of his cutting-edge expertise in virology, immunology, gene therapy and molecular biology, Dr. Nabel has been elected to the National Academy of Medicine, is a Fellow of the American Association of Physicians and from the American Academy of Arts Sciences, and was awarded the Geoffrey Beene Builders of Science Award from Research! America.

Alexis Borisy, Independent Lead Director of ModeX, also joins OPKO’s Board of Directors. Mr. Borisy is a leading biotechnology entrepreneur and investor with over 25 years of experience, including serving as founder, CEO and/or Chairman of nine NASDAQ-listed companies. He co-founded and served as CEO or President of Blueprint Medicines, Foundation Medicine, Relay Therapeutics, Tango Therapeutics, Celsius Therapeutics and CombinatoRx.

With the addition of Dr. Zerhouni, Dr. Nabel and Mr. Borisy to the board of OPKO, the number of directors increases to 13.

Conference Call and Webcast Information

Management will discuss this transaction and answer questions during the company’s previously scheduled first quarter 2022 conference call, which will be held today at 4:30 p.m. EST. Participants can pre-register for the conference call using this link. Callers who pre-register will receive a unique PIN code to immediately access the call and bypass the live operator. Participants can register at any time, including up to and after the call start time. Those unable to pre-register can participate by dialing (866) 777-2509 (U.S.) or (412) 317-5413 (International). A webcast of the call can also be viewed on OPKO’s Investor Relations page and here.

A phone replay will be available through May 16, 2022 by dialing (877) 344-7529 (U.S.) or (412) 317-0088 (International) and providing passcode 6587528. A replay on Web will be available approximately one hour after the live conference call ends here.

About OPKO Health, Inc.

OPKO is a multinational biopharmaceutical and diagnostics company that seeks to establish industry-leading positions in large, fast-growing markets by leveraging its expertise in the discovery, development and commercialization of new and proprietary technologies. . For more information, visit www.opko.com.

Caution Regarding Forward-Looking Statements

This press release contains “forward-looking statements”, as that term is defined in the Private Securities Litigation Reform Act of 1995 (PSLRA), which statements may be identified by words such as “expects”, “plans “, “plans”, “will”, “may”, “anticipates”, “believes”, “should”, “intends”, “estimates”, and other words of similar meaning, including statements re product development efforts as well as other non-historical statements, including statements about our expectations, products, beliefs or intentions regarding the ModeX acquisition, projected future clinical developments, synergies, benefits and opportunities of the transaction, the potential of ModeX’s products and pipeline and any other statements regarding OPKO’s and ModeX’s expectations, beliefs, plans, product candidates, objectives, financial terms, assumptions or future events or performance . Many factors could cause our actual operations or results to differ materially from the operations and results anticipated in the forward-looking statements. These factors include those described in our annual reports on Form 10-K filed and to be filed with the Securities and Exchange Commission and under the heading “Risk Factors” in our other filings with the Securities and Exchange Commission. In addition, forward-looking statements may also be affected by general market factors, competitive product development, product availability, federal and state regulations and laws, regulatory process for new products and indications, manufacturing issues that may arise, patent positions and litigation. , among other factors. The forward-looking statements contained in this press release speak only as of the date on which they were made, and we undertake no obligation to update any forward-looking statements. We intend that all forward-looking statements be subject to the safe harbor provisions of the PSLRA.

contacts:

LHA Investor Relations
Yvonne Briggs, 310-691-7100
[email protected]
Where
Bruce Voss, 310-691-7100
[email protected]

Opko-Health-Inc-.png

Why You Should Watch ‘Jurassic World Dominion’

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India was undergoing immense brewing in the 1990s. The early years of the decade were when Coke and Pepsi appeared on market shelves and computer centers proliferated.

In 1993 came jurassic park. The film redefined cinema, bringing prehistoric animals to life in spectacular fashion. People were fascinated. It was a surreal realization of computer graphics; a genre never before seen in action.

The film showed fictitious, advanced DNA technology that most likely appeared to be true.

Since then, many movies have come with much more advanced infographics and even an overkill.

But what makes jurassic park special is the philosophy behind it.

Michael Crichton (1942-2008) was an extraordinary storyteller. It would be surprising if readers knew that his novel Male Terminal (1972) was translated and serialized in the popular Tamil magazine of the 1970s Kumutham and was a smash hit with readers.

It was about how a medical effort to control human behavior with a neural implant “brain stimulator” goes haywire.

Her 1990 novel jurassic park also revolves around the same theme but in more detail.

Later he wrote a sequel, The lost World (1995). It centered around the character of mathematician Ian Malcolm who presents himself as the voice of the holistic approach in jurassic park.

His statement that “life finds a way” is a fairly unofficial philosophical statement of Crichton’s worldview.

Michael Crichton (1942-2008)

The two novels jurassic park and The lost World provide readers with some of the basic concepts of theoretical and systems biology, particularly regarding evolution.

They also raise questions of bioethics and show us how a great power can create disruptions in the complex connected ecosystems that make up the planetary process we call Earth.

Essentially, both novels are tales of caution and also motivation to understand the phenomenon called life, with respect and humility. The philosophical core of Jurassic Park is expressed through the delirious words of the mathematician character Ian Malcolm who deserves to be quoted in detail:

It is also one of the central problems of the appropriation of knowledge.

The first film was faithful to the spirit and values ​​of the author. Now in 2022, 29 years after the first Jurassic Park movie and 14 years after Crichton’s death, we have Jurassic World Dominion, directed by Colin Trevorrow.

It’s a world where the failed Jurassic Park experiment had dumped its genetically resurrected and manipulated dinosaurs into the world and prehistoric animals, through their own evolutionary pathways, settle for a new kind of balance.

Then there is corporate greed and the evil side of human depravity. These create corporate genetic control of the planet’s food chain on one side and an underground illegal trade in dinosaurs on the other (dinosaur meat wet markets to velociraptor battle rings).

Then, a human-dinosaur relationship also evolves based on a kind of empathy.

Telling the whole story here isn’t the plan; see it for yourself, but you get the picture of the world the plot unfolds in, don’t you? Essentially, it’s about corporate greed to manipulate genomes versus the ongoing chaos that thwarts control-based science. In other words, the storyline is the same as in the original. jurassic park but on the scale of a planet and that with improved graphics as well as our new knowledge on the dinosaurs.

The movie brings new dinosaurs for sure. There are Giganotosaurus (not Gigantosaurus as commonly misspelled. It’s Giga as in Gigabytes) as apex predator. Here is how National Geographic News reported the discovery of their fossils:

Giganotosaurus is the apex predator of

Giganotosaurus is the apex predator of “Jurassic World Dominion”

There are also feathered dinosaurs in the movie.

In 1996, a Chinese farmer Li Yumin, who was also a part-time fossil hunter, discovered a fossil slab from the Chinese province of Lianoing. It was sold to a museum. Phil Currie of the Tyrrell Museum in Alberta, who was touring the fossils in Mongolia, recognized the importance.

When this became known to the Chinese government, it banned all photos of the fossil and a team of Chinese scientists began working on it. Until their article was published, there would be no photographs.

In the same year, Chinese scientists published the article in a Chinese museum journal. Appointed Sinosauropteryx (Chinese lizard wing), the fossil has become something of a climactic piece of evidence to settle the raging debate over whether birds evolved from dinosaurs.

Dinosaurs had feathers.

Feathered dinosaurs have become part of common paleontological knowledge. The current paleontological conclusion is that even velociraptors had feathers.

Sinosauropteryx fossil plate

Sinosauropteryx fossil plate

This is just a glimpse of how the movie franchise has updated with scientific discoveries – better than how our textbooks update. What is needed is the passionate urge to bring science to children and ignite their brains with the need to explore. It’s a shame that our textbook makers lack what even the Hollywood industry has.

There are other significant changes to the film franchise. (Here the two sequences of jurassic park and others following jurassic world movies are not taken into account.)

One is how velociraptors are depicted. In the original film, they were portrayed as packs hunting cruel predators. In fact, in the first movie, there seemed to be an underlying assumption – herbivorous dinosaurs are good, carnivorous dinosaurs are bad. Even the facial features of the former were shown pleasing, and a gratuitous cruelty emanated from the way the raptors and Tyrannosaurus rex were shown.

In reality, the species depicted in the original jurassic park has been Deinonychus antirrhopus, also known as Velociraptor antirrhopus, who inhabited what is now America.

In the 2022 movie, the velociraptors seem to understand humans and the human characters are made to sympathize with the velociraptors, almost like in the old Indian miracle movies where the snakes seem to hear and understand what the humans are saying.

The film also talks about the mother-child bond and the care of velociraptors. This may seem quite overkill. Although we don’t yet have such evidence for velociraptors in general, fossil evidence shows varying levels of parental care. Studying the behavior of the closest dinosaur descendants like ostriches shows remarkable parental care for newborns.

More important is how quickly we transform by expanding our empathy. What was a hideous monster in 1993 has become an animal that humans sympathize with.

Oviraptor 83 million years ago: 'ya devi sarva bhuteshu Matru rupena...'

Oviraptor 83 million years ago: ‘ya devi sarva bhuteshu Matru rupena…’

It’s sort of a reflection of the same trend in science as well. When the first oviraptor fossil was discovered in 1922 near what appeared to be the fossilized eggs, thought to be the stolen eggs of another dinosaur species, protoceraptos. Therefore, the given name meant “egg thieves”. But now we know the fossil was actually a relative.

In fact, a superb fossil discovered in the Gobi desert in 1994 shows a oviraptor spread over her nest of eggs. The skull was missing. She brooded or guarded her eggs just like today’s birds. She was ready to sit on the eggs and face disaster rather than maybe run. Perhaps she was as “selfless” as any mother protecting her offspring.

The fossil, now in a Mongolian dinosaur museum, is a reminder of ‘Ya Devi Sarva Bhuteshu Matru Rupena …’. This has been a claim that is as true for at least some dinosaur species as it is for branches of modern mammalian life, including humans.

The new film is full of the usual cliches – the corporate villain manipulating nature through the control of reductionist technology, the dinosaurs still killing the bad guys while still missing the good guys, and the USA-centric approach. However, it remains the best film to date to introduce your children to the fascinating world of dinosaurs, evolution and ecology.

The film ends with a plea for coexistence and mutual respect for all life, with a silhouette of elephants and dinosaurs moving together, minutes before we leave the room.

Personally, I can only wonder if the mahout-elephant relationship is not one. Nowhere else has such a majestic animal been integrated with such love and respect into human culture and life. Although vilified today by fashionable wildlife enthusiasts, and despite some systemic course corrections it requires, the elephant-mahout relationship in the traditional Hindu ecosystem provides a classic example of a historical demonstration of a such coexistence and such mutual respect.

National Geographic Photo: Photograph by Mohit Midha

National Geographic Photo: Photograph by Mohit Midha

Coexistence in mutual respect with the infinite variety that evolution produces is a fundamental value of Hindu civilization and today its importance is impressively underlined through such popular films, despite their clichés and obsession centered on United States.

Fish and Game officials remind recreational shooters that it is illegal to target protected non-game birds and protected ground squirrels

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The temperatures are starting to climb and the days are getting long, and that’s good news for recreational shooters looking to get out of the city limits to shoot some guns. Summer is a popular season for recreational shooters statewide, but it’s also a critical time of year for some nongame bird species that nest or are commonly found in popular shooting areas.

While the majority of recreational hunters and shooters obey the law, Fish and Game law enforcement officials remind shooters that they are likely to encounter protected wildlife and there is a heavy price to be paid. pay to pull the trigger on a protected species.

Two men recently pleaded guilty to illegally taking a golden eagle (a protected bird of prey) from the Morley Nelson Snake River National Birds of Prey Conservation Area. A judge sentenced the two men to two years probation, as well as a two-year hunting and firearms ban. Each had to pay restitution of more than $3,000.

It’s the shooter’s responsibility to know the law, and a good rule of thumb is to shoot targets rather than wildlife unless you know exactly what you’re shooting at and are doing it legally.

“Illegal shooting of protected nongame wildlife such as owls, hawks, eagles and other birds such as long-billed curlews is a persistent and widespread problem in Idaho,” said Deniz Aygen, Fish and Game Observable Wildlife Biologist. “Long-billed Curlews and many species of raptors are identified by Fish and Game as species most in need of conservation, and unfortunately significant poaching is occurring in areas that have been established to aid in their conservation, but are also heavily used by recreational shooters.

Almost all non-game bird species found in Idaho are protected and therefore illegal to shoot. There are a few non-native species that can be caught year-round with a valid hunting license, including European starlings, Eurasian collared doves, house sparrows, and rock pigeons.

Shooting protected birds may seem harmless, but it has been shown to affect some bird populations.

Research published in 2020 shows that the shooting of protected non-game species – particularly raptors and long-billed curlews – is more common in areas of high use by recreational shooters and occurs more frequently than previously thought. thought before.

Where was the study conducted? In southwestern Idaho in the Morley Nelson Snake River National Birds of Prey Conservation Area.
The study suggested that illegal shooting may have a role in the long-term declines observed for the local long-billed curlew population in the conservation area, which had declined from over 2,000 in the late 1970s to less than 200 in 2014, and now has well under 100 curlews.

The study also implied that a small segment of recreational shooters appear to poach protected nongame species while they target or hunt unprotected nongame species like ground squirrels.

A note on ground squirrels

At this time of year, many shooters target ground squirrels throughout the state. Although there are a few species of ground squirrels open to hunting, such as the Uinta or Columbia ground squirrel, some ground squirrels are protected. For example, northern and southern Idaho ground squirrels, rock squirrels, Piute ground squirrels (in eastern Idaho), Merriam ground squirrels, golden-mantled ground squirrels, and ground squirrels in Wyoming (in southwestern Idaho) are all protected species and should not be targeted.

If you can’t tell the difference between an unprotected and a protected species of ground squirrel, or any other wild animal, you shouldn’t target them.

Check Fish and Game’s ground squirrels webpage for a complete list of protected and unprotected ground squirrel species before heading out.

People can help preserve Idaho’s hunting and fishing heritage by reporting poaching. Make the call if something doesn’t seem right. Contact Citizens Against Poaching at 1-800-632-5999.

Maine biologists are giving loons space this nesting season / Public News Service

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Maine is home to the highest number of loons in the region and it is nesting season.

The Maine Loon Restoration Project is a five-year effort to limit threats to the breeding chances and survival of loons. They place loon nesting rafts on Maine lakes where breeding pairs haven’t hatched chicks in three years. The goal is to place 100 rafts by 2026.

Earl Johnson, loon restoration biologist for Maine Audubon, said loons are sensitive to disturbance, especially during nesting season.

“It can be a really, really stressful time in a loon’s life, and getting close to them on a boat or in the water doesn’t help the loons at all,” Johnson explained. “They are sensitive to disturbance and truly amazing to observe, but from a safe distance is better for everyone.”

He added that they are starting a “Loon Rangers” program to educate and raise awareness about loon nesting grounds, so people can avoid these areas by boat or personal watercraft. The project also includes Fish Lead Free programs to reduce the use of lead tackle, a common cause of death among loons.

In 2003, a spill leaked 98,000 gallons of oil into Buzzards Bay, killing hundreds of loons over the next few years.

Jill Marianacci, another loon restoration biologist for Maine Audubon, said Mainers love loons and communities enthusiastically got involved in the project, funded by the 2017 settlement following the spill.

“It’s nesting season right now,” Marianacci pointed out. “All the lakes and ponds that we’ve put rafts on, we’re starting to see what pairs are going to those rafts, and hopefully in a couple of weeks we’ll see if they’re successful in hatching chicks, which is very exciting.”

Maine Audubon leads the Loon Restoration Project in partnership with the Penobscot Nation, Maine Lakes and Lakes Environmental Association.

They are looking for volunteers to help with outreach, education and statewide management. Bird watchers can take part in the annual loon count on Saturday, July 16.

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Caltech Grad to Washington, D.C. on Fisher Fellowship

Geophysics graduate student Oliver Stephenson, who will graduate next month, will travel to Washington, D.C., in September on a William L. Fisher Congressional Geoscience Fellowship to help policymakers base their decisions on solid scientific data.

Oliver Stephenson

The fellowship lasts for one year, and Stephenson intends to use this opportunity to help launch a career in science policy, working with government officials to ensure science informs decision-making. He plans to use the scientific training he received at Caltech to try to make the world a better place in the most direct way possible.

“I’ve always been interested in connecting with people and having a positive impact on the world,” Stephenson says. “But the pandemic has shown me how science can and should be used to make the best decisions, and what happens when science isn’t used. You see the huge inequalities in outcomes.”

A geophysicist by training, Stephenson’s main areas of science policy interest are climate change mitigation, natural hazard preparedness and response, and how artificial intelligence (AI) will shape society.

Although AI might seem out of left field for a geophysicist, Stephenson took a course in 2019 called CMS270 – Advanced Topics in Computing and Mathematical Sciences, which connected scientists with AI experts. In the course, Stephenson helped develop a method for mapping collapsed buildings after natural disasters. The class was created by Richard Murray, Thomas E. and Doris Everhart Professor of Control Systems and Dynamics and Bioengineering and William K. Bowes Jr. Executive Chair in the Division of Biology and Biological Engineering; and Eric Schmidt, co-founder of Schmidt Futures and former executive chairman of Alphabet Inc.

Once in Washington, Stephenson will meet with United States Senators, Representatives and others. After receiving internship offers, he selects one and gets to work, either in a legislator’s office or on a committee assigned to work on a specific issue. Stephenson says he hopes to spend the next year learning how Congress works and how it can positively impact the world by working with Congress leaders.

“In government, you need people with their hearts in the right place, people who are held accountable, and people who have the best information,” Stephenson said. “I want to make sure they have that information.”

Funding for the scholarship is provided by an endowment established by the AGI Foundation to honor William L. Fisher, Leonidas T. Barrow Centennial Professor and Chair Emeritus of Mineral Resources at the Jackson School of Geosciences at the University of Texas at Austin. More information can be found on the American Geosciences Institute website.

Guthrie Symposium brings together researchers and families to discuss advances in newborn screening

1982 photo of Dr. Robert Guthrie checking up on a baby who benefited from Guthrie's work.

Robert Guthrie, known as the “Father of Newborn Screening,” checks out one of the infants who benefited from his work in this 1982 photo. Courtesy of the UB Archives.

Release date: June 16, 2022

Allison Brashear MD MBA;  Dean Jacobs School of Medicine and Vice President of Health Sciences;  Department of Neurology;  Jacobs School of Medicine and Biomedical Sciences at the University at Buffalo;  2021.

BUFFALO, NY – Within days of birth, babies around the world experience a quick needlestick in the heel. The resulting drop of blood is used to detect up to 50 genetic conditions so that, if detected, they can be treated from birth.

Widely recognized as one of the most cost-effective and successful public health advances of the last century, this simple procedure was developed in Buffalo by Robert Guthrie, MD, PhD, while he was a faculty member at the University at Buffalo and physician at John R. Oishei Children’s Hospital from 1958 to 1986. Guthrie developed the blood test to screen for the genetic condition called phenylketonuria (PKU) in newborns. Today, dozens of genetic diseases are detected from this single drop of blood.

On June 28, UB and Oishei will present the Robert Guthrie Colloquium 2022 to honor his legacy and provide a forum where renowned genetic researchers and families affected by PKU and other genetic diseases can discuss the latest advances and future advancements. Register online by visiting the UB Alumni site.

Buffalo’s Profound Contribution to Genetics

Taosheng Huang, MD, PhD, Division Chief of Human Genetics, Department of Pediatrics, Jacobs School of Medicine and Biomedical Sciences.

“Everyone in the field of clinical genetics knows of Dr. Guthrie’s profound contribution to this field,” said Taosheng Huang, MD, PhD, professor and head of the division of genetics in the department of pediatrics at Jacobs School of Medicine. and Biomedical Sciences at UB.

“With this annual event, we would like everyone to know what UB, Oishei and Buffalo have contributed to this field, recognize the impact of Guthrie’s work on science and medicine, and discuss the rapid advances that are happening now. said Huang, who is also medical director of genetics and metabolism at Oishei, program director of clinical cancer genetics at Great Lakes Cancer Center, and physician at UBMD Pediatrics.

Recruited to UB and Oishei in 2020 from Cincinnati Children’s Hospital Medical Center, Huang is an expert in mitochondrial disease genetics, neonatal and prenatal screening and diagnosis. He pioneered breakthrough innovations in the detection and treatment of genetic diseases, including the potential to prevent the transmission of genetic mutations to the fetus using a technique known as mitochondrial replacement therapy.

“Here at Oishei Children’s Hospital and Jacobs School of Medicine and Biomedical Sciences, we are thrilled to build on Dr. Guthrie’s legacy under Dr. Huang’s leadership and innovative research,” said Stephen Turkovich. , MD, Chief Medical Officer of Oishei Children’s. Hospital and Clinical Assistant Professor in the Department of Pediatrics at the Jacobs School

“Over the next decade, we anticipate significant advances in the field of neonatal genetics and newborn screening. These advances will particularly benefit the hundreds of babies admitted to our Level IV Neonatal Intensive Care Unit each year,” Turkovich said.

Open to healthcare providers, families, researchers and community stakeholders, the free event will include presentations, keynotes and panel discussions, and feature KSL Robert Guthrie Laboratories, offering new and expanded.

“We are very proud to honor the life and legacy of Dr. Guthrie, the ‘Father of Newborn Screening’, whose groundbreaking work at UB and Oishei Children’s Hospital saved thousands of lives. around the world,” said Allison Brashear, MD, vice president of health sciences at UB and dean of the Jacobs School, who will deliver the keynote address.

“This significant event and the recruitment of Dr. Huang to Buffalo demonstrate our shared commitment to continuing the newborn screening revolution founded by Guthrie.

Major clinical trial on a cure for PKU

A clear example of this commitment is the new clinical trial Huang will soon lead in Buffalo to test a gene-editing therapy developed by Homology, Inc. that could cure PKU with a single injection.

Held in person and remotely, the one-day symposium will provide a forum where leading physicians and researchers in the field of genetic and metabolic disorders will share the latest advances in research and clinical practice.

Research topics to be discussed include the state of newborn screening in Europe and developing countries; optimize neonatal screening and therapies for metabolic diseases; a genetic medicine approach to curing PKU; and new research from UB to improve newborn screening for Krabbe disease, which claimed the life of Buffalo Bills quarterback Jim Kelly’s son and others.

An essential ingredient of the forum is the opportunity for families affected by genetic diseases to come together, with world-renowned researchers and with suppliers who provide the nutritional formulas that many of these children depend on for their daily nutritional needs.

“What we live on a daily basis”

Staci and Eddie Kaspryzk had never heard of PKU. But when their daughter Norah was just six days old, they discovered she had tested positive for the genetic condition. Since that day, more than seven years ago, the family has gone through what all families with a genetic disease go through: a massive effort to understand the disease and come to terms with what it means day in and day out.

Along with sharing critical information with other families and learning about cutting-edge research, Kaspryzk says one of her goals in attending Guthrie’s symposium is simply to raise awareness.

“Most people have never heard of it, or if they’ve heard of PKU, they think that once you’re on the right diet, that’s all there is to it” , she says. “But it’s not just dietary, it’s much more involved. I just wish people would start to understand what we live with on a daily basis.

Like many metabolic diseases, PKU is caused by a genetic mutation that prevents the body from breaking down food properly. If the disease is not detected by newborn screening, it can quickly lead to irreversible brain damage, intellectual disability and neurological crises.

Kaspryzk explains that children and adults with PKU cannot consume more than a few grams of protein per day; she adds, for example, that a single ounce of pasta contains 8 grams. The diet must be precisely controlled; most of the PKU diet consists of nutritional formulas, which must be taken at specific times of the day. She notes that even a small variation in the schedule or the amount consumed can create physical and emotional problems for the child.

She is now a board member of the Mid-Atlantic Connection for PKU and Allied Disorders, whose goal is to increase awareness of PKU and related disorders, and to highlight the importance of diagnosing these disorders at the birth.

His advice to families who are just finding out their child has PKU or another metabolic disorder is, “I would say just take it a day at a time. It’s extremely overwhelming when you first enter this community, but it’s totally manageable and the community is amazing.

She adds that Huang’s presence in Buffalo and the revival of clinical genetics research in the region are a tremendous boon. “Dr. Huang has brought so much to our clinic for PKU and genetics,” she says.

“I hope in my lifetime and I know in my daughter’s lifetime there will be a big breakthrough or a cure. There is so much more hope now than just seven years ago when Norah was born. It’s extremely exciting.

Media Contacts

TEACHx Symposium returns in person with the theme “Reconnect”

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Popular Northwestern University TEACHx symposium, spotlighting innovative experiences in teaching and learning, returned to an in-person event this year. More than 200 faculty, graduate students, learning designers, and education technology specialists attended TEACHx 2022 last month at the Norris University Center to learn from their peers.

This year’s theme was ‘Reconnect’, with a dual focus on teaching with technology and teaching for diversity, equity and inclusion. Dozens of experts from the Northwest and beyond discussed various teaching methods developed during the pandemic, including how remote and in-person teaching experiences have informed each other.

To kick off the day, neuroscientist Mays Imad delivered the keynote address, “Beyond Theory: Witnessing as an Act of Love, Resistance and Healing”. In his talk, Imad discussed the power of knowledge and how understanding the neuroscience of toxic stress can empower instructors to self-regulate and help students cope, engage, connect and learn.

Imad is an assistant professor of biology at Connecticut College. She is also a Fellow of the Gardner Institute and a Senior Fellow of the American Association of Colleges and Universities in the Office of Undergraduate STEM Education.

Thesessions that followed Imad’s speech included a mix of presentations, panels, workshops and pre-recorded videos. Topics ranged from mentoring in the age of the pandemic and video in the online classroom to designing flexible courses and creating a culture of digital inclusion and accessibility. The one-day event ended with a networking reception.

As Northwestern moves away from distance learning, it is vitally important that we understand the student and faculty experience during this time,” said Victoria Getis, director of teaching and learning technologies at Northwest Information Technology.

“The innovations we’ve seen will shape our ‘next normal’ for our classrooms, both physical and digital,” she said. “TEACHx is also an opportunity to pay tribute to the incredible work our instructors have done under very difficult circumstances and to celebrate their achievements..”

One of this year’s highlights came at noon when three instructors were inducted into the inaugural class of the Northwestern Canvas Hall of Fame. Nominations came entirely from students and fell into one of three categories: most innovative course site; Better use of conference videos/recordings; and Excellence in DEI/Accessibility.

Over 660 individual nominations were received for 360 instructors from the 12 North West schools. The winning instructors are:

  • Katie Gesmundo, Teaching Assistant Professor of Chemistry and Co-Director of the General Chemistry Lab, Weinberg College of Arts and Sciences, for Most Innovative Course Site
  • Ilya Mikhelson, Teaching Associate Professor of Electrical and Computer Engineering, McCormick School of Engineering, for the best use of lecture videos/recordings
  • Ray Noll, Affiliate Professor, SPAN Postdoctoral Fellow (2020-22) in the Gender and Sexuality Studies Program, Weinberg College, for Excellence in DEI/Accessibility

Organized for the first time in 2016, TEACHx takes place every year and is a collaboration between Northwest Information Technology and the Provost’s Office. It aims to develop avenues of connection and collaboration in a variety of learning environments.

Gimv strengthens its position in life sciences venture capital with the creation of a new dedicated platform

Gimv AG

Gimv is getting stronger his position in life sciences capital risk with the creation of a new dedicated platform

  • Trim-out of New Life sciences Platform of Gimv’s Existing health Platform

  • Bbuilt on Gimv’s more … than 40 years of experience of successful investis lying in the area

  • ambition of grow the life sciencess Venture capital portfolio to about twenty companies, from 12 p.m. today

  • In line with Gimv commitment to continue to invest in innovative research and badded value for society, the patients and shareholders

  • Bram Vanparys* appointed Managing Partner, Head of Life Sciences

Antwerp, BelgiumJune 15, 2022: Gimv (Euronext – GIMB), a European investment company, listed on Euronext Brussels, with 40 years of experience in private equity and venture capital, announces the creation of its fifth investment platform focused on venture capital investments in innovative life science ventures.

Following strong growth within Gimv’s existing healthcare platform, a dedicated life sciences platform will strengthen Gimv’s role in the international ecosystem of life science venture capital firms. The main investment objective remains the search for solutions to the many unmet health care needs.

The Life Sciences platform builds on the success and excellent returns generated by portfolio companies over four decades, including companies like Ablynx, where Gimv was a founding investor and Covagen, which was acquired by Johnson & Johnson . Current investments include Precirix, ImCheck and ImmunOs, which recently raised $74m in a Series B funding round led by Gimv.

With this new platform, Gimv can further strengthen its ability to invest larger tickets, with a typical initial investment of EUR 10-15 million per company. With the aim of nearly doubling its current portfolio to around 20 companies, Gimv will maintain its Series A and B investment strategy with a particular focus on drug development. Other areas of investment will include medical technology, digital health, life science tools and agri-biotechnology.

Bram Vanparys*, who was a partner in the Gimv Healthcare platform, has been appointed to lead the new team of seven venture capital professionals dedicated to life sciences, which will be further expanded over the next few years.

Koen Dejonckheere, Cchief Eexecutive Oofficer of Gimv, commented: “In addition to our existing four investment platforms Sustainable Cities, Smart Industries, Consumer Goods and Healthcare, our new Life Sciences platform will allow us to build on Gimv’s strong track record of investments in life sciences. . Furthermore, it will help strengthen our position at the forefront of the European life sciences ecosystem, recognized globally for its innovation and excellence in the development of life-saving therapies.

Bram Vanparys*, Manager Partner and Boss of Life Sscience at Gimv, said: “The launch of the new Life Sciences platform represents an exciting new step for Gimv in the sector. We will be able to focus more of our efforts on providing venture capital to companies with promising new therapies for patients. Together with the rest of the team, I look forward to this new chapter for Gimv.

bart Diels**, Managing Partner and Head of Healthvsare at Gimvadded: “After building a strong portfolio within the Healthcare platform, the time has come to launch a focused Life Sciences platform. Having a VC-centric Life Sciences platform separate from a PE-centric healthcare platform allows for greater focus for both teams while preserving potential synergies. We believe that our specialized approach, supported by an experienced team, is one of the main differentiators of Gimv’s investment strategy. I am proud of what we have accomplished together over the past few years and have great confidence in Bram and his team to further strengthen our Life Sciences franchise.

contacts:

Gimv
Bram Vanparys*
Email: Bram.Vanparys@gimv.com
Such. : +32 3 290 21 00

Consilium Strategic Communications
Amber Fennell, Lucy Featherstone
E: Gimv@consilium-comms.com
T: +44 (0)20 3709 5700

Notes to Editors

Afight gimv
Gimv is a European investment company, listed on Euronext Brussels. With 40 years of experience in private equity and venture capital, Gimv currently has €2 billion in assets under management. The portfolio comprises approximately 60 portfolio companies, with a combined turnover of 3.1 billion euros and more than 18,000 employees.

As a recognized market leader in selected investment platforms, Gimv identifies entrepreneurial and innovative companies with high growth potential and supports them in their transformation into market leaders. Gimv’s five investment platforms are Consumer, Healthcare, Life Sciences, Smart Industries and Sustainable Cities. Each platform works with a team experienced in Gimv’s home markets of Benelux, France and DACH, supported by an extensive international network of experts.

Further information about Gimv is available at www.gimv.com.

* Acting on behalf of Root bv

** Acting on behalf of Candor Consult bv

Black student makes history after graduating from USask biomedical neuroscience program – News

“My friend said, ‘You realize you’re one of the first black female students and one of the first black women (in the program),'” Magbadelo said. “I was like ‘Wow.’ At that point, I really realized that I was potentially making history, and that was a huge wake-up call.

Magbadelo was one of the first black students to graduate from the new biomedical sciences degree program at this year’s University of Saskatchewan (USask) Spring 2022 Convocation. She also earned a minor in psychology.

When she realized she was also one of the first black women to graduate from the program, Magbadelo reflected on the moment.

“It’s encouraging and motivating to be an example for other women of color to just give it a shot,” Magbadelo said. “You’d be surprised at how many opportunities you have, but you can overthink it or undermine your value.”

Magbadelo’s interest in biomedical sciences began in high school biology – specifically the brain and heart.

When applying for post-secondary programs in 2018, Magbadelo was looking for direct-entry programs that matched her interest in learning more about the functions of the brain and heart. After moving from her hometown of Calgary, Alberta, Magbadelo was first accepted to USask for the Pharmacology and Physiology program until the new Biomedical Science programs opened in 2020.

“I said to myself: ‘I will take my chance and I will apply for a transfer.’ And the funny thing is, I applied the day before the admission deadline because I was too focused on not getting in because there were 40 places available for neuroscience.

She quickly learned that she was accepted into the program and over the next two years, with the program undergoing some changes, Magbadelo graduated.

The revamped biomedical science programs are a partnership between the College of Arts and Sciences and the College of Medicine. The updated program began in May 2021, with the goal of providing cutting-edge multidisciplinary training that will position students for careers in the biomedical sciences and health professions.

Now that she’s graduated, Magbadelo is ready to enter STEM (science, technology, engineering, and math) fields.

“It was overwhelming at first,” she said. “But once I crossed the stage, I realized that the real work starts now. And I have to do something to make an impact in society.

Magbadelo wants to work in the field of clinical neuroscience, possibly as a clinical laboratory technician specializing in neurological disorders.

“My main goal is to really be involved in research and innovation to find diseases and treatments related to neurology,” she said.

Magbadelo offered advice for other black women and people of color considering applying to biomedical sciences and/or other STEM fields.

“The #1 thing is not to underestimate yourself,” she said. “You are more talented than you think. High expectations of yourself can push you (to excel), but at the same time, it can also cause you to question yourself. So, be your best critic but also your biggest supporter.

Mother whales choose nursery sites in shallow water where predators cannot “eavesdrop” on the communication between a mother and her calf.

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Sitting on a beach facing the sea, it might seem unusual to spot one of the world’s largest animals swimming in shallow coastal waters 30 feet deep. But each winter, female southern right whales migrate thousands of miles to bay habitats to give birth and care for their young. So why do they choose such shallow nurseries that can be in dangerous proximity to human activity and where the food supply is scarce?

While researchers have speculated that whales up to 50 feet long choose these spots due to the lack of predators and warmer, calmer waters, a team of biologists from the Bioacoustics Lab and Behavioral Ecology from Syracuse University recently discovered a potential new pattern. They hypothesize that shallow, sandy, near-shore waters are a prime location for whales to give birth and raise their young because these areas have reduced acoustic propagation, meaning vocal signals do not travel. far away at these sites, allowing mother whales to communicate with nearby calves, unheard by predators in the distance.

Since questions remain as to why baleen whales migrate such long distances each year, the research team says their findings shed new light on their migratory behavior. Understanding habitat use and selection also allows researchers to better target conservation and management efforts, which is essential for endangered whale species like the right whale in the North Atlantic.

Authors Julia Zeh and Julia Dombroski, both PhDs. candidates in biology at the College of Arts and Sciences (A&S), and Susan Parks, associate professor of biology and principal investigator of the bioacoustics and behavioral ecology laboratory at A&S, collected data from three nurseries on three continents in the southern hemisphere (South America, Africa and Australia) where southern right whale nurseries are often observed. In their article published in Royal Society Open Sciencethey found that the depth at which right whale mothers and their calves are often observed has the most limited acoustic detection range for their calls.

“Animals that communicate using sound must balance the need to be heard by their target audience against the risk of being overheard by prying eyes such as predators,” says Zeh.

Modifications of sound-producing behavior to reduce detectability by eavesdroppers are known as acoustic encryption. Southern right whales have commonly used three forms of acoustic encryption to avoid predators: reduced call amplitude; use signal frequencies that are difficult for eavesdroppers to detect and/or locate; and reducing or completely stopping the production of acoustic signals, effectively becoming silent to avoid detection.

In their paper, the team proposes a fourth method of acoustic encryption centered on the habitat choice of southern right whales.

“We found that mothers and southern right whales spend time in specific places where they can hear each other, but other animals cannot hear them,” says Zeh. “These findings follow some interesting recent papers that recorded silent calls, or essentially whispers, from mothers and right whale calves.”

Future research will aim to determine to what extent a habitat selection approach may be common to acoustic crypsis.

Source of the story:

Material provided by Syracuse University. Original written by Dan Bernardi. Note: Content may be edited for style and length.

Chimeric Antibody Market Outlook, Development, Applications, Verticals, Strategies & Forecasts, Opportunities in 2021-2027, Key Player-Aviva Systems Biology – Instant Interview

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By key players: Aviva Systems Biology Biorbyt Biotem Creative-BiolabsEnCor Biotechnology Inc. – ImmuQuest – Jackson ImmunoResearch Laboratories – MABTECH – OmniAb Technology – WILEX Inc.

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SpaceX must meet environmental requirements before launch in Texas — FAA

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SpaceX can proceed with planned orbital launches of its Starship vehicle from Texas provided Elon Musk’s company makes dozens of environmental adjustments, the Federal Aviation Administration announced Monday.

Driving the news: An FAA environmental review found there would be “no significant impact” to the Gulf Coast region from SpaceX’s launches from its Boca Chica site.

Screenshot: SpaceX/Twitter

Yes, but: The FAA said SpaceX must take more than 75 steps to mitigate environmental impacts.

The big picture: Requirements include closing a nearby highway and Boca Chica beach during launches. “Closures will not be permitted on the 18 identified holidays” and will be limited to five weekends per year, according to an emailed statement to the FAA.

  • SpaceX must work with a “qualified biologist” on lighting inspections to minimize impact on sea turtles, conduct quarterly local beach cleanups, help with education and conservation efforts in the area.
  • The company is also required to make contributions of $5,000 a year each to groups that protect endangered ocelots and birds of prey, among other measures.

What they say : “Environmental review must be completed with public safety, national security, and other analyzes before a decision on whether to grant a launch license can be made,” the FAA said.

  • “The license application is still pending.”

The bottom line, via Miriam Kramer of Axios: SpaceX now has the opportunity to gain full approval to launch its Mars rocket from its preferred launch site.

Go further… Elon Musk: There’s a 70% chance I’ll personally go to Mars

Biologist suspects avian flu as cause of alarming number of dead birds found on New Brunswick coast – New Brunswick

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Biologist Lewnanny Richardson has never seen the amount of dead birds he has seen in the past three weeks on the coast of the Acadian Peninsula during his 22-year career.

The director of the Species at Risk program at Nature NB, a conservation-focused nonprofit, said in an interview Monday that he first noticed a large amount of dead gannets while surveying Facterie-à-Bastien beach as part of his research on piping plovers at the end of May.

“The first day we saw three (dead birds). The next day we saw 22 of them on a two kilometer beach. After that he started getting big numbers like 100 and 150,” he said.

He said that while he is not yet concerned about the impact this will have on the large gannet population, he is alarmed by the sheer volume of dead birds he has seen in such a short time. .

The story continues under the ad

After studying the strange behavior of a live gannet he encountered, he suspects bird flu is to blame.

Read more:

Avian flu in Canada: everything you need to know

“I even saw birds that I had never seen in my life, like the common murre,” he says.

“The last time we were on the beach I could count 20. So imagine, I’ve never seen them in 22 years and I’ve seen 20 dead on the same day.

He said the province’s Department of Natural Resources cleaned up 196 dead birds from the beach on Friday. Monday morning, he only observed three or four dead birds.

“Usually you see a lot of gannets flying every day, (Monday) morning there were none. It’s not usual,” he said.


Click to play the video:







New Brunswick poultry farmers concerned about avian flu


New Brunswick poultry farmers concerned about avian flu

The province’s Department of Natural Resources declined an interview with Global News, instead sending a statement saying the public should report sightings of dead birds to their department, which will deal with them on a case-by-case basis.

The story continues under the ad

While avian flu has been a regular concern for poultry farmers since it emerged in Canada in the 1960s, Lisa Bishop-Spencer, communications director for Chicken Farmers of Canada, said this strain is of particular concern because there are currently cases active in eight provinces, which has never happened before.

Read more:

“Canadians should be very concerned about their food supply,” says New Brunswick farmer

She said in an interview Monday that this iteration of bird flu is highly pathogenic.

“So if it enters the barn in a highly pathogenic form, it can wipe out a herd very quickly,” she explained.

Farmers across the country are taking extra precautions, such as locking down their farms and rigorously cleaning all incoming vehicles.

These additional measures can create difficulties as farmers already face additional costs such as rising fuel prices.

“Financially, it’s very stressful for (farmers). What they’re trying to do is avoid the added stress of foraying into their current farm, so it’s worth taking all the necessary steps.

However, she said Canadians need not worry about eating poultry.

“The odds of (bird flu infected chicken) ending up in the food stream are extremely low and if it did, just cooking it would kill (the virus),” she said.

© 2022 Global News, a division of Corus Entertainment Inc.

Current Biological Oxygen Demand (BOD) Cylinders Market Status and Future Outlook (2022-2029) – DWK Life Sciences, Environmental Express, Hach, Eisco Labs, United Scientific Supplies, Glassco, witeg Labortechnik, SCP SCIENCE, Changzhou Putian Instrument Manufacturing – Indian Defense News

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North West Scheduler Response Session – Times News Online

Published on June 12, 2022 at 3:30 p.m.

Lehigh Northwestern School District to Host Three-Day Active Law Enforcement Shooter

Intervention course (LASER) from June 14 to 16.

Training will take place at Northwestern Lehigh High School and is conducted by the LSU National Center for Biomedical Research and Training/Academy of Counter-Terrorist Education using Department of Homeland Security certified instructors and curriculum.

This course covers the technical aspects of planning and implementing a rapid deployment of law enforcement during an active shooter incident through classroom presentations, hands-on field training performance-based and scenario-based hands-on exercises. Future trainings will include the Integrated Active Threat Response course which teaches integration between law enforcement, fire and emergency medical services in

active shooter events and the Critical Decision Making for Complex Coordinated Attacks course.

The training is coordinated by the Northwestern Lehigh School Police Department. In addition to everything

participating NWLSPD officers, attendees will include Pennsylvania State Police officers,

Upper Macungie Police Department, South Whitehall Police Department, Lehigh County Sheriffs, as well as

School Police Officers, Northern Lehigh School District, Carbon-Lehigh Intermediate Unit, Lehighton

School District, Panther Valley School District and Shikellamy School District.

Questions should be directed to Chief Brian Tobin at tobinb@nwlehighsd.org.

Questions about LSU NCBRT/ACE can be directed to Kris Wartelle at kwartelle@ncbrt.lsu.edu or training@ncbrt.lsu.edu.

.

The biggest gaming news for June 11, 2022

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Here we are in the middle of another weekend, or as I like to call it, an uninterrupted two-day gaming session. I’ll let you get back to your game, but we need to go through the news first. Today we learned that a biologist was studying Pokemon, the actor playing Master Chief in the Halo TV series wanted to reinterpret the character, and Pokemon Red & Green was supposed to have 65,000 different versions instead of just two. There’s more where that came from and so read on for the rest.

RELATED: What Are TheGamer Staff Playing This Weekend?

Pablo Schreiber Says His Role In Halo Was To “Sever” The Viewer’s Relationship With Master Chief

The actor behind Master Chief in the Halo TV show, Pablo Schreiber, seems to have played the role a bit against expectation on purpose, in order to change the way viewers think of the character. “The process of the first season kind of broke that relationship that people had with Master Chief, of knowing him and acknowledging him as themselves,” Schreiber said. “We knew going into it that this was going to be a slightly uncomfortable experience for many viewers due to how long they’ve been living with this Master Chief paradigm. But the idea is, for a long-running television series, I hope the discomfort of the first season and the breaking of the paradigm will pay off in the long run in the relationship you’ll have with these kind of the most iconic video game characters of all time, i imagine Master Chief was a role difficult to play from the start.

GAME VIDEO OF THE DAY

Biologist shows what Pokémon could look like under the skin

I never wondered what kind of organs a Pokémon would have, but the question seems to have troubled a certain biologist by the name of Christopher Stoll who put together some scientific illustrations with disturbing results to say the least. Stoll put them on Reddit just to “spoil your week”. Mission accomplished.

Sega is already planning “more games like Sonic Frontiers”

Fans of the franchise have given mixed messages about the upcoming Sonic Frontiers. While a few like what they see, many have called the game “embarrassing” and even asked for a delay. The developer behind the game, Sega, plans to push even further with its open-world design despite the controversy. “Sonic fans from 30 years ago are now adults. There are also young fans who may have started with the movies and such,” explained Sonic Team Leader Takashi Iizuka. “Going forward, we want the Sonic brand to appeal to both groups in its games and other media. Part of that is our June release of Sonic Origins. It’s a perfect representation of Sonic’s origins for fans, old and new. Iizuka added that “we also plan to create more games like Sonic Frontiers that will delight 3D Sonic veterans in new ways. Our plan is to target these specific groups of Sonic fans with each of our upcoming releases.”


Morbius fans demand to bring the film back a third time

Morbius may have been a box office flop, but that didn’t stop its producer, Columbia, from releasing the film a second time. What I’m just going to call fans of the film seem to have pumped Morbius on social media before quickly dumping the film when it was back in theaters. The result was of course a second flop. The latest development is people trying the same tactic, noting that “we were all busy this weekend” and calling on Columbia to “bring Morbius to the theater a third time,” according to a grassroots petition. I wonder how many times can a film fail?

Pokemon Red & Green Was Originally Supposed To Have 65,000 Versions Rather Than Two, Focus On Buying Instead Of Catching Pokemon

Video game historians have sifted through dozens of old interviews with the people who produced the original Pokemon games. Their findings were rather surprising as it turns out that Pokemon Red & Green was originally supposed to have over 65,000 different versions instead of just two. The game was also supposed to be about buying instead of catching Pokémon. “The shape of a forest, the Pokémon that would appear, I wanted to make a game that would be different for everyone, but it was difficult,” said Game Freak founder Satoshi Tajiri. “So I went to consult Shigeru Miyamoto from Nintendo and we ended up deciding that depending on the color, whether it was red or green, the worlds would be parallel, but different.” The developer also stated that “in early development of Pokemon, you could buy Pokemon with money, but this caused the player to focus on saving money to buy them and less motivation to fight for them. catch them in the wild”. It really changed everything.


NEXT: Niantic’s Own Steam Build Campfire May Fix Pokemon Go Raid Issue

Biologists complete spring netting on Flaming Gorge Reservoir

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Biologists are still concerned about the number of small lake trout in the reservoir after completing the annual spring net fishing ritual.

GREEN RIVER – Green River Fisheries Biologists from the Wyoming Game and Fish Department recently completed the annual spring netting at Flaming Gorge Reservoir and are still concerned about the number of small lake trout in the reservoir.

For this reason, they are encouraging anglers to register for the Hell on Reels Fishing Derby sponsored by Buckboard Marina on June 11-12. The contest is a multi-species contest with multiple categories for lake trout under twenty-five inches that will be fun and challenging for entrants to win.

“Overall lake trout catch rates have increased this spring by 25% compared to 2021, this is partly due to an increase in the number of lake trout over twenty-eight inches sampled this year,” according to fisheries biologist John Walrath “The majority of small lake trout caught were from the north end of the reservoir – north of Brinegar to the confluence. The average size of lake trout caught increased by about four inches and overall the body condition of trout caught has also improved since 2021.”

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“The majority of small lake trout caught were from the north end of the reservoir – north of Brinegar to the confluence,” Walrath continued. “The average size of lake trout caught has increased by about four inches, and overall the body condition of trout caught has also improved since 2021.”

“Many of the lake trout sampled along the shore strongly preyed on newly stocked rainbow trout. Lake trout made up 50% of all fish sampled in shoreline sets. that we caught more rainbow trout and cutthroat trout from Bear River,” Walrath said.

Fisheries managers have encouraged the harvest of small lake trout or calves for several years due to concerns about the abundance of small lake trout and the impacts that large numbers of small predators have on wild and stocked salmon and stocked trout.

Fisheries supervisor Robb Keith said: ‘It is well documented in western fisheries that lake trout under 25 inches can consume a lot of juvenile trout and salmon, especially when their numbers get very high. The abundance of small lake trout is the reason that fisheries managers have increased the bag limit and possession limits for small lake trout and continue to encourage participation in fishing derbies that encourage the targeting of small lake trout.

Anti-TSG6 Antibody Market Growth at CAGR of 73.0%, Fitzgerald Industries International (US), Origene (US), Lifespan Biosciences (US), USBiological (US) – Indian Defense News

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New Jersey, United States – The TSG6 Antibody The market report includes the upcoming challenges and opportunities in the market. It ensures a strengthened market position and a growing product portfolio by providing all the important details related to the market growth. It reveals some of the key insights and focuses on the impact of the COVID-19 crisis on different sectors of the economy. Identifying key business areas is the single most important factor in improving those areas and generating greater profits. This living market research provides an in-depth understanding of how new product offerings can fit into the market. It acts as the best guide and plays the leading role in almost all phases of the business cycle. It also becomes easy to effectively target customers to easily launch new products. This TSG6 Antibody Market reports another key focus is to provide manufacturing solutions at all provincial and global levels.

Some of the major companies influencing this market include:

Thermo Fisher Scientific (USA), Aviva Systems Biology Corporation (USA), Abbexa Ltd (UK), Boster Biological Technology (USA), Biobyt (UK), Genetex (USA), Fitzgerald Industries International (USA), Origene (USA), Lifespan Biosciences (USA), USBiological (USA)

A comprehensive overview of market conditions and various business-related elements is covered in this TSG6 Antibody Market research report. It enables business actors to reach target groups and provides all important details about customers and competitors. Quantitative research methods are used to conduct this market research to provide accurate market data and problem solving. The TSG6 Antibody Market report helps to identify major regions such as Asia-Pacific, North America, Europe, Middle East, Africa, and Latin America where new players and merchants can expand their business. Moreover, it performs in-depth analysis and provides market size, market dynamics, and market share.

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Various factors are responsible for the growth trajectory of the market, which are studied extensively in the report. In addition, the report lists down the restraints that threaten the global TSG6 Antibody market .This report is a consolidation of primary and secondary research, which provides market size, share, dynamics and forecasts for various segments and sub-segments considering macro and micro environmental factors. It also assesses the bargaining power of suppliers and buyers, the threat of new entrants and product substitutes, and the degree of competition prevailing in the market.

ATTRIBUTES

DETAILS

ESTIMATED YEAR

2022

YEAR OF REFERENCE

2021

FORECAST YEAR

2029

HISTORICAL YEAR

2020

UNITY

Value (million USD/billion)

SECTORS COVERED

Types, applications, end users, and more.

REPORT COVER

Revenue Forecast, Business Ranking, Competitive Landscape, Growth Factors and Trends

BY REGION

North America, Europe, Asia-Pacific, Latin America, Middle East and Africa

CUSTOMIZATION SCOPE

Free report customization (equivalent to up to 4 analyst business days) with purchase. Added or changed country, region and segment scope.

TSG6 Antibody Market Types:

Above 90%, Above 95%, Above 99%, Others.

TSG6 Antibody Market Applications:

Biopharmaceutical companies, hospitals, bioscience research institutes, others

The report studies the key segments of the global TSG6 Antibody industry, their growth over the past few years, the profiles and market size of the individual segments, and provides a detailed overview of the profiles of the various segments. The report also presents the key products and various other products of the global TSG6 Antibody industry along with its market size and growth over the study period. The key drivers of demand for the products and services of the global TSG6 Antibody industry are outlined in the report. The TSG6 Antibody report details some major success factors and risk factors related to investing in certain segments.

The report provides information about the following pointers:

Market penetration: Comprehensive data on the product portfolios of major players in the TSG6 Antibody Market.

Product Development/Innovation: Detailed information on upcoming technologies, R&D activities and product launches in the market.

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Market Diversification: Detailed data on new products, untapped geographies, recent advancements, and investment opportunities in the TSG6 Antibody market.

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Key questions covered in this report?

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Contents

Global TSG6 Antibody Market Research Report 2022-2029

Chapter 1 TSG6 Antibody Market Overview

Chapter 2 Global Economic Impact on Industry

Chapter 3 Global Market Competition by Manufacturers

Chapter 4 Global Production, Revenue (Value) by Region

Chapter 5 Global Supply (Production), Consumption, Export, Import by Regions

Chapter 6 Global Production, Revenue (Value), Price Trend by Type

Chapter 7 Global Market Analysis by Application

Chapter 8 Manufacturing Cost Analysis

Chapter 9 Industrial Chain, Sourcing Strategy and Downstream Buyers

Chapter 10 Marketing Strategy Analysis, Distributors/Traders

Chapter 11 Market Effect Factors Analysis

Chapter 12 Anti-TSG6 Antibody Global Market Forecast

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‘Jurassic World’ scientists still haven’t learned that just because you can doesn’t mean you should – real-world genetic engineers can learn from the cautionary tale

(THE CONVERSATION) “Jurassic World: Dominion” is hyperbolic Hollywood entertainment at its best, with an action-packed storyline that refuses to let reality get in the way of a good story. Yet, just like its predecessors, it offers an underlying cautionary tale of technological hubris that is very real.

As I explain in my book “Films from the Future,” Stephen Spielberg’s “Jurassic Park,” based on Michael Crichton’s 1990 novel, didn’t shy away from tackling the dangers of unfettered entrepreneurship. and irresponsible innovation. Scientists at the time were closing in on the ability to manipulate DNA in the real world, and the book and film captured emerging concerns that playing God with nature’s genetic code could have devastating consequences. This was captured by one of the film’s protagonists, Dr Ian Malcolm, played by Jeff Goldblum, when he said, “Your scientists were so concerned about whether they could, they didn’t stop to think if they had to.”

In the latest iteration of the “Jurassic Park” franchise, the company comes to terms with the consequences of ill-conceived innovations at best. A litany of “could” over “should” has led to a future in which resurrected and redesigned dinosaurs roam free, and humanity’s dominance as a species is threatened.

At the heart of these films are questions that are more relevant than ever: have the researchers learned the lesson of “Jurassic Park” and sufficiently bridged the gap between “could” and “should”? Or will the science and technology of DNA manipulation continue to outpace any consensus on how to use them ethically and responsibly?

(Re)designing the genome

The first draft of the human genome was released to much fanfare in 2001, paving the way for scientists to read, redesign and even rewrite complex genetic sequences.

However, existing technologies were time-consuming and expensive, putting genetic manipulation beyond the reach of many researchers. The first draft of the human genome cost around US$300 million, and subsequent whole-genome sequences just under $100 million – a prohibitive amount for all but the best-funded research groups. As existing technologies were refined and new ones came online, small labs – and even students and “bio DIY” enthusiasts – could more freely experiment with reading and writing the genetic code. .

In 2005, bioengineer Drew Endy proposed that it is possible to work with DNA the same way engineers work with electronic components. Just as electronics designers are less concerned with the physics of semiconductors than with the components that depend on them, Endy argued that it should be possible to create standardized DNA-based parts called “biobricks” that scientists could use without needing to be experts. in their underlying biology.

The work of Endy and others was the foundation of the emerging field of synthetic biology, which applies engineering and design principles to genetic manipulation.

Scientists, engineers, and even artists have begun to view DNA as biological code that can be digitized, manipulated, and reimagined in cyberspace much like digital photos or videos. This in turn opened the door to the reprogramming of plants, microorganisms and fungi to produce pharmaceutical drugs and other useful substances. Modified yeast, for example, produces the meaty taste of veggie Impossible Burgers.

Despite the growing interest in gene editing, the greatest impediment to the imagination and vision of early synthetic biology pioneers was always the speed and cost of editing technologies.

Then CRISPR changed everything.

The CRISPR revolution

In 2020, scientists Jennifer Doudna and Emanuelle Charpentier won the Nobel Prize in Chemistry for their work on a revolutionary new gene-editing technology that allows researchers to precisely cut out and replace DNA sequences in genes: CRISPR.

CRISPR was fast, cheap and relatively easy to use. And it freed the imagination of DNA coders.

More than any previous advance in genetic engineering, CRISPR has made it possible to apply techniques from digital coding and systems engineering to biology. This cross-fertilization of ideas and methods has led to breakthroughs ranging from using DNA to store computer data to creating 3D “DNA origami” structures.

CRISPR has also paved the way for scientists to explore redesigning entire species, including bringing animals back from extinction.

Gene drives use CRISPR to insert a piece of genetic code directly into an organism’s genome and ensure that specific traits are inherited by all subsequent generations. Scientists are currently experimenting with this technology to control disease-carrying mosquitoes.

Despite the potential benefits of the technology, gene drives raise serious ethical questions. Even when applied to clear public health threats like mosquitoes, these questions are not easy to navigate. They become even more complex when considering hypothetical applications in people, such as increasing athletic performance in future generations.

Gain of function

Advances in gene editing have also made it easier to genetically modify the behavior of individual cells. It’s at the heart of biofabrication technologies that re-engineer simple organisms to produce useful substances ranging from aviation fuel to food additives.

It is also at the center of controversies surrounding genetically modified viruses.

Since the start of the pandemic, there have been rumors that the virus that causes COVID-19 is the result of genetic experiments gone wrong. Although these rumors remain unsubstantiated, they have renewed debate about the ethics of gain-of-function research.

Gain-of-function research uses DNA editing techniques to alter how organisms function, including increasing the ability of viruses to cause disease. Scientists do this to predict and prepare for potential mutations in existing viruses that increase their ability to cause harm. However, such research also raises the possibility of dangerously enhanced virus being released outside the laboratory, either accidentally or intentionally.

At the same time, scientists’ growing mastery of biological source code is what allowed them to rapidly develop the Pfizer-BioNTech and Moderna mRNA vaccines to fight COVID-19. By precisely engineering the genetic code that instructs cells to produce harmless versions of viral proteins, vaccines are able to prime the immune system to react when it encounters the actual virus.

Responsible handling of biological source code

Premonitory as Michael Crichton was, it is unlikely that he could have imagined how much scientists’ abilities to design biology have advanced over the past three decades. Bringing back extinct species, while an active area of ​​research, remains fiendishly difficult. However, in many ways, our technologies are significantly more advanced than those of “Jurassic Park” and subsequent films.

But what have we done on the accountability front?

Fortunately, consideration of the social and ethical aspect of gene editing has gone hand in hand with the development of science. In 1975, scientists agreed on approaches to ensure that emerging recombinant DNA research would be carried out safely. From the outset, the ethical, legal and social dimensions of science have been integrated into the human genome project. Bio-DIY communities have been at the forefront of research into safe and responsible gene editing. And social responsibility is an integral part of synthetic biology competitions.

Yet, as gene editing becomes more powerful and accessible, a community of well-meaning scientists and engineers probably won’t be enough. While the “Jurassic Park” movies take dramatic license in their depiction of the future, they get one thing right: Even with good intentions, bad things happen when you mix powerful technology with scientists who don’t have a clue. not been trained to think about the consequences. of their actions – and didn’t think to ask the experts who did.

Perhaps that’s the abiding message of “Jurassic World: Dominion” – that despite incredible advances in genetic design and engineering, things can and will go wrong if we don’t embrace development and use of technology in a socially responsible manner.

The good news is that we still have time to bridge the gap between “could” and “should” in the way scientists redesign and rearrange the genetic code. But as “Jurassic World: Dominion” reminds moviegoers, the future is often closer than it seems.

Cybin Moves Forward with Phase 1/2a Clinical Trial for Treatment of Major Depressive Disorder

Cybin Inc. CYBNthe biopharmaceutical company “focused on advancing psychedelics into therapeutics” by creating safe and effective therapies for patients to treat a variety of mental health disorders, has received Institutional Review Board approval to launch the first Phase 1/2a clinical trial assess CYB003 for the treatment of major depressive disorder.

An Institutional Review Board, a group constituted under FDA regulations, is appointed to review and oversee biomedical research involving human subjects, with the goal of protecting their rights and welfare. The board has the authority to approve, require modifications (for potential approval), or disapprove research, in accordance with FDA guidelines.

On their behalf, the company’s goal is to launch the study in mid-2022. Through Cybin IRL Limiteda wholly owned subsidiary of Cybin, the company has hired Clinilabs drug development companya contract research organization specializing in central nervous system drug development, to complete the Phase 1/2a clinical trial of CYB003.

The psychedelic tested

As its creators explained, CYB003 is a deuterated compound derived from psilocybin, which is part of a family of molecules called indoleamines which include other neurotransmitters such as serotonin. Psilocybin is dephosphorylated to form its metabolite, psilocin, which can cross the blood-brain barrier.

Given its structural similarity to serotonin, psilocin can easily activate the serotonin 5-HT2A receptor. CYB003 was designed “to achieve less variability in plasma levels, faster onset of action, shorter duration of effect, and potentially better tolerability for a better overall patient outcome,” the company said. . According to Cybin, this psilocybin analog has the potential to effectively treat not only major depressive disorder, but alcohol use disorder as well.

Photo courtesy of Josh Riemer on Unsplash.

Research Associate, Academic Unit of Clinical and Health Sciences (ARAS) with UNIVERSITY OF SOUTH AUSTRALIA

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  • Based at UniSA Clinical & Health Sciences on the City West campus
  • Two full-time fixed-term contracts until December 22, 2023
  • Starting salary: $90,451 per year (plus 17% superannuation)

About the role

Reporting directly to the Lloyd Sansom Chair in Biomaterials Engineering and Nanomedicine, as a Research Associate, you will contribute to the research efforts of the Academic Clinical and Health Sciences Unit and be responsible for academic and industrial research in the proteomics and mass spectrometry group.

This project is funded by a grant from the South African government to support the expansion of services from the Bioplatforms Australia facility funded by the National Collaborative Research Infrastructure Strategy (NCRIS) program.

About UNISA

The University of South Australia is Australia’s corporate university. Our culture of innovation is anchored around global and national connections with academic, research and industrial partners. Our graduates are the new urban professionals, global citizens comfortable with the world and ready to create and respond to change. Our research is inventive and adventurous, and we create new knowledge that is essential to global economic and social prosperity.

About UniSA Clinical and Health Sciences

At UniSA Clinical and Health Sciences, we meet society’s most critical and emerging health needs through quality teaching, learning and research. One of seven academic units, UniSA Clinical and Health Sciences offers a wide range of degrees and conducts world-class research in nursing, midwifery, pharmacy, pharmaceutical sciences, medical sciences, of Laboratory Medicine and Food and Nutrition Sciences with a strong focus on creating positive health outcomes for communities.

UniSA’s headquarters is the center for quality medicine and pharmacy utilization research and with key research concentrations in the areas of mental health and suicide prevention, workforce development, nursing and midwifery, drug discovery, pharmaceutical innovation, health and disease biology and food nutrition and health. , we continue to meet community health needs and contribute to a healthier society.

Core Responsibilities

  • Actively engage with researchers and industry partners internationally, nationally and across the University to contribute to new research directions and outcomes
  • Move projects forward by applying project management, supervision and reporting skills to ensure project success
  • Experience in analyzing complex proteomes via tryptic peptides by MALDI TOF and LC-ESI mass spectrometry
  • Supervise, train and support postgraduate students, internship students and visiting students
  • Prepare publications in peer-reviewed journals, conference and seminar papers arising from research

Essential skills and experience

  • PhD in biochemistry, chemistry and/or analytical chemistry, mass spectrometry or related field.
  • Demonstrated laboratory experience in separation sciences, protein biochemistry, metabolomics, proteomics or environmental analysis
  • Registry of peer-reviewed publications and conference presentations based on opportunity
  • Demonstrated project management skills, including the ability to initiate, plan and manage projects ensuring milestones are met
  • Proven ability to work collaboratively within a research team with staff, students and external providers from diverse backgrounds

Advantages

Getting a great job working with the best is just the start. UniSA rewards its staff with a wide variety of benefits such as:

  • Access to great personal development opportunities
  • Generous 17% pension contributions
  • Flexible working conditions
  • Employee assistance and development programs
  • A range of salary conditioning options, including vehicle hire, laptops and parking fees
  • Varied holidays

Culture

As a university of business, we offer a dynamic and agile work culture that rises to challenges and thrives by forging new paths. Our people are creative and innovative thinkers, communicating with clarity, conviction and enthusiasm. We embrace diversity and inclusion in a dynamic and engaging environment. Our people are authentic, resilient and influential, and we deliver results.

How to register

For a copy of the job description and to apply, please visit Work at UniSA. The online application form lists the specific selection criteria you must meet. Only applications submitted via the Working at UniSA portal will be accepted.

Please send your cover letter to Sara Heidrich, recruitment consultant. For further information about the position or the recruitment process, please contact UniSA Recruitment Central on +61 8 8302 1700 or email recruitment@unisa.edu.au using the job reference number. 4183.

Closing of applications: 11:30 p.m. Monday July 18, 2022

How to register:

Applications must be submitted online, please note that UniSA does not accept applications by email.

  • Start your application by clicking on the ‘BEGIN’ button
  • If you have already created an account, please log in before starting your application
  • If you forgot your login information, click here to reset your password
  • Overview of the application form

UniSA is committed to developing a diverse workforce and a constructive corporate culture in which everyone can thrive.

For further assistance contact Recruitment Central on +61 8 8302 1700 or email recruitment@unisa.edu.au and you will receive a response within one working day.

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Nirvana Life Sciences Announces Patent Filing

Study launched following recent successful pilot study and patent filing

Awakn Life Sciences Corp. (NEO: AWKN) (OTCQB: AWKNF) (FSE: 954) (“Awakn”), a biotechnology company that researches, develops and commercializes therapeutic products to treat addiction with a short-term focus on addiction-related disorders to Alcohol Use (AUD), today announced that they have initiated a larger behavioral addiction study of ketamine as a treatment for gambling disorder. Awakn announced on May 19, 2022 that the company had completed successful pilot study on a range of behavioral addictions. On May 26, 2022, Awakn announced the filing of a Patent Cooperation Treaty (PCT) for the treatment of behavioral addictions with ketamine and ketamine-assisted psychotherapy.

The larger study announced today will include 42 patients with gaming disorder and will see participants undergo a memory reactivation procedure, designed to weaken the link between reward and addiction memories. The largest placebo-controlled study will be the first worldwide investigation to explore this technique for treating gambling disorder.

The study will use advanced EEG (electroencephalography) brain imaging technology and index synaptic plasticity after ketamine administration with the aim of identifying the window of greatest neuroplastic change. This would potentially allow Awakn to predict when therapy will be most effective due to neuroplasticity. The study will also collect detailed pharmacokinetic (PK) data and analyze metabolites as well as review neurological biomarkers.

Awakn CEO Anthony Tennyson commented, “Awakn is dedicated to helping those suffering from addiction, and we are very excited about the significant research and development milestones we have achieved in recent weeks. None of this would be possible without Awakn’s dedication. team and I would like to formally thank them and everyone involved, including patients, doctors and caregivers.”

Gaming disorder affects up to 450 million people[1] people globally. In the United States alone, it is estimated that more than 2.5% of the population suffers from gambling disorders, or more than 8 million people.2. In the absence of pharmacological treatments currently available, the need to find an effective treatment has never been more acute.

About Awakn Life Sciences Corp.

Awakn Life Sciences is a biotechnology company that researches, develops and commercializes combination therapies to treat addiction, with a focus on alcohol use disorders. The Awakn team is made up of renowned research experts, world-renowned chemists, scientists, psychiatrists and psychologists. Drug addiction is one of the greatest unmet medical needs of our time, affecting over 20% of the world’s population and is an industry valued at over $100 billion a year. Awakn is working to disrupt this underperforming industry by advancing the next generation of drugs and therapies for use in combination, through preclinical research and clinical trials.

www.awaknlifesciences.com | Twitter | LinkedIn | Facebook

Notice Regarding Forward-Looking Information

This press release contains certain forward-looking information and forward-looking statements, as defined in applicable securities laws (collectively referred to herein as “forward-looking statements”). Forward-looking statements reflect current expectations or beliefs regarding future events or the future performance of the Company. All statements other than statements of historical fact are forward-looking statements. Often, but not always, forward-looking statements can be identified by the use of words such as “plans”, “expects”, “is planned”, “budget”, “expected”, “estimates”, “continues “, “expects”, “plans”, “predicts”, “intends”, “anticipates”, “targets” or “believes”, or variations of, or the negatives of, such words and expressions or state that certain actions, events or results “may”, “could”, “should”, “should”, “could” or “will” be taken, occur or be carried out, including statements relating to the activities of the Company All forward-looking statements, including those contained herein, are qualified by this cautionary statement.

Although the Company believes that the expectations expressed in these statements are based on reasonable assumptions, these statements are not guarantees of future performance and actual results or developments may differ materially from those indicated in the statements. Certain factors could cause actual results to differ materially from those indicated in the forward-looking information. These include, but are not limited to: COVID-19; fluctuations in general macroeconomic conditions; the Company’s business plans and strategies; the Company’s ability to comply with all applicable governmental regulations in a highly regulated business; the risks inherent in investing in target companies or projects that have limited or no operating history and that are engaged in activities currently considered illegal in certain jurisdictions; changes in laws; limited operating history; dependence on management; additional funding requirements; competition; fluctuations in the securities markets; inconsistent public opinion and perception regarding the medical use of psychedelic drugs; expectations regarding the size of the drug addiction market; and regulatory or policy change. Readers are cautioned that the foregoing list of factors is not exhaustive of factors that could affect forward-looking statements. Accordingly, readers should not place undue reliance on forward-looking statements. The forward-looking statements contained in this press release speak only as of the date of this press release or as of the date or dates specified in such statements.

Investors are cautioned that such statements are not guarantees of future performance and that actual results or developments may differ materially from those projected in the forward-looking information. For further information on the Company, investors are encouraged to consult the Company’s public filings on SEDAR at www.sedar.com. The Company disclaims any intention or obligation to update or revise any forward-looking information, whether as a result of new information, future events or otherwise, except as required by law.

This press release does not constitute an offer to sell or a solicitation of an offer to buy securities in the United States. The securities of the Company and Awakn have not been and will not be registered under the United States Securities Act of 1933, as amended (the “U.S. Securities Law“) or any state securities law and may not be offered or sold in the United States or to United States persons unless registered under United States securities law and applicable state securities laws securities or an exemption from such registration.

Investor requests:
Anthony Tennyson, CEO, Awakn Life Sciences
anthony.tennyson@awaknlifesciences.com

Media inquiries:
America and Canada: KCSA Strategic Communications
Anne Donohe
Adonohoe@KCSA.com

Rest of the world: ROAD Communications
Paul Jarman/Nora Popova
Awakn@roadcommunications.co.uk

1: Problem gambling around the world: an update and systematic review of empirical research (2000-2015):
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5370365
2: Help from the North American Foundation for Gambling Addiction:
https://nafgah.org/statistics-gambling-addiction-2016/

A strange carnivorous dinosaur joins “Rogues’ G”

image: Reconstruction of the ecosystem of the Bahariya oasis in the Sahara desert in Egypt around 98 million years ago, showing the diversity of large theropods (predatory dinosaurs). The newly discovered and as yet unnamed abelisaurid (right) confronts Spinosaurus (center left, with fish in its jaws) and Carcharodontosaurus (center right). In the background, a herd of the sauropod (giant long-necked herbivorous dinosaur) Paralititan (left) gazes warily at these predators, while a herd of an as yet unnamed pterosaur (flying reptile) hovers above.
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Credit: Andrew McAfee, Carnegie Museum of Natural History.

ATHENS, Ohio (June 8, 2022) – A team of Egyptian-American researchers has announced the discovery of a new type of large carnivorous dinosaur, or theropod, from a famous fossil site in Egypt’s Sahara Desert. The fossil of a yet unnamed species provides the earliest known record of the abelisaurid theropod group from a mid-Cretaceous (~98 million years old) rock unit known as the Bahariya Formation, which is exposed in the West Bahariya oasis. Desert of Egypt.

At the beginning of the 20e century, this locality provided the original specimens of a host of remarkable dinosaurs, including the colossal sail-backed fish-eater Spinosaurus– which were later destroyed during World War II. Abelisaurid fossils had previously been found in Europe and many continents of today’s Southern Hemisphere, but never before in the Bahariya Formation. The team describes the discovery of the Bahariya abelisaurids in a article published today in Royal Society Open Science.

The study was led by Ohio University graduate student Belal Salem, based on work he initiated while a member of Mansoura University’s Vertebrate Paleontology Center ( MUVP) in Mansoura, Egypt. The research team also included Patrick O’Connor, professor of biomedical sciences at Ohio University’s Heritage College of Osteopathic Medicine; Matt Lamanna, associate curator of vertebrate paleontology at the Carnegie Museum of Natural History; Sanaa El-Sayed, doctoral student at the University of Michigan and former vice-director of MUVP; Hesham Sallam, professor at the American University in Cairo (AUC) and Mansoura University and founding director of MUVP; and other colleagues from Benha University and the Egyptian Environmental Affairs Agency.

The fossil in question, a well-preserved vertebra from the base of the neck, was recovered by an MUVP expedition in 2016 from Bahariya Oasis. The vertebra belongs to an abelisaurid, a kind of bulldog-headed, small-toothed, small-armed theropod that is estimated to have been about six meters (20 feet) in length. Abelisaurids – notably represented by the horned and demonic-looking Patagonian form Carnotaurus of jurassic world and prehistoric planet fame – were among the most diverse and geographically widespread large predatory dinosaurs in the southern landmasses during the Cretaceous Period, the last period of the Age of Dinosaurs. In the same way Spinosaurus and two other giant theropods (Carcharodontosaurus and Bahariasaurus), the new abelisaurid fossil adds another species to the group of large predatory dinosaurs that roamed what is now the Egyptian Sahara around 98 million years ago.

“During the mid-Cretaceous, the Bahariya Oasis would have been one of the most terrifying places on earth,” says Salem, a new student in Ohio University’s biological sciences graduate program. “How all these huge predators managed to co-exist remains a mystery, although it’s probably related to the fact that they ate different things, that they adapted to hunt different prey.”

The new vertebra has implications for the biodiversity of Cretaceous dinosaurs in Egypt and throughout the northern region of Africa. It is the oldest known Abelisauridae fossil from northeast Africa, and shows that by the mid-Cretaceous these carnivorous dinosaurs ranged over much of the northern part of the continent from east to west, from present-day Egypt to Morocco, to the south. such as Niger and potentially beyond. Spinosaurus and Carcharodontosaurus are also known from Niger and Morocco, and a close relative of Bahariasaurus was also found in the latter nation, suggesting that this large to gigantic theropod fauna co-existed across much of North Africa at this time.

How can the discovery of a single cervical vertebra lead researchers to conclude that the fossil belongs to a member of the Abelisauridae, a kind of carnivorous dinosaur that has never been found in the Bahariya Formation before? The answer is remarkably simple: it is virtually identical to the same bone in other better known abelisaurids such as Carnotaurus from Argentina and Majungasaurus from Madagascar. As co-author and Salem graduate advisor Patrick O’Connor, who in 2007 published a comprehensive study of the spinal anatomy of Majungasaurus, explains: “I have examined abelisaur skeletons from Patagonia to Madagascar. My first glimpse of this specimen from photos left no doubt as to its identity. The neck bones of abelisaurids are so distinctive.

The website

Bahariya Oasis is renowned in paleontological circles for providing the type specimens (the original fossils, first discovered and named after them) of several extraordinary dinosaurs in the early 20e century, including, the most famous, Spinosaurus. Unfortunately, all of the Bahariya dinosaur fossils collected before World War II were destroyed in an Allied bombing of Munich in 1944.

As a graduate student in the early 2000s, study co-author Matt Lamanna helped make the first dinosaur discoveries in the oasis since the infamous 1944 air raid, including the gargantuan sauropod ( long-necked herbivorous dinosaur) paralititan. “Bahariya Oasis has achieved near-legendary status among paleontologists for producing the earliest known fossils of some of the world’s most amazing dinosaurs,” says Lamanna, “but for more than three-quarters of a century these fossils have not only exist as pictures in old books. Fortunately, discoveries made during recent expeditions led by AUC and MUVP researchers, such as the new abelisaurid vertebra, are helping to restore the paleontological legacy of this classic site. These expeditions have recovered a slew of additional fossils that the researchers plan to uncover in the near future.

As team member Sanaa El-Sayed, who co-led the 2016 expedition that collected the abelisaurid vertebra, explains, “This bone is just the first of many important new dinosaur fossils from the ‘Bahariya oasis’.

The Bahariya Formation promises to shed light on Africa’s mid-Cretaceous dinosaurs and the extinct ecosystems they once lived in. Unlike more explored rocks of the same age in Morocco which tend to produce isolated bones, the Bahariya Formation appears to preserve partial skeletons of dinosaurs and other land animals with relatively high frequency. The more bones preserved in the skeleton of a given skeletal fossil species, the more paleontologists can generally learn about it. The propensity of Bahariya Oasis to produce associated partial skeletons suggests that much remains to be learned from this historical locality.

“When it comes to Egyptian dinosaurs, we’ve only scratched the surface,” notes study co-author Hesham Sallam. “Who knows what else might be out there?” Recent efforts by Professor Sallam and his collaborators around the world are placing Egyptian students in leading roles in the research process. The field expedition that recovered the new abelisaurid fossil and follow-up laboratory work were led by MUVP-based student researchers and contributing authors to the paper. “Working with MUVP, its faculty and students, like Belal Salem, continues to inspire me, as I see the next generation of paleontologists playing a leading role in sharing their insights into the history of our planet,” adds O’Connor.

Research on the new abelisaurid vertebra was supported by a field research grant to Matt Lamanna of the National Geographic Society’s Committee for Research and Exploration, grants to Hesham Sallam of Mansoura University, and the intramural grants from the American University in Cairo, and a grant to Patrick O’ Connor from the National Science Foundation (EAR-1525915).


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Julian Gonzales Named CoSIDA Academic All-American

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LAKE CHARLES – Outfielder McNeese Julien Gonzales was a CoSIDA Academic All-American, the organization announced Wednesday.

The Sulfur eldest, who earned third-team honors and becomes the seventh Cowboy in school history to win the award, compiled a 3.95 GPA while majoring in pre-medical biology and in chemistry and psychology. He was entered into the All-America ballot after earning first-team all-district academy honors in May.

On the field in the 2022 season, Gonzales started in all 57 games and hit .280 with nine home runs and 44 RBIs, which tied him for first on the team as he helped lead the Cowboys. to the Southland Conference regular season championship for the first. time since 2017.

He ranked second on the team with 16 doubles, 52 runs scored and three triples while his 22 stolen bases ranked him third on the team.

Gonzales is the only Southland Conference player to be elected as an Academic All-American.

2021-22 Academic All-America ®
baseball team
NCAA Division I

FIRST TEAM
pos. Name School GPA Year Principal

P Thomas Harrington Campbell University 3.81 So. Pre-Physical Therapy Track in Kinesiology
P Alex Williams Stanford University 3.42 Sr. Management Science & Engineering
C Kyle Gurney Bowling Green 3.96 Jr. Business Analytics and Intelligence
C Evan Russell University of Tennessee 3.42/4.00 Gr. Finance (U) / Ag. Leadership, Education and Communication (G)
IF Jake Gelof University of Virginia 3.71 So. media studies
IF Jace Jung (1) Texas Tech University 3.72 So. sports management
IF Jake McCaw Illinois State University 3.92/4.00 Gr. Business Information Systems (U) / MBA (G)
IF Jack Smith Washington State University 4.00/4.00 Gr. MBA (G)
IF RJ Yeager (3) Mississippi State University 4.00/4.00 Gr. Workforce Education Branch
DE Aaron Anderson (1) Liberty University 4.00/4.00 Gr. MBA
DE Griffin Merritt University of Cincinnati 3.90 Sr. Biological Sciences
OF Tanner O’Tremba University of Arizona 4.00 Psychology Sr.
DH Mike Steffan Canisius College 3.98/3.88 Gr. Finance

SECOND TEAM
pos. Name School GPA Year Principal
P John Michael Bertrand University of Notre Dame 3.43/3.30 Gr. Marketing Strategy
P Jonathan Fincher (3) Louisiana Tech University 3.90 Gr. Biology (U) / Kinesiology & Health Sciences (G)
IF Andrew Jenkins Georgia Tech 3.79 Jr. Business Administration
IF Luc Lipcius University of Tennessee 3.34/3.96 Gr. Aerospace Engineering (U) / MBA and Engineering (G)
IF Kemuel Thomas-Rivera Tarleton State University 4.00/4.00 Gr. Kinesiology
OF Brock Jones (2) Stanford University 3.59 Jr. Science, Technology and Society
DE Steele Netterville (1) Louisiana Tech University 3.93 Gr. Biology (U) / Kinesiology & Health Sciences (G)
DE Jake Thompson Oklahoma State University 3.72/4.00 Gr. Academic/Business Studies (U)/Leisure Studies (G)
DH Jacob McKeon Washington State University 3.98 Jr. Kinesiology

THIRD TEAM
pos. Name School GPA Year Principal

P John Bakke Morehead State University 4.00/4.00 Gr. Wellness Promotion
P Jackson Smeltz Purdue University 3.70 Senior Agribusiness
C Matt Wood Pennsylvania State University 3.80 Jr. Supply Chain Management and Information Systems
IF Matt Coutney Old Dominion University 3.40 Sr. Leadership & Business
IF Ryan Galanie Wofford College 3.79 Jr. IT/Spanish
IF Daniel Harris IV University of Kentucky 3.80/4.00 Gr. Sport, Fitness and Recreation Management
IF Reid Homan University of North Alabama 4.00/4.00 Gr. MBA – Information Systems (G)
DE Brian Ellis Florida Gulf Coast University 3.79/4.00 Gr. Exercise Science (U)/Health Services Administration. (G)
OF Julien Gonzales McNeese State University 3.95 Sr. Biology

DE Braydon Webb University of Arkansas 4.00/4.00 Gr. Operations Management
DH Owen Diodati University of Alabama 4.00 Jr. Finance

CoSIDA Academic All-America® Team Member of the Year: Aaron Anderson, Liberty University

(1) – 1st All-America® Academic Team in 2020-21
(2) – 2nd Academic All-America® team in 2020-21
(3) – 3rd Academic All-America® team in 2020-21

Matthew McConaughey delivers powerful White House speech on Uvalde

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It shouldn’t take a celebrity to make us all sit up and pay attention, but Matthew McConaughey’s powerful White House speech on Tuesday did just that.

McConaughey, a native of Uvalde, was in Washington, DC to call on lawmakers to address gun control. During his speech in the White House briefing room, he also praised several of the victims who died in the shooting at Robb Elementary on May 24.

He shared that one of the victims, Maite Rodriguez, 10, dreamed of becoming a marine biologist when she grew up loving animals and the environment. She often wore a pair of high-top green Converse sneakers — her favorite color — with a heart she drew in marker on the tip of the right shoe.

McConaughey motioned for his wife, Camila Alves McConaughey, to hold Maite’s replica shoes during his speech.

“It was the same green Converse on his feet that turned out to be the only clear evidence that could identify him after the shooting,” he said.

He then slammed the podium in anger while getting emotional. McConaughey said the bodies of the 19 children and two teachers who were killed were “mauled” by exit wounds from the AR-15 rifle used to shoot them. It was reported that in many cases DNA testing was required to identify the victims as they were largely unrecognizable.

“A lot of kids were left not just dead but hollow,” McConaughey lamented.

It’s a terrifying reality, but one we must face nonetheless.

Related: Uvalde teacher shot and injured says he’ll ‘never forgive’ police for inaction

The actor and his family returned to his hometown of Uvalde following the shooting to meet with the victims’ families, coroners and funeral directors. He said each of those grieving families told him they didn’t want their loved ones to die in vain and they didn’t want other families to go through what they are now going through again.

“The common thread — regardless of anger, confusion and sadness — was the same,” he said. “How can these families continue to honor these dead by keeping the dreams of these children and teachers alive? Again, how does the loss of these lives matter? »

He called out politicians on “both sides” for failing to take action on gun control. He called for universal background checks and raising the purchase age for assault rifles from 18 to 21 while implementing a national waiting period for assault rifles as well.

“Can both sides see past the ongoing political issue and admit that we have a life preservation issue on our hands?” he asked. “We need to soberly, humbly and honestly look at ourselves in the mirror and rename ourselves based on what we truly value.”

Related: Girl Scouts Pays Tribute to Uvalde Victim Amerie Jo Garza in the Most Beautiful Way

He urged those in power to realize that “responsible gun owners are tired of the Second Amendment being abused and misused by deranged individuals.”

“These regulations are not a step backwards,” he said. “It’s a step forward for civil society.”

Maite Rodriguez was buried on May 31. Her loving obituary described her as a girl with a “caring heart” and an honor student who loved learning about animals and the ocean. Texas A&M University-Corpus Christi, the college Maite dreamed of attending to become a marine biologist, is now offering a scholarship in her name.

“Maite was a sweet girl and those who knew and loved her were blessed with her kind, ambitious, friendly and gentle soul.”

uvalde

McConaughey gives an impassioned speech on gun reform at the White House

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WASHINGTON — Actor and Uvalde native Matthew McConaughey demanded that lawmakers overcome political differences and pass gun reform measures in a powerful and impassioned speech during Tuesday’s White House press briefing.

“This shouldn’t be a partisan issue…but the people in power haven’t acted,” McConaughey said. “Can both sides rise above? Can both sides see beyond of the current political problem and admit that we have a life preservation problem on our hands?

McConaughey and his wife, Camila, have spent much of the past week in his hometown meeting with the families of the 19 children and two teachers who were massacred in the May 24 shooting at Robb Elementary School.

“Children were left not just dead, but empty”

Having gained access to the White House press room podium after meeting President Joe Biden, an emotional McConaughey spoke for more than 20 minutes, at times choking back tears and slamming his hand on the lectern while sharing heartbreaking details on some of the victims.

He spoke of 10-year-old Alithia Ramirez’s passion for art while holding one of her drawings, and shared 9-year-old Maite Rodriguez’s dream of one day being a marine biologist.

After her death, Rodriguez’s body was identifiable only by her favorite shoes she wore every day — bright green Converses with a heart on her right toe, McConaughey said. Camila held these shoes, showing the room and the cameras as he spoke.

“The children were left not just dead, but hollow,” McConaughey said, describing the horrific injuries inflicted by the shooter’s AR-15 rifle. “How does the loss of these lives matter? As we honor and recognize the victims, we must recognize that this time (it) seems like something is different.

After: Matthew McConaughey: It’s time to act on gun liability

Matthew McConaughey calls for universal background checks and more gun reform measures

This week, McConaughey met with lawmakers from both sides of the aisle to push for meaningful gun reform legislation.

In an opinion piece published in the American-Statesman on Monday, and again at the White House on Tuesday, McConaughey called for universal background checks, raising the minimum age to buy a gun from 18 to 21, and demanding a mandatory waiting period to purchase assault weapons.

He has also backed “red flag” laws, which allow judges to temporarily remove guns from those deemed a danger to themselves and others.

“Responsible gun owners are tired of the Second Amendment being abused and misused by deranged individuals,” said McConaughey, a gun owner himself. “These regulations are not a step backwards. This is a step forward for civil society.

The U.S. House Committee on Oversight and Reform is scheduled to hold a hearing Wednesday morning on gun violence in which they will hear from several witnesses, including a fourth-grade student who survived the Uvalde shooting and two parents of one from Texas victims.

Sen. Chris Murphy, a Connecticut Democrat, is leading negotiations with Senate Republicans on gun reform measures.

According to White House press secretary Karine Jean-Pierre, Biden is optimistic about making progress.

“We haven’t seen this type of negotiations or this type of rapprochement on the two sides for a very long time. It’s been decades. He is therefore encouraged,” said Jean-Pierre, adding that the president is ready to approve the reforms that cross the narrowly divided Senate, even if they do not include all of his objectives.

“He thinks every step is a step forward,” Jean-Pierre said.

Edison High School Class of 2022 has a record 115 valedictorians

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Edison High School’s commencement ceremony Monday afternoon (June 6) at the Save Mart Center.

mortizbriones@vidaenelvalle.com

Edison High School’s class of 2022 sat proudly in the middle of the Save Mart Center on Monday afternoon (June 6) ready for its commencement ceremony with an incredible and record-breaking 115 valedictorians.

“Blood, sweat, tears, hours of procrastination on the ticking clock and sleeping with their cameras off paved the way for this moment,” said speaker Braylen Gonzales, who graduated from valedictorian with distinction.

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Edison High School class speaker Braylen Gonzáles, who graduated valedictorian with honors, during the commencement ceremony Monday afternoon (June 6) at the Save Mart Center. Maria G. Ortiz-Briones mortizbriones@vidaenelvalle.com

“Today we are here at one of the happiest times of our lives. wondering what’s next? There’s no card, no 13th grade. Our lives have already begun,” said said Gonzales “The COVID-19 pandemic will go down in history as one of the most notable events in the world and we, the Class of 2022, are living through history.”

While in some form the pandemic had caused so much loss to each of them, Gonzáles said, “We gained something precious. Through these difficulties, we learn that anything is possible and with these limitless possibilities, pursuing our dreams and aspirations is effortless.

For instance, summa cum laude valedictorians Alina Alonzo will attend Fresno State where she will major in political science while Leslie Arredondo will go to the Campuswide Honors Collegium Program at UC Irvine and Julio Castillo will attend UC Berkeley, majoring in economics and minoring in philosophy .

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Summa Cum Laude valedictorians Alina Alonzo will attend California State University, Fresno, where she will major in political science, while Leslie Arredondo will attend the Campuswide Honors Collegium program at the University of California, Irvine María G. Ortiz-Briones. mortizbriones@vidaenelvalle.com

All three earned a 4.32 GPA, the highest possible grade point average.

Arredondo plans to major in biological sciences in hopes of one day becoming a geneticist specializing in forensic genealogy.

Arredondo’s favorite memory in high school was advocating with the superintendents of the Fresno Unified School District and the Central Unified School District for a new policy change.

After graduating from college, Castillo plans to become a financial advisor or anything related to the world of finance.

“We, the Class of 2022, can aspire to be anything. And with that knowledge, we look forward to the better future the world has to offer,” Gonzales said. “Tomorrow, each of us will begin our individual lives creating diversity and identity to show the world who Edison High Class of 2022 is.”

V_GRAD-HS-EDISON_06-06-22_MOB (2).JPG
Edison High School’s commencement ceremony Monday afternoon (June 6) at the Save Mart Center. Maria G. Ortiz-Briones mortizbriones@vidaenelvalle.com

And among those beginning their brighter future is Eduardo García, also valedictorian summa cum laude, who will attend Smithcamp Family Honor College at Fresno State where he will major in biology. García hopes to attend medical school to become an orthopedic surgeon.

Through Edison’s Biomed Pathway, García had the opportunity to explore his medical interest during his four years in high school.

“The real world can sometimes be difficult. But with those challenges come the rewards of growth and prosperity,” Gonzales said, adding that Edison and their families prepared them “for those future obstacles. Today, together, we are like one multi-striped tiger. Now, I don’t know about you guys, but after the ceremony, I definitely feel 22. Thank you.

Edison High School

June 6, 2022

SaveMart Center / Fresno

Latin inscription: 70.1%

Latino Summa Cum Laude winners: Alina Alonzo, Leslie Arredondo, Julio Castillo, Eduardo Garcia, Lily Garcia, Natalya Gonzáles, Kimberly González, Daniel Leal, Vanessa López, Alexsandra Martínez Tinoco, Andrea Navarro Macias Ochoa, Brianna Sotelo, Naylene Velasquez, Karla Zalapa.

V_GRAD-HS-EDISON_06-06-22_MOB (6).JPG
2022 Edison Summa Cum Laude 35 valedictorians – 4.32 highest GPA recognized on stage. Maria G. Ortiz-Briones mortizbriones@vidaenelvalle.com

Underline: This year, Edison High School’s Class of 2022 graduates had an impressive 115 valedictorian majors, including 35 summa cum laude majority — 4.32 GPA — recognized on stage.

Quotation: “Let me be clear, with independence comes responsibility. …. Your future decisions will impact the quality of life for years to come,” said Edison High School Principal José Luis Muñoz.

Diabetes-Friendly Program Produces Significant Effects on Glycemic Control and Body Weight

Study results from three clinical trial sites show that a WW International, Inc. (“WeightWatchers” or “WW”) program tailored for people with diabetes helped participants lose weight, reduce blood sugar and improve their general well-being.

Despite recent advances, there are still gaps in diabetes management for the more than 37 million people with diabetes in the United States, most of whom are also overweight or obese. The results of these trials show that the WW diabetes-friendly program produces favorable improvements in glycemic control, weight, and diabetes-related distress that are both statistically significant and clinically meaningful. »


John W. Apolzan, Ph.D., assistant professor and nutrition scientist, Pennington Biomedical Research Center, and clinical trial principal investigator

The study results were announced today at the 82nd Scientific Session of the American Diabetes Association (ADA).

An estimated 90% of people with diabetes are also overweight or obese, and 30-53% of new cases of diabetes in the United States are obesity-related. Current ADA treatment guidelines recognize the importance of weight management in patients with type 2 diabetes who are also overweight or obese to improve glycemic control.

The six-month, single-arm clinical trial was conducted at three sites (Pennington Biomedical, University of Florida, and Virginia Commonwealth University) and examined the effectiveness of the virtual WeightWatchers program on glycemic control and weight loss in 136 participants with type 2 diabetes who had an average baseline A1c of 7.9. The results demonstrated that the WeightWatchers diabetes-friendly program had clinically significant and statistically significant effects, including:

  • HbA reduction1 C of 0.76. Mean HbA decreases of participants1 C levels at three and six months exceeded the standards set by the FDA for drug therapy (treatment with a drug) approval.
  • Average weight loss of 5.7% and decrease in waist circumference of more than two inches. Modest weight loss of at least five percent of a person’s body weight can contribute to beneficial health effects, including improvements in blood pressure, blood cholesterol, and blood sugar levels.
  • Decreased diabetes-related distress by 9.8%. Participants experienced a reduction in emotional burden, diet-related stress, and overall diabetes-related distress.

“Built on the science-based approach of WeightWatchers, our tailored program helps people with diabetes develop and maintain healthy habits based on their needs and lifestyle,” said Gary Foster, Ph.D. , Scientific Director, WW. “We remain committed to supporting people living with diabetes with scalable solutions and are encouraged by the positive clinical trial results presented at the ADA.”

“Penington Biomedical’s mission includes stemming the epidemics of obesity and diabetes, which can lead to a number of serious health issues, including heart and kidney disease. Finding solutions that help our residents live healthier lives by better managing chronic diseases like type 2 diabetes is one of the research center’s highest priorities,” said Pennington Biomedical Executive Director John Kirwan, PhD.

Participants in the clinical trial followed WeightWatchers’ new diabetes-friendly program.

The study was supported by a grant from WW International, Inc. The information presented does not constitute an endorsement or recommendation by Pennington Biomedical.

Source:

Journal reference:

Apolzan, J.W. et al. (2022) A suitable weight management program for adults with type 2 diabetes: effects on glycemic control. Diabetes. doi.org/10.2337/db22-567-P.

New technology protects the authenticity of engineered cell lines

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Dr. Leonidas Bleris (front) and Dr. Yiorgos Makris, preparing samples in the laboratory, use a laminar flow tissue culture hood, an enclosed cabinet designed to prevent contamination, to work with mammalian cell lines. Bleris and Makris have introduced technology to protect personalized cell lines from misidentification, cross-contamination and illegal replication. Credit: University of Texas at Dallas

Advances in synthetic biology and genome editing have led a growing industry to develop personalized cell lines for medical research. However, these modified cell lines may be vulnerable to misidentification, cross-contamination, and illegal replication.

A team of researchers from the University of Texas at Dallas has developed a first-of-its-kind method to create a unique identifier for each copy of a cell line to allow users to verify its authenticity and protect intellectual property (IP ) from the manufacturer. The engineers demonstrated the method in a study published online May 4 and in the May 6 print edition of Scientists progress.

The patent-pending technology is the result of an interdisciplinary collaboration among faculty members at UT Dallas. The corresponding co-authors of the study are Dr. Leonidas Bleris, professor of bioengineering specializing in genetic engineering, and Dr. Yiorgos Makris, professor of electrical and computer engineering, an expert in electronic equipment security.

Personalized cell lines are used in the development of vaccines and targeted therapies for a range of diseases. The global cell culture market is expected to reach $41.3 billion by 2026, from $22.8 billion in 2021, according to forecasts by market research firm MarketsandMarkets.

UT Dallas engineers’ research to develop unique identifiers for genetically modified cells was inspired by what are known as physically unclonable functions (PUFs) in the electronics industry. A PUF is a physical characteristic that can serve as a unique “fingerprint” for a semiconductor device such as a microprocessor. In semiconductors, PUFs are based on the natural variations that occur during the manufacturing process and must meet three requirements: they must have a unique footprint, produce the same footprint each time they are measured, and be virtually impossible to reproduce.

To apply this concept to engineered cells, the researchers developed a two-step process that takes advantage of a cell’s ability to repair damaged DNA, which is made up of sequences of small molecules called nucleotides.

First, they embedded a five-nucleotide barcode library into a part of the cell’s genome called the safe harbor, where the modification will not harm the cell. However, barcodes alone do not satisfy all three properties of PUFs. In the second step, the researchers used the gene-editing tool CRISPR to cut the DNA close to the barcode. This action forces the cell to repair its DNA using random nucleotides, a process called non-homologous error repair. During this repair process, the cell naturally inserts new nucleotides into the DNA and/or deletes others – collectively these are called indels (insertions/deletions). These random patches, in combination with the barcodes, create a unique pattern of nucleotides that can help distinguish the cell line from any other.

“The combination of barcoding with the inherently stochastic cellular error-repair process results in a unique and non-reproducible fingerprint,” said Bleris, who is also the Cecil H. and Ida Green Professor of Systems Biology Sciences.

This first generation of CRISPR-designed PUFs allows researchers to confirm that cells were produced by a particular company or lab, a process called attestation of provenance. Along with further research, the engineers aim to develop a method to track the age of a specific copy of a cell line.

“Companies developing cell lines are making a huge investment,” Bleris said. “We need a way to tell 1,000 copies of the same product apart. Even if the products are identical, each one has a unique identifier, which cannot be duplicated.”

Makris said the tech cell development business is so new that companies are focusing on monetizing their investments rather than security and provenance attestation. He said the semiconductor industry was the same in the beginning until incidents of counterfeiting and tampering highlighted the need for security measures.

“We think this time maybe we can be ahead of the curve and have that capability developed just as the industry realizes it needs it,” Makris said. “It will be too late when they realize they have been hacked and someone has monetized their IP.”

Other study authors include Dr. Yi Li, a bioengineering research scientist; Mohammad Mahdi Bidmeshki Ph.D., former postdoctoral researcher in the Makris lab; Taek Kang, biomedical engineering doctoral student and Eugene McDermott Graduate Fellow; and Chance M. Nowak, graduate student in biological engineering.


Highly secure physically unclonable cryptographic primitives based on interfacial magnetic anisotropy


More information:
Yi Li et al, Unclonable Genetic Physical Functions in Human Cells, Scientists progress (2022). DOI: 10.1126/sciadv.abm4106

Provided by the University of Texas at Dallas


Quote: New Technology Protects Authenticity of Modified Cell Lines (June 6, 2022) Retrieved June 6, 2022 from https://phys.org/news/2022-06-technology-authenticity-cell-lines.html

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Most of our evolutionary trees could be wrong

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Elephant shrews are more closely related to elephants than shrews, according to molecular evolutionary trees.

An evolutionary tree, or phylogenetic tree, is a branching diagram showing the evolutionary relationships between various biological species based on similarities and differences in their characteristics. Historically, this has been done using their physical characteristics – the similarities and differences in the anatomy of various species.

However, advances in genetic technology now allow biologists to use genetic data to decipher evolutionary relationships. According to a new study, scientists are finding that molecular data lead to vastly different results, sometimes overturning centuries of scientific work in classifying species by physical traits.

New research from scientists at the University of Bath’s Milner Center for Evolution suggests that determining the evolutionary trees of organisms by comparing anatomy rather than gene sequences is misleading. The study, published in the journal Communications Biology May 31, 2022 shows that we often need to overturn centuries of scholarly work that classified living things based on their appearance.

“This means that convergent evolution has fooled us – even the smartest evolutionary biologists and anatomists – for over 100 years!” — Matthew Wills

Since Darwin and his contemporaries in the 19th century, biologists have attempted to piece together the “family trees” of animals by carefully examining differences in their anatomy and structure (morphology).

However, with the development of rapid genetic sequencing techniques, biologists are now able to use genetic (molecular) data to help piece together the evolutionary relationships of species very quickly and inexpensively, often proving that organisms we formerly thought to be intertwined actually belong to completely different organizations. tree branches.

For the first time, Bath scientists compared evolutionary trees based on morphology with those based on molecular data, and mapped them according to their geographic location.

They found that animals grouped by molecular trees lived more closely together geographically than animals grouped using morphological trees.

Matthew Wills, professor of evolutionary paleobiology at the Milner Center for Evolution at the University of Bath, said: “It turns out that we got a lot of our evolutionary trees wrong.

“For over a hundred years we have classified organisms based on their appearance and anatomical assembly, but molecular data often tells us a rather different story.

“Our study statistically proves that if you build an evolutionary tree of animals based on their molecular data, it often matches their geographical distribution much better.

“Where things live – their biogeography – is an important source of evidence for evolution that was familiar to Darwin and his contemporaries.

“For example, the tiny elephant shrews, aardvarks, elephants, golden moles and swimming manatees all descended from the same large branch of mammalian evolution – despite the fact that they look completely different from each other. (and live in very different ways).

“The molecular trees put them all together in a group called Afrotheria, supposedly because they all come from the African continent, so the group fits the biogeography.”

Molecular evolutionary trees Elephant Shrew

Molecular evolutionary trees show that elephant shrews are more closely related to elephants than to shrews. 1 credit

The study found that convergent evolution – when a characteristic evolves separately in two groups of genetically unrelated organisms – is much more common than biologists previously thought.

Professor Wills said: ‘We already have many famous examples of convergent evolution, such as flight evolving separately in birds, bats and insects, or complex camera eyes evolving separately in squid and insects. humans.

“But now, with the molecular data, we can see that convergent evolution is happening all the time – things that we thought were closely related often turn out to be far apart on the tree of life.

“People who make a living as look-alikes aren’t usually tied to the celebrity they impersonate, and individuals within a family don’t always look alike – that’s also the same with evolutionary trees. .

“It proves that evolution keeps reinventing things, coming up with a similar solution each time the problem is encountered in a different branch of the evolutionary tree.

“This means that convergent evolution has fooled us – even the smartest evolutionary biologists and anatomists – for over 100 years!”

Dr Jack Oyston, research associate and first author of the paper, said: “The idea that biogeography can reflect evolutionary history was largely what prompted Darwin to develop his theory of evolution by natural selection, so it’s quite surprising that it hasn’t really been considered directly as a way to test the precision of evolutionary trees in this way before now.

“What’s most exciting is that we’re finding strong statistical evidence that molecular trees fit better not only in groups like Afrotheria, but also in the tree of life in birds, reptiles, insects and plants.

“The fact that it is such a widespread model makes it much more potentially useful as a general test of different evolutionary trees, but it also shows how ubiquitous convergent evolution has been when it comes to acts to mislead us.”

Reference: “Molecular phylogenies map to biogeography better than morphological ones” by Jack W. Oyston, Mark Wilkinson, Marcello Ruta and Matthew A. Wills, May 31, 2022, Communications Biology.
DOI: 10.1038/s42003-022-03482-x

Free Patent Protection Workshop, Lucid Founder Speaks to ACG, Acadian Plans New EMT Program | Economic news

Geological Society of New Orleans hears about LSU campus mounds

The Geological Society of New Orleans will hold a Zoom meeting at 11:30 a.m. Monday.

Brooks B. Ellwood, Professor Emeritus in LSU’s Department of Geology and Geophysics, will discuss recent radiocarbon dating that revealed one of the mounds on the LSU campus is the oldest known, intact man-made structure in North America.

To register for the meeting, go to nogs.org/events.

GBRIA Industrial Show at the Lamar-Dixon Expo Center

The Greater Baton Rouge Industry Alliance will hold its first industry showcase from 2 to 6 p.m. Thursday at the Lamar-Dixon Expo Center in Gonzales.

Participants will be able to find cost-effective solutions, ideas for improving efficiency and the latest technologies available to the industry.

Targeted industries include petrochemicals, energy, paper, oil refining and other South Louisiana manufacturing industries. Plant personnel, industrial support departments, maintenance efficiency personnel, turnaround organizations, environmental support teams, training providers, suppliers and vendors are encouraged to attend.

There will also be continuing education courses covering topics such as ethics, water supply for industrial plants and engineering.

Registration is available at gbria.org/industryshowcase.

Free Workshop on Patent Protection Wednesday

A free workshop on how to seek patent protection will be held Wednesday at 4 p.m.

Mark Melasky, attorney at Intellectual Property Consulting, will moderate the hybrid seminar. The event will take place in person at the offices of IP Consulting, 400 Poydras St., Suite 1400, New Orleans or via Zoom.

The workshop will cover topics such as how to get a patent, what to expect during the patent registration process, patent infringement issues and timelines.

Email gene@ellanola.org to RSVP for a seat or to get the Zoom link.

Lucid Founder to Speak to ACG on Tuesday

Patrick Comer, the founder of Lucid, will address the Association for Corporate Growth at 11:30 a.m. Tuesday as part of his notable speaker series.

Comer sold his market research company for more than $1 billion last year.

Lunch will be at August Restaurant, 301 Tchoupitoulas St., New Orleans. Admission is free for members of the association, $65 for non-members. To register, go to acg.org.

Edison Chouest Offshore Wins Contract to Serve Long Island Wind Farms

Edison Chouest Offshore has been awarded a contract to provide charter services to two offshore wind farms on Long Island.

The hybrid vessel will be based at the South Brooklyn Marine Terminal and will operate partially on battery power. It will be able to accommodate up to 60 wind technicians working on the Empire Wind 1 and Empire Wind 2 developments.

The charter agreement with Empire Offshore Wind, a joint venture between Equinor and BP, is expected to begin in the mid-2020s.

Acadian Launches Latest Accelerated EMT Program

Acadian Ambulance and the National EMS Academy are launching the latest series of crash courses for emergency medical technicians in New Orleans.

The program will select those interested in becoming certified as an emergency medical technician and will pay them while they are trained. If successful, they will then serve as paramedics.

Compared to the traditional EMT program, which takes four months, the accelerated program is a seven-week course. Acceptance into the program is competitive. Acadian will cover the course fees and costs. While studying, students will earn $11 per hour.

The biggest stories in business, delivered every day. Register today.

The last day to apply for the program is June 20 and classes will start on July 11. Classes will be held in the New Orleans area.

To learn more about the program or to apply, visit nationalemsacademy.com/programs/accelerated-emt-program-new-orleans/.

New Orleans Conference for Small Business Owners and Entrepreneurs

The third annual Biz Chiefs Business Conference will be held June 24-26 at the Saint Vincent Hotel, 1507 Magazine St., New Orleans.

The event aims to build and grow profitable businesses and will include sessions covering Intellectual Property/Trademarks, Equities, Business Credit, Financial Strategies, E-Commerce and Marketing. Speakers include Lakeisha Robichaux, Founder and CEO, Chief of Minds; Lori B. Jackson, director of the Urban League of Louisiana’s Women’s Business Resource Center; and Anthony Kimble, founder and managing partner of Kimble Properties, a real estate investment and development firm.

Registration is $249 for general admission and $899 for a VIP package, which includes a business counseling session after the conference. For more information or to register, visit conference.bizchiefs.com/Execution2022.

Yokogawa opens technology center in Baton Rouge

Yokogawa Corp. of America, specializing in industrial automation, opened a technology center in Baton Rouge.

Several dozen people will work from the office, 3895 O’Neal Lane, which will also serve as a local hub for engineers and sales personnel serving area customers.

Tokyo-based Yokogawa has customers in a variety of industries, including energy, chemicals, materials, pharmaceuticals and food.

Georgia-Pacific’s Port Hudson Plant Wins EPA Energy Star Award

Georgia-Pacific’s Port Hudson plant was named Energy Star Challenge Achiever for Industry by the EPA for its efforts to reduce energy consumption.

The facility has voluntarily reduced its energy consumption by 18.5% between 2020 and 2022.

This was accomplished by reducing water, electricity and compressed air consumption, combined with the installation of a more efficient natural gas boiler. The energy reduction will result in annual savings of approximately $8 million.

LSU’s Faculty of Engineering Receives Funding from the U.S. Department of Defense

Two LSU College of Engineering professors — electrical and computer engineering professor Shuangqing Wei and chemical engineering associate professor Kevin McPeak — each recently received grants from the US Army Combat Capabilities Development Command’s Army Research Laboratory.

Wei was awarded $288,579 for his proposal, “Advanced Signal and Information Processing for Interference Management in Radio Communication Systems.” Specifically, the funding enables Wei to obtain instruments that will be used to build a hard-wired, integrated test system/platform on which multiple types of complex interference signals and signals of interest, or SOIs, can be generated and tested in a controlled environment.

McPeak’s proposal, “Thin Film Ellipsometry for Mid-Infrared Optoelectronics,” received $225,000 in funding, which will provide him with two vital pieces of equipment.

“Mid-infrared wavelengths are a very important area for the Department of Defense,” McPeak said. “Being able to detect light in this region is essential for several security applications in the defense sector. There aren’t many materials that absorb electromagnetic radiation in this region that are also able to effectively convert the radiation into an electrical signal.”

FranU Adds Medical-Legal Certificate to Program for Fall 2022

Franciscan Missionaries of Our Lady University has added a Forensic Science Certificate for Fall 2022, which helps pave the way to careers in most areas of crime labs such as drug analysis, toxicology, latents, firearms and receipt of evidence.

The Forensic Science Certificate is designed to create quality educational experiences in forensic science and train highly skilled professionals ready to enter the workforce.

When accompanied by a Bachelor of Science degree in the natural sciences, the certificate ensures that basic educational requirements are met for employment in various forensic fields.

The United States Bureau of Labor Statistics reported that the job outlook for forensic science technicians is positive, with 16% or 2,700 additional jobs expected to be added over the next 10 years.

Admission requirements include enrolling in or obtaining a bachelor’s or graduate degree in chemical sciences, physical sciences, biological sciences, or forensic sciences.

After completing the first six hours of biology and six hours of organic chemistry, students should be able to complete the remaining requirements within one year.

Purchases made through links on our site may earn us an affiliate commission

TechNite 2022 awards prizes | Business premises

A celebration of the region’s booming tech sector recently brought together more than 300 people at the Roanoke-Blacksburg Technology Council annual TechNite party.

Keynote Speakers John Newby, Advocacy Group CEO Organic Virginiaand Conaway Haskins, Vice President of the Crown Corporation Virginia Innovation Partnership Societysaid the region has distinguished itself as a model of collaboration between diverse specialties and communities.

“You have all done an amazing job, especially uniting in Roanoke, Blacksburg, Lynchburg and the New River Valley. The ecosystem here really forms an identity around entrepreneurship and innovation,” Haskins said, adding that the region has skilfully rejected cookie-cutter strategies in favor of developing a vision to term around its unique resources and assets.

These strengths include the expansion of biotechnology research that takes place in facilities such as the Fralin Biomedical Research Institute at VTC, said Heywood Fralin, who was recognized as the guest of honor at the event. Fralin was a key advocate for the state-of-the-art research facility that was founded in 2010 and debuted with a 2020 addition of 139,000 square feet.

People also read…

In that time, Fralin said, the institute grew from an idea with a single employee to a bustling center with more than 35 research teams, employing more than 450 people and pursuing projects collectively worth $180 million. of dollars.

The facility is well positioned, with the continued support of the community, to continue to generate well-paying jobs and inject new money back into the local economy, Fralin concluded.

“I think we’ve only seen the tip of the iceberg,” he said. “We have the best of the best.”

Technite, held on May 19 at Taubman Art Museum, also included the presentation of awards recognizing excellence in the technology community. Winners included:

RBTC HALL OF FAME&underline> : hailed as a “serial entrepreneur and innovator”, Chorda Pharma CEO Victor Iannello, an MIT graduate, has a track record that includes founding several companies, including Radiant physics, which has developed breakthrough products in the energy, industrial technology and healthcare sectors. His current business is a booming pharmaceutical company developing a line of drugs that can manage pain without opioids.

STEM-H EDUCATOR AWARD&underline> : Kathleen O’Dell became a math teacher at Christiansburg Middle School about 15 years ago and is known for incorporating real-world experiences into her curriculum. She became chair of the school’s math department and was named the 2022 Montgomery County Public School Teacher of the Year.

RISING STAR AWARD&underline> : Ticketing, in just two years, has grown its business to reach 1.4 million unique users and process 2.7 million transactions. The company has created a free digital ticketing platform for schools, districts and associations.

INNOVATOR AWARD&underline> : Dr. Robert Gourdie, an entrepreneur, was involved in the creation of three start-up companies doing cutting-edge research. Two of these projects small freight company and Acomhal Research, are on the verge of innovating in the delivery of drugs and the treatment of glioblastoma. Tiny Cargo was one of five companies to receive a Washington, DC, QuickFire Challenge grant of $50,000 to support its work developing a new drug delivery method using nanocapsules derived from cow’s milk. Gourdie’s third startup, First String Researchis in the midst of three active clinical trials.

REGIONAL LEADERSHIP AWARD&underline> : Wendi Pannell, Vice President of Content Production at Ozmo, has been hailed as “a connector of people and ideas”. Pannell has been dedicated to expanding the WoTech program, which supports women in technology.

CONTRACTOR AWARD&underline> : Martin Angst, co-founder of To return, has raised over $730,000 on Kickstarter to support the development of the emerging office robotics company’s first handheld laser cutter. Innovation is poised to dramatically improve access to rapid prototyping and digital manufacturing. More information about this can be found online at launch.rendyr.com.

LEADING TECHNOLOGY COMPANY&underline> : P1 technologies has built a reputation for high standards in one of the most regulated and demanding industries in the market. The company creates wiring and injection molding products with services that include custom specialty designs. The Roanoke County facility focuses on three primary service lines – preclinical medical, audio and in vivo research.

RUBY AWARD&underline> : Kathy Claytor, Vice President of Human Resources for Delta Dental, has been instrumental in working to “build the region’s brand as a destination for top talent, a real necessity for a sustainable and sustainable workforce”, organizers said. Claytor also currently sits on the executive committee of RBTC.

Contact Alicia Petska at alicia.petska@roanoke.com

Manufacturing facilities in Spokane and the Seattle area; deals, financing and more – GeekWire

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The Allen Institute Human Immune System Explorer. In this application, different types of immune cells are grouped according to their gene activity. (Image courtesy of the Allen Institute)

Here’s a look at some of the top life sciences and health news in the Pacific Northwest this week.

Read on for these headlines and more life sciences news from the Pacific Northwest.

– Sana Biotechnology will build a manufacturing plant in the Seattle area, leaving California

– Allen Institute and Google team up to create a platform exploring the immune system

— Gates Foundation-backed Seattle biotech startup launches trial for snail fever vaccine

– Seattle’s Cambia Grove Healthcare Innovation Center Changes Name to Health Policy Center

– ProfoundBio, Led by Seagen Veterans, Raises $70M

The glymphatic system cleanses the brain during sleep and is featured this week in several media outlets. The system is shown here in a mouse brain. (Image by Jeffrey Iliff)

Offers and financing:

  • Jubilant HollisterStier signed a $149.6 million contract with the U.S. government to expand capacity at its Spokane-based facility, which supports manufacturing of COVID-19 vaccines and therapies.
  • Immatics, a German-Houstonian cell therapy company signed an agreement with Bristol Myers Squibb, which founded its cell therapy and immuno-oncology center in Seattle. The two companies will partner to develop two “off the shelf” cell therapies.
  • Washington Research Foundation reward Seattle Children’s researcher Shannon Oda a $250,000 marketing grant to improve T-cell therapies. FRM also promised $1 million to the Buerk Center for Entrepreneurship at UW.
  • Amazon Web Services donated over a million dollars server time at UW’s Institute for Protein Design to train the institution’s RoseTTAFold software, which predicts the three-dimensional shape of proteins.

Technical movements:

Podcasts and posts:

  • The Brain Electrophysiology Laboratory in Eugene, Oregon was featured by Oregon Public Broadcasting and The Washington Post. The lab is developing a headband to improve sleep, previously also highlighted by GeekWire.
  • Lea Starita, researcher at the Brotman Baty Institute has been presented in a podcast featuring his work on human genetic variation.
  • Short documentary by Seattle-area high school student Pinyu Liao about antibiotic resistance was accepted at the World Health Organization Film Festival.
  • The Institute for Health Metrics highlighted its international data on gun violence, showing how the United States is an outlier.
  • Computational science of nature speak with Sean Gibbons, a researcher at the Institute for Systems Biology, talks about his three undergraduate degrees, his work on the microbiome, and his advice to young LGBTQIA+ scientists.
  • Arna Ionescu, CEO of Wavely Diagnostics explained how advances in smartphone technology and changes in healthcare delivery models have enabled his business, which “couldn’t have existed two years ago.” Wavely develops an application to detect ear infections.

3 Cathie Wood stocks that could offer monster returns

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2022 has been brutal for start-up biotech companies. At Cathie Wood’s Ark Genomic Revolution ETF is down 60% from last year. However, Wood’s long-term performance is outstanding, even after this huge drop. Some of its stocks have become much cheaper in the short term. But the upside potential remains huge.

Our roundtable group dug through their holdings and found three stocks that we particularly like. Here’s why we’re optimistic 10x Genomics (NASDAQ:TXG), Beam Therapy (NASDAQ: BEAM) and Recurrence Pharmaceuticals (NASDAQ: RXRX).

Image source: Getty Images.

A leader in a $15 billion market

Patrick Bafuma (10x Genomics): If you browse the holdings of Ark Invest, you will see many moon shots. And every once in a while, you find businesses that are already generating sales. 10x Genomics fits this mold, guiding full-year 2022 revenue of $600-630 million, representing 22%-28% growth over full-year 2021 revenue. half a billion in revenue, this life sciences company is still in the early stages of growth.

This cutting-edge instrument maker sells the machines and associated consumables that enable scientists to look in and around an individual cell, a scientific subspecialty called space biology. This method provides researchers with information at unprecedented resolutions. The company’s tools are already installed in the world’s top 100 research institutes, proving that its product line is essential for today’s research. Scientists must use the 10x toolset or risk being overtaken by their competitors. The company’s strategy of enabling as many researchers as possible to become regular users of its tools is working, having found that customers who own its instruments consistently increase their usage over time. This situation leads to an increase in sales of 10x Genomics high-margin consumables. Sound familiar? This razor and blade model is similar to how Illuminated (NASDAQ: ILMN) has become a monster for shareholders over the past two decades.

This Cathie Wood darling has plenty of leads in the $60 billion-a-year addressable market of life science tools. 10x estimates that $15 billion of that is spent on the space biology research field it already dominates. The field is essentially a one-horse race, with no other space biology research tools used in half as many publications as 10x Genomics tools. It is clear that this instrument manufacturer is the market leader in this emerging field of space biology. And with a steady cadence of new product launches, I think this life sciences company has the best chance of all of Wood’s biotech companies to generate monster returns.

A possible home run stock trading at a steep discount

George Budwell (Beam Therapy): Cathie Wood’s Ark invest has been a shareholder in precision genetic medicine company Beam Therapeutics since the fourth quarter of 2020, according to Whalewisdom. Now, in that roughly two-year holding period, Beam’s stock has appreciated nearly 40%, which is certainly a respectable rate of return for such a short holding period. That said, shares of the precision genetic medicine company have also fallen 73% since hitting an all-time high less than a year ago, in July 2021.

What has weighed on this biotech stock over the past year? The good news is that Beam’s business plan has not encountered any major setbacks. On the contrary, market sentiment has turned extremely sour against start-up research and development companies like Beam.

Why might this sharp pullback be a compelling buying opportunity? Beam’s main selling point to investors is that its proprietary base-editing technology could be a premier platform for developing functional cures for dozens of diseases. So, in theory, Beam could dominate many high-value markets, such as rare blood diseases, inherited genetic disorders, and perhaps some cancers. This is a tremendous business opportunity for a company with a market capitalization of less than $3 billion at the time of this writing.

What is the main downside risk for this stock? Precision gene editing, as a field, is still in its infancy. Additionally, several companies are trying to commercialize their unique gene-editing platforms. Simply put, there’s no way to reliably handicap which of these companies will take gold, so to speak. That doesn’t mean Beam’s equity isn’t worth a shot. But investors shouldn’t overdo it with this speculative gene-editing game either.

Using AI to Rethink Drug Discovery

Taylor Carmichael (Recursion Pharmaceuticals): One of the frightening aspects of investing in drug development is the high failure rate: 90% of potential drugs fail to make it out of clinical trials. How can we improve this success rate?

Recursion has a radical idea. What if we abandoned the “hypothetical” model of drug development? Traditionally, to find new drugs, a scientist had an idea and then tried to confirm it. And if we approached a disease without hypothesis? Instead, we would visually map the cell data and then look at what the data tells us. This could improve the success rate.

That’s what Recursion does. Recursion’s software produced 14 petabytes of biological and chemical images. (It’s estimated that one petabyte contains enough information to fill 20 million workbooks, or about 500 billion sheets of paper.) Using this data, Recursion’s artificial intelligence (AI) performs more than 2 million experiences every week.

This approach results in both faster and cheaper drug discovery. On average, Big Pharma spends about $22 million to find a drug ready for clinical development, and that process takes about two and a half years. Recursion spends $7 million to find a similar drug, and it takes about 10 months.

Unsurprisingly, Big Pharma took notice. rock (OTC: RHHBY) and Bayer (OTC: BAYR.Y) are now collaborating with Recursion. And upfront payments go up. Recursion received $80 million in 2020 and $230 million last year. And future milestone payments are growing: $1 billion in potential milestone payments in 2020 have grown to $13 billion today.

It’s still early days, and in this risk-averse market, the stock has really been beaten. It’s down 75% from last year. But the economic news has actually been strong. Recursion now has several drugs in clinical trials. And it’s sitting on about $600 million in cash, about half of its market capitalization. If the company reports positive test data later this year, the stock will rally dramatically. Risk-tolerant investors might want to open a small position now.

10 stocks we like better than 10x Genomics
When our award-winning team of analysts have stock advice, it can pay to listen. After all, the newsletter they’ve been putting out for over a decade, Motley Fool Equity Advisortripled the market.*

They just revealed what they think are the ten best stocks investors can buy right now…and 10x Genomics wasn’t one of them! That’s right – they think these 10 stocks are even better buys.

View all 10 stocks

* Portfolio Advisor Returns as of June 2, 2022

George Budwell has no position in the stocks mentioned. Patrick Bafuma holds positions in 10x Genomics. Taylor Carmichael has no position in the stocks mentioned. The Motley Fool holds positions and recommends 10x Genomics. The Motley Fool recommends Beam Therapeutics and Illumina. The Motley Fool has a disclosure policy.

The views and opinions expressed herein are the views and opinions of the author and do not necessarily reflect those of Nasdaq, Inc.

Photos: Blue Origin NS-21 Space Tourism Mission

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Blue Origin’s fifth manned spaceflight, a mission called NS-21, is scheduled to launch from the company’s site in West Texas on June 4, 2022.

On NS-21, Blue Origin’s New Shepard vehicle will carry six people – Katya Echazarreta, Victor Correa Hespanha, Jaison Robinson, Victor Vescovo, Hamish Harding and Evan Dick – to suborbital space and back.

Echazarreta, 26, will become the first woman born in Mexico and the youngest American to reach space. Dick would become the very first New Shepard crew member to repeat; it also participated in the NS-19 mission, launched in December 2021.

You can read more about the six passengers in our NS-21 crew member story. And you can see photos of the spaceflyers and their mission here in this gallery.

Related: Blue Origin’s NS-21 mission (reference)

Many thanks from Snapshot Wisconsin

Today, we say thank you to everyone who helped classify wildlife photos on snapshotwisconsin.org. Over the past four years, you’ve helped scientists model species distributions, measure vegetation phenology, study how deer use habitats to escape extreme temperatures, and much more. Below is a partial list of scientific publications to which your work has contributed since 2019.

A curious elk investigates a Snapshot Wisconsin trail camera near Wisconsin’s Clam Lake.

Even though its partnership with NASA is coming to an end, Snapshot Wisconsin shows no signs of slowing down! Volunteers from Snapshot Wisconsin set up and monitor trail cameras, which take photos of passing wildlife. With more than 2,000 cameras deployed and counting, these photos contribute to an extensive database that helps the Wisconsin Department of Natural Resources make wildlife management decisions. Volunteers receive trail cameras and check them every few months. Over 63 million photos have been collected to date! After uploading the images, volunteers join a community around the world to classify by consensus the animals found in the photos. Anyone, anywhere can help categorize photos here at Snapshot Wisconsin. Learn more about getting your own trail camera here: https://dnr.wisconsin.gov/topic/research/projects/snapshot.

Study how deer use habitats to escape extreme temperatures
Gilbert, NA, JL Stenglein, TR Van Deelen, PA Townsend, and B. Zuckerberg. 2022. Behavioral flexibility facilitates the use of spatial and temporal refuges during extreme winter weather. Behavioral ecology, arab154.

As a model for future ecological monitoring
Townsend, PA, JDJ Clare, N. Liu, JL Stenglein, CM Anhalt-Depies, TR Van Deelen, NA Gilbert, A. Singh, KJ Martin, and B. Zuckerberg. 2021. Snapshot Wisconsin: Networking Community Scientists and Remote Sensing to Improve Ecological Monitoring and Management. Ecological applications 31(8): e02436

Modeling of species distributions, integrated with existing data streams (hunter harvest records)
Gilbert, NA, BS Pease, CM Anhalt-Depies, JDJ Clare, JL Stenglein, PA Townsend, TR Van Deelen, and B. Zuckerberg. 2021. Integration of catch and camera trap data into species distribution models. Biological Conservation 258:109147.

Measure vegetation phenology from “bycatch” data from photos
Liu, N., M. Garcia, A. Singh, JDJ Clare, JL Stenglein, B. Zuckerberg, EL Kruger, and PA Townsend. 2021. Trail camera networks provide satellite-derived phenology information for ecological studies. International Journal of Applied Earth Observations and Geoinformation 97:102291

Advancing the science of abundance estimation using camera trap data
Gilbert, NA, JD Clare, JL Stenglein, and B. Zuckerberg. 2021. Estimated abundance of unmarked animals based on camera trap data. Conservation Biology 35(1): 88-100

Assess privacy and data management issues for large-scale citizen science data flows
Anhalt-Depies, C., JL Stenglein, B. Zuckerberg, PM Townsend, and AR Rissman. 2019. Trade-offs and Tools for Data Quality, Privacy, Transparency and Trust in Citizen Science. Biological Conservation 3238: 108195.

Plan citizen science surveys
CM Locke, CM Anhalt-Depies, S. Frett, JL Stenglein, S. Cameron, V. Malleshappa, T. Peltier, B. Zuckerberg and PA Townsend. 2019. Managing a large citizen science project to monitor wildlife. Bulletin of the Wildlife Society, 43: 4-10.

NASA Citizen Science Program:
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Lung Surfactant Market Size, Scope and Forecast

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New Jersey, United States – The Pulmonary Surfactant Market The report is an output of extensive and expert research on the Pulmonary Surfactant industry. Pulmonary Surfactant Market report explains what the market is about, market prognosis, several segmentations and all things related to the market. It also examines the primary and secondary market drivers, market share, potential sales volume, regional analysis and key market segments. The research also includes key variables that contribute to market growth as well as elements that could stifle market growth. VM Reports professionals applied precise research techniques and other analysis.

PESTLE analysis and SWOT analysis are two of the analyzes used in the Pulmonary Surfactant market research, and they shed light on numerous internal and external variables that affect the market in every situation. It also includes a section that identifies strengths, weaknesses, opportunities, and threats, as well as Porter’s five forces model.

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Key Players Mentioned in the Pulmonary Surfactants Market Research Report:

Boehringer Ingelheim, AbbVie, Lyomark Pharma, Tekzima (Noargen), ONY Biotech, Abbott, Aviva Systems Biology, LSBio, Biomatik, Biorbyt, Reddot Biotech, XpressBio, Creative Diagnostics, Nanjing Norris Pharm Technology, Windtree Therapeutics, others.

Lung Surfactant Market Segmentation:

Pulmonary Surfactants Market, By Type

• Synthetic lung surfactants
• Surfactants of animal origin

Pulmonary Surfactants Market, By Application

• Hospital
• Laboratory
• Others

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Scope of Pulmonary Surfactant Market Report

ATTRIBUTES DETAILS
ESTIMATED YEAR 2022
YEAR OF REFERENCE 2021
FORECAST YEAR 2029
HISTORICAL YEAR 2020
UNITY Value (million USD/billion)
SECTORS COVERED Types, applications, end users, and more.
REPORT COVER Revenue Forecast, Business Ranking, Competitive Landscape, Growth Factors and Trends
BY REGION North America, Europe, Asia-Pacific, Latin America, Middle East and Africa
CUSTOMIZATION SCOPE Free report customization (equivalent to up to 4 analyst business days) with purchase. Added or changed country, region and segment scope.

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1. Who are the top five players in the Lung Surfactant market?

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3. Which product and which application will take the lion’s share of the pulmonary surfactants market?

4. What are the drivers and restraints of the Lung Surfactant Market?

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6. What will be the CAGR and size of the Pulmonary Surfactant market throughout the forecast period?

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Job as Lecturer or Associate Professor in Biochemistry and Pharmacology at UNIVERSITY OF MELBOURNE

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Location: Parcville

Role type: Full time / Continuous

Faculty: Faculty of Medicine, Dentistry and Health Sciences

Department/School: Department of Biochemistry and Pharmacology

Salary: Level C ($135,032 – $155,698) OR Level D ($162,590 – $179,123) no more 17% super

Founded in 1853, the University of Melbourne is Australia’s No. 1 university and is consistently ranked among the top universities in the world. We are proud of our staff, our commitment to excellence in research and teaching, and our global engagement.

About the Department of Biochemistry and Pharmacology

The Department of Biochemistry and Pharmacology is committed to developing the careers and well-being of our students and staff, fostering a culture that helps us all do our best. We are guided by our values ​​in our pursuit of excellence. The Department of Biochemistry and Pharmacology has critical mass, interdisciplinary teaching, and remarkable breadth and depth in research expertise that underpin our key themes of molecular understanding of biology and disease, translational research, of drug discovery and development. Our researchers are strongly committed to high-impact discovery research and translating breakthroughs into societal outcomes when the opportunity arises.

The Department of Biochemistry and Pharmacology is strongly committed to supporting diversity and the representation of women. In accordance with Special Measure H103/2014 under Section 12 of the Equal Opportunities Act 2010 (VIC), the Department of Biochemistry and Pharmacology strongly encourages suitably qualified female applicants. We intend that at least one of the two appointees be a woman.

About the role

We have two positions available as a senior lecturer or associate professor, who will develop and maintain a high-level research program in an area of ​​pharmacology complementary to the department’s existing research areas. You will be encouraged to contribute to interdisciplinary research within the School of Biomedical Sciences and the Faculty of Medicine, Dentistry and Health Sciences and the wider academic community. You will also join a successful team in delivering and supporting teaching and learning in pharmacology and therapeutics within the Department and wider School of Biomedical Sciences.

In a typical week at work, you can:

  • Make a meaningful contribution to the delivery of educational programs in the form of lectures, tutorials, workshops and hands-on classes.
  • Lead a successful independent research group that attracts extramural research funds and generates results recognized externally for excellence
  • Apply contemporary pedagogical knowledge to teaching practice, including discipline-specific ones.
  • Make independent and original contributions to program development and evaluation, particularly using online delivery methods.

About you

You are a confident communicator with a demonstrable proactive reflective teaching practice. Your highly developed interpersonal skills allow you to work collaboratively with internal and external colleagues, and you are passionate about mentoring and supporting young researchers in their academic trajectory.

Ideally, you will also have:

  • PhD or in a relevant field or equivalent professional qualification
  • Demonstrated experience in independent and team pharmacological research
  • National-level research profile and emerging international recognition, as evidenced by success in research funding, number of publications, industry interactions, patenting of discoveries, and other metrics of peer recognition.
  • Expertise either in: pharmacokinetics and toxicology; pharmacogenomics; computational approaches to pharmacology and drug design

Benefits of working with us

In addition to having the opportunity to grow and meet challenges, and to be part of a vibrant campus life, our employees enjoy a range of rewarding benefits:

  • Flexible work arrangements and generous personal, parental and cultural leaves
  • Competitive remuneration, 17% super, salary package and leave loading
  • Free and subsidized health and wellness services, and access to fitness and cultural clubs
  • Discounts on a wide range of products and services, including Myki and Qantas Club cards
  • Career development opportunities and 25% off graduate courses for staff and their immediate families

Learn more at https://about.unimelb.edu.au/careers/staff-benefits.

Be yourself

At UoM, we value the unique backgrounds, experiences and contributions each person brings to our community, and we encourage and celebrate diversity. Indigenous Australians, those who identify as LGBTQIA+, women, people of all ages, disabilities or from diverse cultural backgrounds are encouraged to apply for our roles. Our goal is to create a workforce that reflects the community in which we live.

Join us!

If you think this role is right for you, please submit your application, including a brief cover letter, your resume, and your responses to the selection criteria^ (found in the job description) for the role.

^For information to help you compile short statements to meet the selection criteria and competencies, please see http://about.unimelb.edu.au/careers/selection-criteria

If you require reasonable adjustments with the recruitment process, please contact the Talent Acquisition team at hr-talent@unimelb.edu.au.

Due to the impacts of COVID-19, we are currently prioritizing applicants with valid work rights in Australia and applicants who are not affected by travel restrictions. Please see the latest updates to Australia’s immigration and border arrangements: https://covid19.homeaffairs.gov.au/

The University of Melbourne is required to comply with applicable health guidelines and directives issued by the Victorian Minister of Health. The University of Melbourne requires all University of Melbourne employees to be fully immunized against COVID-19 unless an exemption order applies. All applicants must therefore meet this requirement when submitting an application.

Job description: Lecturer, Associate Professor PD.docx

Closing of applications: JUNE 30, 2022 11:55 PM AUS Eastern Standard Time

Researchers examine salmon habitat above Enloe Dam – Methow Valley News

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Photo by Marcy Stamper
About 70 people came to listen to scientists who studied salmon habitat in the Similkameen River and analyzed sediments collected behind the Enloe Dam.

Will analyze the sediment behind the dam for toxins

Tens of thousands of endangered salmon could gain access to high-quality habitat in the Similkameen River watershed if the Enloe Dam were removed, but any dam demolition project would need to address arsenic contamination in the sediment collected behind the dam under deep gravel.

At a community meeting on Enloe Dam in Tonasket last week, federal, state, and tribal biologists and hydrologists, along with representatives of the Colville Tribes, presented findings from preliminary sediment analysis and potential for rainbow trout and spring chinook to reach habitat in British Columbia. The presentation also included a tribal perspective on the Similkameen River and the regional watershed.

With extremely low return rates to the Okanogan watershed in recent years – only 87 adults of native origin have survived this year – “The importance of removing Enloe Dam is probably the only chance that these animals have to survive,” said Colville Confederate Tribes biologist Chris Fisher. .

Fish habitat research and sediment sampling have intensified over the past three years, since the Okanogan County Utility District (PUD), owner of Enloe Dam, decided in 2018 that “It was not cost effective to re-energize the dam for power generation,” Fisher said.

As people wonder what to do with the dam, which hasn’t generated electricity for more than 60 years, questions have been piling up about what’s in the sediment, how much it would cost to remove the dam and clean up the toxins, and who would pay for it, Fisher told the 70 people who came to learn about Enloe. The PUD was asked to provide an update on the dam safety inspections they conducted, but declined, Fisher said. A PUD commissioner attended the presentation, he said.

It’s too early to say what it would cost to remove the dam, as it would depend on the nature of the contamination and how to deal with it safely, according to the presentation.

Sediment analysis

There are about 2.8 million cubic meters of sediment behind Enloe Dam, an amount that would fill 294,000 truckloads of cement, said Andrew Spanjer, a hydrologist with the US Geological Survey (USGS).

The USGS began collecting silt, clay, and sand sediment samples from various depths in the river in 2019. They obtained more than 100 samples in total, including material in the river bed under gravel and cobbles, where the oldest sediments were deposited, Spanjer said. There was concern about the potential for contamination due to mining upstream of the dam in the late 19th and early 20th centuries.

The USGS analyzed the samples for 54 trace elements and metals, including copper, arsenic and mercury, all of which can be toxic at high levels. They did not find high concentrations of copper, cadmium, lead or zinc. The mercury was well below the level that would cause concern and require a cleanup, Spanjer said.

But arsenic concentrations in a third of fine sediment samples — especially in deeper areas — exceed the toxicity threshold, Spanjer said. Fine sediment represents a small fraction of the total sediment retained behind the dam. Most of the coarser material samples did not have high concentrations of arsenic, he said.

Despite the high arsenic levels, the fine sediment is so deep and under so much clean gravel that it does not enter the Similkameen River system, meaning fish and people are protected, Arthur Buchan said. , a Washington Department of Ecology toxicologist. There is no concern unless the material is disturbed, he said. Ecology began its own sampling upstream and downstream of the dam late last year.

Ecology not only examines what is in the sediment, but also whether contaminants bind to the sediment or leach into the surrounding soils. This analysis will help determine if they would need to take any action to prevent sediment from moving downstream if the dam were removed. If contaminants bind to sediment, it would be easier to remove them safely, Buchan said.

In addition to examining contaminants from historic mining, researchers are monitoring the impacts of active mining upstream of the dam in Canada, Spanjer said. They expect the data to be available in 2023.

Moving expenses

There are still too many unknowns for a good estimate of what it would cost to remove Enloe. Depending on whether some or all of the sediment could be spilled onto adjacent land — or just allowed to flow downstream — dam removal could cost anywhere from $51 million to $3.3 million, Mike Brunfelt said. , fluvial geomorphologist at Inter-Fluve, a company that specializes in the restoration of rivers and which has participated in the removal of approximately 200 dams.

Brunfelt’s estimates were based on the assumption that the sediments are clean and safe and would not need to be transported to a special disposal site. If contaminated, costs could increase five to 10 times, Spanjer said. According to biologists, allowing this volume of sediment, even if clean, to enter the river system would present its own problems for the river and the fish.

Potential habitat

About 1,520 miles of the total 3,420 miles in B.C.’s upper Similkameen watershed are accessible to fish, said National Oceanic and Atmospheric Administration fisheries biologist Morgan Bond. There are six routes above Similkameen Falls that chinook and rainbow trout could take to reach upper habitat, Bond said.

Canadian habitat could support 3.9 million chinook salmon in the spring and 9.8 million rainbow trout in the parr stage, during which young salmon are adapting to the river in preparation for their journey to the south. ‘ocean. The upper watershed also provides good habitat for spawning grounds, where salmon lay their eggs. It would support 77,863 chinook spawning grounds and 203,310 rainbow trout spawning grounds, Bond said.

While survival rates for salmon returning from the ocean to their natal river to spawn may seem grim – less than 1% of upper Columbia salmon typically return – this still translates to between 7,800 and 47,000 spring adult salmon. and 29,000 to 118,000 rainbow trout, Bond said. Steelhead is stronger and more athletic than the Chinook spring and therefore generally more efficient at traversing falls, Brunfelt said.

Two members of Aboriginal Outfitters shared a cultural perspective on the river. The nonprofit was established last year to raise awareness of the importance of land stewardship for a community that felt disconnected from the river, said Joy Abrahamson, chief executive of Aboriginal Outfitters. . Water and its central role in sustaining life has always been at the heart of indigenous peoples, who maintain sacred rituals to protect water from pollution, drought and waste, she said.

The Colville Tribes voted to remove the dam in 2017. The Upper and Lower Similkameen Bands in British Columbia also support the removal of the dam.

The Washington Department of Fish and Wildlife is analyzing the biological, management, and legal issues associated with the potential removal of the dam and the restoration of the Similkameen River through a reserve in the state budget . Their findings must be submitted to the Legislative Assembly by December 1.

A video of the presentation will be available online. The link will be on the Methow Valley News website once it is posted.

Ighg1Protein Market Recovers From Covid-19 Outbreak – More Details on Key Players and Future Analysis | Aviva Systems Biology Corporation (USA), St John\’s Laboratory Ltd (UK), Genetex (USA)

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The global Ighg1Protein industry research report provides an in-depth and methodical assessment of regional and global markets, along with the most recent service and product innovations and projected global market size. Ighg1Protein research performs a comprehensive analysis of the market to find major vendors integrating all relevant products and services to understand the roles of key industry players in the Ighg1Protein segment. The Global Ighg1Protein Market also provides an in-depth analysis of cutting-edge competitor research and new industry advancements along with market dynamics, challenges, restraints, and opportunities to give accurate insights and the latest scenarios for appropriate judgments.

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60 UK companies will hold trials four days a week

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Sixty UK businesses will carry out a six-month trial of a four-day working week to help businesses cut working hours without cutting wages or sacrificing revenue.

Such trials have been conducted in Spain, Iceland, the United States and Canada and are expected to take place in Australia and New Zealand in August.

According to Alex Soojung-Kim Pang, program manager of 4 Day Week Global, the campaign organization behind the trial, it will give companies more time to overcome difficulties, experiment with new processes and collect data. .

According to Pang, smaller companies should find it easier to adapt because they can more easily make big changes.

Pressure Drop, which is located in Tottenham Hale, hopes the trial will not only improve their employees’ productivity, but also their well-being.

This will also help reduce their carbon footprint.

Another trial participant, the Royal Society of Biology, said it wanted to give staff “greater authority over their time and work routines”.

The two expect a shortened working week to help them retain staff at a time when UK businesses are facing major labor shortages and a record 1.3 million workers. ‘Jobs.

Unilever was able to experiment with a shortened working week for its 81 workers in New Zealand because there is no production at the Auckland office and all employees work in sales or marketing.

The service industry is vital to the UK economy, accounting for 80% of the country’s GDP.

However, this is more difficult in sectors such as retail, food and beverage, healthcare and education.

The most difficult task will be figuring out how to quantify productivity, especially in an economy where most work is qualitative rather than quantitative.

Sonic workers flee large snake found behind fryer – NBC10 Philadelphia

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Workers cooking burgers and tater tots at a Georgia Sonic fast food kitchen fled after discovering an intruder hiding behind the fryer.

Brunswick Police Lt. Matthew Wilson found Sonic Drive-In employees crowded in the parking lot when he arrived to investigate last Saturday. Over the phone, they had described the culprit as dark-haired with diamonds on his back.

“When I saw it I could tell it was just a ball python and not a rattlesnake,” Wilson told The Brunswick News.

He not only removed the large, non-venomous snake, but also found him a new home with a friend who has a large terrarium and a fondness for snakes.

Wilson says the python likely snuck into the Sonic’s kitchen on May 21 through an open back door, finding a comfortable spot for its cold-blooded body behind the hot fryer.

Police don’t know where the snake came from, although Wilson says it was likely a pet that was released by its owner.

Eammon Leonard agreed. He is an invasive species biologist with the Georgia Department of Natural Resources. Leonard said snakes are often an impulse buy, and owners find themselves having second thoughts as their scaly pets get older.

“It could be that someone just didn’t think about the consequences of having a big snake as a pet,” Leonard said. “Some people have regrets later and just release things. It’s definitely irresponsible. »

Upconversion-based nanosensor developed for the detection of chemotherapy drugs

Figure 1. Portable detection platform for visual quantitative monitoring of mesna. 1 credit

As an important regional antidote to protect the urinary system of chemotherapy patients, mesna (a drug given with chemotherapy to reduce bleeding in the bladder) must be monitored in real time to ensure a curative effect. The fluorescence method is a powerful tool for real-time detection, with the advantages of rapid response and visualization. However, background interference limits its application in biological sensing.

To solve this problem, a research team led by Professor Jiang Changlong of the Hefei Institutes of Physical Sciences (HFIPS) of the Chinese Academy of Sciences (CAS) recently proposed a new method for visual mesna detection. The results were published in Analytical Chemistry.

In this study, researchers visually monitored quantitative mesna in real time with a newly developed wearable sensing platform including an upconversion-based nanosensor.

The nanosensor was constructed by upconverting nanoparticles (UCNPs) and ethyl violet (EV), in which UCNPs acted as donors and EVs as quenchers.

The addition of mesna caused the fluorescent and colorimetric chromaticity variations, realizing the dual-read function of the nanosensor. Benefiting from the upconversion luminescence excited by near infrared rays, the background interference of biological samples was eliminated and effectively improved the sensitivity of detection. The lower limit of detection (LOD) of the nanosensor was as low as 26 and 48 nM for fluorescence and colorimetric signals, respectively.

Upconversion-based nanosensor developed for the detection of chemotherapy drugs

Figure 2. RGB analysis of upconversion luminescence using a smartphone. 1 credit

Additionally, a highly compatible portable detection platform was designed for easy detection of mesna with a detection limit of 56 nM.

The nanosensor has good selectivity and anti-interference ability and shows good reliability in actual sample detection.

The platform can be developed as a point-of-care testing application for real-time monitoring of mesna levels to guide dose adjustments and therapeutic efficacy. It provides a simple and reliable strategy for clinical drug monitoring and presents potential application perspectives.


Luminescent sensors developed for the highly sensitive detection of semicarbazide and heparin


More information:
Bin Hu et al, A portable sensing platform using an upconversion-based nanosensor for visual quantitative monitoring of Mesna, Analytical Chemistry (2022). DOI: 10.1021/acs.analchem.2c00380

Provided by Chinese Academy of Sciences

Quote: Upconversion Based Nanosensor Developed for Chemotherapy Drug Detection (2022, May 30) Retrieved May 30, 2022 from https://phys.org/news/2022-05-upconversion-based-nanosensor-chemotherapy-drug .html

This document is subject to copyright. Except for fair use for purposes of private study or research, no part may be reproduced without written permission. The content is provided for information only.

Pulmonary Surfactant Market Size and Forecast to 2029

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New Jersey, United States – Current trends, industry analysis and growth development exemplified in this “Pulmonary Surfactant Market” report are very beneficial for newbies entering the market. This report covers the whole scenario which is driving the growth of the market, including factors such as challenges, drivers, recent trends, restraints, technological advancements as well as opportunities for players. This market performs a perfect assessment of the market to provide a complete overview of the market development with reference to the future projections and the market scenario. This analytical research on Pulmonary Surfactants Market share, industry volume and growth aspects.

This Pulmonary Surfactant Market report covers latest events, trade restrictions, customs analysis, stakeholder management, value chain efficiency, sales growth, influence of local and international players industry and outlook. Evolution of revenue generation, regulatory changes, competitive industry growth studies, company size, categorization of industry growths, industry specializations and supremacy, l Risk assessment, marketing strategies, regional developments, and technological innovations in the market are all aspects considered in this Lung Surfactant market. report as well as a COVID-19 analysis on each sector.

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Key Players Mentioned in the Pulmonary Surfactants Market Research Report:

Boehringer Ingelheim, AbbVie, Lyomark Pharma, Tekzima (Noargen), ONY Biotech, Abbott, Aviva Systems Biology, LSBio, Biomatik, Biorbyt, Reddot Biotech, XpressBio, Creative Diagnostics, Nanjing Norris Pharm Technology, Windtree Therapeutics, others.

Lung Surfactant Market Segmentation:

Pulmonary Surfactants Market, By Type

• Synthetic lung surfactants
• Surfactants of animal origin

Pulmonary Surfactants Market, By Application

• Hospital
• Laboratory
• Others

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Scope of Pulmonary Surfactant Market Report

ATTRIBUTES DETAILS
ESTIMATED YEAR 2022
YEAR OF REFERENCE 2021
FORECAST YEAR 2029
HISTORICAL YEAR 2020
UNITY Value (million USD/billion)
SECTORS COVERED Types, applications, end users, and more.
REPORT COVER Revenue Forecast, Business Ranking, Competitive Landscape, Growth Factors and Trends
BY REGION North America, Europe, Asia-Pacific, Latin America, Middle East and Africa
CUSTOMIZATION SCOPE Free report customization (equivalent to up to 4 analyst business days) with purchase. Added or changed country, region and segment scope.

Answers to key questions in the report:

1. Who are the top five players in the Pulmonary Surfactant market?

2. How will the Pulmonary Surfactant Market grow in the next Five years?

3. Which product and which application will take the lion’s share of the pulmonary surfactants market?

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Verified Market Research® is a leading global research and advisory firm that for over 10 years has provided advanced analytical research solutions, personalized advice and in-depth data analysis to individuals and businesses seeking accurate research, reliable and up to date. data and technical advice. We provide insight into strategic and growth analytics, the data needed to achieve business goals, and help make critical revenue decisions.

Our research studies help our clients make superior data-driven decisions, understand market forecasts, capitalize on future opportunities, and maximize efficiency by working as a partner to deliver accurate and valuable insights. The industries we cover span a wide spectrum, including technology, chemicals, manufacturing, energy, food and beverage, automotive, robotics, packaging, construction, mining and the gas. Etc.

At Verified Market Research, we help in understanding holistic market indicator factors and most current and future market trends. Our analysts, with their deep expertise in data collection and governance, use industry techniques to gather and review data at all stages. They are trained to combine modern data collection techniques, superior research methodology, subject matter expertise and years of collective experience to produce informative and accurate research.

Having served over 5000 clients, we have provided reliable market research services to over 100 Global Fortune 500 companies such as Amazon, Dell, IBM, Shell, Exxon Mobil, General Electric, Siemens, Microsoft, Sony and Hitachi. We have co-consulted with some of the world’s leading consulting firms such as McKinsey & Company, Boston Consulting Group, Bain and Company for custom research and consulting projects for companies around the world.

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UK businesses to test four-day working week

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Similar trials have also taken place in Spain, Iceland, the United States and Canada.

London, United Kingdom:

Louis Bloomsfield inspects beer kegs at his north London brewery, looking forward to June when he will have an extra day off every week.

The 36-year-old brewer plans to use this time to get involved in charity work, start a long-awaited particle physics course and spend more time with his family.

He and his colleagues at the Pressure Drop brewery are taking part in a six-month trial of a four-day working week, along with 3,000 other people from 60 UK companies.

The pilot project – touted as the largest in the world to date – aims to help businesses cut working hours without cutting wages or sacrificing revenue.

Similar trials have also taken place in Spain, Iceland, the United States and Canada. Australia and New Zealand are expected to start theirs in August.

Alex Soojung-Kim Pang, program manager at 4 Day Week Global, the campaign group behind the trial, said it would give companies “more time” to tackle challenges, experiment with new practices and collect data.

Small organizations should find it easier to adapt because they can make big changes more easily, he told AFP.

Pressure Drop, based in Tottenham Hale, hopes the experience will not only improve the productivity of its employees, but also their well-being.

At the same time, it will reduce their carbon footprint.

The Royal Society of Biology, another participant in the trial, says it wants to give employees “more autonomy over their time and their work rhythms”.

The two hope a shorter working week could help them retain employees, at a time when UK businesses are facing severe staff shortages and vacancies hitting a record 1.3million.

Not all pink

Brewery Pressure Drop co-founder Sam Smith said the new way of working would be a learning process.

“It will be difficult for a business like ours that has to operate constantly, but that’s what we’re going to experience in this trial,” he said.

Smith is considering giving his employees different days off during the week and splitting them into two shifts to keep the brewery running.

When Unilever trialled a shorter working week for its 81 employees in New Zealand, it was only able to do so because no manufacturing takes place in its Auckland office and all staff work in sales or marketing.

The service industry plays a huge role in the UK economy, contributing 80% of the country’s GDP.

A shorter workweek is therefore easier to adopt, said Jonathan Boys, a labor economist at the Chartered Institute of Personnel and Development.

But for sectors such as retail, food and beverage, healthcare and education, it is more problematic.

The boys said the biggest challenge will be how to measure productivity, especially in an economy where a lot of work is qualitative, as opposed to that of a factory.

Indeed, since the wages will remain the same in this trial, for a company not to be a loser, the employees will have to be as productive in four days as in five.

Yet Aidan Harper, author of “The Case for a Four Day Week,” said countries that work fewer hours tend to have higher productivity.

“Denmark, Sweden, the Netherlands work fewer hours than the UK but have higher levels of productivity,” he told AFP.

“In Europe, Greece works more hours than anyone else, yet it has the lowest levels of productivity.”

“Recruiting a Superpower”

Employees in the UK work around 36.5 hours a week, compared to their Greek counterparts who work more than 40 hours, according to database firm Statista.

Phil McParlane, founder of Glasgow-based recruitment firm 4dayweek.io, says offering a shorter working week is a win-win solution, and even calls it “a hiring superpower”.

His company only offers four-day weekly jobs and flex jobs.

They have seen the number of companies looking to hire through the platform jump from 30 to 120 over the past two years, as many workers reconsidered their priorities and work-life balance amid the pandemic.

(This story has not been edited by NDTV staff and is auto-generated from a syndicated feed.)

In the news

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• Andrea Steinebach says her family is ‘still haunted by the illegal invasion of our home in the middle of the night by the very people who are supposed to protect us’ as a judge orders St. Louis County to pay $300,000 after police burst in with guns drawn in search of a suspect who had skipped the taxi fare.

• Lesli Myers-Small, Superintendent of Schools in Rochester, NY, said she was “horrified” as several teachers were furloughed and could be fired after exchanging text messages making racist and demeaning references to students.

• Shannon LaFargue, academic director of Calcasieu Parish, Louisiana, was named superintendent by an 8-7 vote and said the mission “tries to be flexible, gives teachers real autonomy, gives teachers the opportunity to say, “I can have fun today in this class. “”

• Montana Superintendent of Schools Elsie Arntzen has been ticketed and is heading to city court after being charged with overtaking a school bus in a van while stopped to pick up students from a residential development.

• Tracy Wolff, pastor of Pitts Chapel United Methodist Church in Springfield, Mo., says ‘it’s not just tagging…it was a hate crime’ as police investigate the painting of a swastika on a historically black church that becomes “one of the most diverse places in town.”

• Marquetta Curry, a former Georgia state employee, was charged with attempting to steal $60,000 from two elderly women, asking one to give her a blank check and trying to cash it another check telling the bank that she was the victim’s great-niece. .

• Curt Kemmerer, a wildlife biologist for the Iowa Department of Natural Resources, conceded that “perhaps three to five bears” live statewide, as a “bear aware” press release reported was released after a number of sightings in Dubuque.

• Jacqueline Nunez, a Boston developer, said ‘this is not a real estate development; it’s around my own beliefs’ as her company paid $1.525 million for the 18th-century Rhode Island farmhouse that has inspired the 2013 film “The Conjuring”, saying she ‘I’m going to keep it open like a paranormal business.

• Diana DiZoglio, a Massachusetts lawmaker, said at least the state ‘could set the record straight’ as lawmakers exonerated Elizabeth Johnson Jr., clearing her name after she was convicted of witchcraft in 1693 at the height of the Salem Witch Trials, although she was not executed.

Meera Komarraju: Advancing Human Knowledge: SIU Carbondale’s College of Agricultural, Life and Physical Sciences is at the Forefront | Education

Science is a constant process of asking questions and seeking answers – an endeavor pursued with passion by the faculty, staff and students of the College of Agricultural, Life and Physical Sciences (CALPS).

Answering big questions

CALPS faculty are awarded an abundance of highly competitive grants each year that provide funds to explore answers to questions facing society. From feeding the world to curing cancer, from pushing the boundaries with drone technologies to developing new fuels, materials and beyond, it’s all being researched right here in Southern Illinois through of CALPS.

The grant revenue generated supports both graduate and undergraduate students who are trained to answer these questions for themselves. Our highly accomplished faculty has been recognized by numerous awards from national and international organizations.

Student Opportunities

Formed just under two years ago, CALPS comprises six schools, including Agricultural Sciences, Biological Sciences, Chemical and Biomolecular Sciences, Earth Systems and Sustainability, Forestry and Horticulture, and Physics and applied physics. These schools prepare students for bachelor’s, master’s and doctoral degrees as well as certificates.

People also read…

The Institute of Fermentation Sciences and University Farms provide experiential learning opportunities for students, and the Medical School offers the popular BS degree in Physiology through CALPS. Students enhance their education by gaining practical skills by actively engaging in undergraduate research, presentation, and publication opportunities and by being involved in their areas of interest. By hosting events like the Registered Student Organizations Fair and the Fall BBQ, we create a community atmosphere for our students, faculty, and staff.

Community involvement

In addition to formal education, CALPS outreach efforts bring agriculture and science to schoolchildren and the public.

Each summer, field days at our farms allow interested members of the community to discover the research that engages and fascinates our faculty. The sustainable farm holds summer workshops on vegetable planting, flower arranging and other topics, and sells fresh produce from our gardens.

We are delighted to host events accompanying major events such as the 2017 Solar Eclipse and are preparing for the 2024 Solar Eclipse in Carbondale. We regularly host STEM University for Scouts, youth fishing events, attend regional and national science fairs, and have thousands of FFA students on campus each year – and love collaborating with our many community stakeholders to promote agriculture, life and physical sciences.

Science and agriculture are closely linked and rapidly changing in our modern world. CALPS faculty, staff, and students continue to bring new opportunities to Southern Illinois. It’s an exciting journey, and we invite members of the Southern Illinois community to join us!

Meera Komarraju is president and vice chancellor for academic affairs at Southern Illinois University Carbondale.

Zymergen Sells Octant-Scale Modular Automation System

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EMERYVILLE, Calif., May 26, 2022 (GLOBE NEWSWIRE) — Zymergen Inc. (“Zymergen” or the “Company”), today announced that it has entered into an agreement with Octant for the sale of a modular automation system to Octant’s scale next-generation platform for developing breakthrough drugs.

Zymergen’s comprehensive automation solution includes modular hardware, modern web-based software, custom and turnkey workflows, and active monitoring and support. This technology will be integrated with Octant’s existing platform which uses synthetic biology, high-throughput multiplexed assays, synthetic chemistry and computation to design and interrogate drugs, proteins and signaling pathways. During this multi-phase partnership, the two companies will work together to expand Octant’s platform, enable new automated workflows and increase throughput as instruments are added to the scalable system.

“Octant is a leading therapeutic company focused on developing drugs that match the complexity of human disease,” said Sri Kosuri, Co-Founder and CEO of Octant. “Zymergen is a key partner in helping us move this effort forward. Zymergen’s automation technology will accelerate our ability to create drugs with novel mechanisms of action guided by massive datasets in engineered human cells. These datasets provide insight into genetics, chemistry, biochemical function, and disease phenotypes. Technology will help us accelerate and scale our development of life-changing drugs and therapies for some of the world’s most challenging diseases. »

“At Zymergen, having built and operated our own large-scale in-house automation system for years, we have a unique and insightful view of the challenges that must be solved to fully automate, maintain, scale and reconfigure such a system,” Zymergen said. Acting CEO, Jay Flatley. “Our technology supports the flexibility, throughput and precision demanded by Octant’s rapidly evolving therapeutic platform. We are thrilled to partner with their team and look forward to expanding the business potential of our automation technology with other customers. »

The initial installation consists of 5 reconfigurable automation carts with plans to expand over time as Octant adapts its workflows. Additional terms of the agreement were not disclosed. This is Zymergen’s first customer agreement since the company announced the commercialization of its high-performance automation systems earlier this year.

About Zymergen Automation Technology

Zymergen’s automation technology is designed to improve the throughput, efficiency and reliability of laboratory operations. It is based on building blocks called Reconfigurable Automation Carts, or RACs, which house task-focused instruments such as liquid handlers and analytical devices. RACs are easily connected to form a raceway that moves plates from station to station and can be remotely controlled by Zymergen’s cloud software that schedules workflows, monitors progress, and collects scientific data , process and instrument performance. A RAC system can scale to different sizes depending on throughput and application, and can be reconfigured in hours. To learn more, visit zymergen.com/automation.

About Zymergen

Zymergen is a biotechnology company that designs and produces molecules, microbes and materials for various end markets. We partner with nature to make better products, a better way, for a better world. For more information, visit www.zymergen.com.

About Octant

Octant is a next-generation therapeutics company integrating novel and large-scale experimental technologies (multiplexed measurements and high-throughput synthetic chemistry) with computations to solve complex drug discovery challenges. Octant designs drugs with novel mechanisms of action guided by large, proprietary datasets in engineered human cells that provide insight into genomes, drug candidates, biochemical function and disease phenotypes. The Octant platform uses synthetic biology, high-throughput multiplexed assays, synthetic chemistry and computation to engineer and interrogate drugs, proteins and cellular pathways at unprecedented scales. For more information, visit www.octant.bio.

Forward-looking statements

This press release contains “forward-looking statements” within the meaning of the Private Securities Litigation Reform Act of 1995, as amended. These forward-looking statements are based on the beliefs and assumptions of the Company and on the information currently available to it as of the date of this press release. In some cases, you can identify these statements by forward-looking words such as “may”, “will”, “continue”, “anticipate”, “intend”, “could”, “plan”, “will”. expect” or the negative or plural of these similar words or expressions. Forward-looking statements in this press release include, but are not limited to, statements regarding the customer pipeline for our automation business, the potential benefits of our automation technology and services to our customers, and our expectations for future improvement and expansion of our automation technology. and services for our customers. Forward-looking statements may involve known and unknown risks, uncertainties and other factors that may cause the Company’s actual results, performance or achievements to be materially different from those expressed or implied by the forward-looking statements, including, but not limited to, risks relating to the Company’s ability to attract and retain automation customers and to provide and develop its automation technology and services for its customers. These and other risks are described in more detail in the Company’s filings with the Securities and Exchange Commission, including the Company’s Quarterly Report on Form 10-Q for the quarter ended March 31, 2022, and other documents that the Company subsequently files with the SEC. Except to the extent required by law, the Company undertakes no obligation to update these statements to reflect events that occur or circumstances that exist after the date on which they were made.

Zymergen Investor Contact
investors@zymergen.com

Octant, Inc. Media Contacts
press@octant.bio

Norway sacks the board of its research council for financial mismanagement | New

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The Norwegian Ministry of Education and Research has sacked all 12 board members of its research council over serious allegations of financial mismanagement.

The Forskningsrådet agency, which funds the country’s research projects, has also been ordered to stop giving grants for now in areas likely to decline. The board was replaced by a new chair – Kristin Halvorsen, Norway’s former finance minister and education minister – and just four other members. They will supervise the agency until the end of the year and will launch an external evaluation of its finances.

Forskningsrådet has admitted he will be short 275m Norwegian kroner (£23m) this year. This deficit is expected to reach NOK 1.9 billion next year and NOK 2.9 billion in 2024 if no measures are taken to limit spending.

More money has been pledged than the research council, said the country’s science and higher education minister, Ola Borten Moe. In recent years, the research council has received just under NOK 11 billion per year. Its economic problems are not due to the government allocating less money to research, Borten Moe pointed out. Rather, they are the result of a lack of control and management.

The events have caused concern and unrest among Norwegian researchers. “Hard to understand this as anything other than a complete disaster for the Norwegian people,” tweeted Curt Rice, president of the Norwegian University of Life Sciences.

Nils Charles Prieur, hydrologist and planetary scientist at University of Oslo, complained that the Norwegian government has failed to recognize the possible repercussions of freezing new calls for research grants for the rest of the year. He said 90% of postdoctoral students and researchers in the country only have two-year contracts, so the potential stoppage of funds for six months poses a “significant hurdle”..

Siri Birkeland, an evolutionary biologist at the Norwegian University of Life Sciences, was about to apply for a research stay abroad when Forskningsrådet abruptly closed the call for proposals. “They don’t even know what will happen to the applications they have already received,” she tweeted. According to the result, Birkeland suggestedthe ministry’s actions could end up costing him a year’s salary and overseas research experience.

Acidic oceans could drastically reduce one of the world’s largest oxygen producers

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The tiny floating organisms that provide our world with up to a fifth of its oxygen will be in dire straits as our oceans acidify, new research suggests.

The creatures, called diatoms, will be deprived of the silica building blocks they need to build their protective shells, which come in all sorts of dazzling opaline forms.

This could reduce their numbers by up to 26% by the end of the next century, researchers have found.

“Diatoms are one of the most important plankton groups in the ocean,” says marine biologist Jan Taucher of the GEOMAR Helmholtz Center for Ocean Research Kiel (GEOMAR).

“Their decline could result in a significant change to the marine food web or even a change to the ocean as a carbon sink.”

These single-celled algae make up 40% of the photosynthetic biomass in the ocean, making them one of the main components of the biological pump that absorbs CO2 out of our atmosphere, storing it in the depths of the ocean.

They are one of the reasons why the oceans have managed to absorb much of the excess CO2 we humans produce.

(Samarpita Basu/Katherine RM Mackey/Wiki/CC BY-SA 4.0)

Above: Role of phytoplankton in the biological carbon pump.

But as our excess CO2 dissolves in seawater, it reacts to form more hydrogen ions, increasing the acidity of the water. This altered ocean chemistry has already resulted in a 10% decrease in carbonate concentrations since industrialization.

Less carbonate means it is harder for calcium carbonate to form; it is a vital molecule for most marine animals as it is part of their shells and exoskeletons.

If the carbonate concentration drops too low, the calcium carbonate dissolves. Some animals now experience the dissolution of their shell.

In contrast, it was thought that diatoms, which build their complex glass houses out of completely different materials, would be relatively unaffected by ocean acidification and might even benefit from increased CO2.

These phytoplankton build their outer shells, called frustules, from the silica that floats in the surface waters of the ocean.

But the new research identifies a factor that has been missed by previous studies. It turns out that as the pH of the water drops, these vital silica elements will start to dissolve more slowly, which means more of it will sink deeper into the depths of the ocean. before it becomes light enough to stay afloat.

This leads to more silica at the bottom of the ocean, well out of reach of diatoms floating in the light which they use to transform CO2 in oxygen, water and carbohydrates, which hinders their ability to build their frustule homes.

Incredible detail of an opalized silica frustule under 1500x magnification.An opaline silica frustule under 1500x magnification. (Massimo brizzi/Wikipedia/CC BY-SA 4.0)

Taucher and his fellow researchers discovered this by using giant ocean “test tubes” (mesocosms), where they added different concentrations of CO2 to simulate future warming scenarios.

They then assessed samples from different depths – analyzing the sediments filled with dead diatoms that they captured. This, together with modelling, supported by previous studies of the silica chemistry of diatoms, revealed a staggering decline in floating silica, suggesting diatoms could decline by up to a quarter by 2200.

Such a huge loss of these phytoplankton will have dramatic ramifications for other life forms on our planet, given that these organisms are one of the primary primary producers of the ocean.

“[A]The associated consequences on ecosystem functioning and the carbon cycle are more difficult to assess,” the team states in their paper, explaining that they failed to take into account many physiological and ecological processes that could trigger an effect. domino over the rest of the food web.

Either way, the results show how unexpected feedback mechanisms in Earth systems can radically alter environmental and biological changes that we may think we understand – revealing that we still have a lot to learn about how our planet works. and its life forms are intertwined.

“This study highlights once again the complexity of the Earth system and the associated difficulty in predicting the consequences of human-induced climate change in its entirety,” says GEOMAR marine biologist Ulf Riebesell.

“Surprises like this remind us again and again of the incalculable risks we face if we don’t tackle climate change quickly and decisively.”

This research was published in Nature.

MSU Orientation Officials Welcome New Students to Campus Starting Next Week

Contact: Cammie Hopkins

MSU Orientation leaders welcoming new students to campus this summer include (front row, left to right): Carrington Davis, Nathan Mosley, Vyusti Yadav, Grace Breuers and Jamarcus Sutton; (second row, left to right) Omega Storey, Madison Beckham, Sara Frances Wolfe, Raegan Rushing, Camila Salazar and Anna Schumacher; (third row, left to right) Emily Shand, Dehn Basham, Trey O’Neal, Tim Boyd and Titus Neyland; (back row, left to right) Jacob Carter, Obuchi Aga and Kelan Traylor. (Photo submitted)

STARKVILLE, Miss.—Mississippi State recognizes 19 students from Mississippi, Alabama, Tennessee, North Carolina, Texas and India who are leading the university’s orientation programs beginning next week.

In conjunction with the Office of Orientation and Events, MSU Orientation Officers provide assistance and share knowledge about the 144-year-old land-grant institution with incoming freshmen and college students. transfers – and their families – during each of the many information and registrations of the school year. sessions.

Selected from nearly 60 nominees, Guidance Leaders go through a rigorous selection process to earn this distinction. In preparation for orientation sessions and events, these leaders complete a focused course that prepares them to welcome new members of the Bulldog family to campus.

Students who have served this year include (by hometown):

BILOXI—Raegan Rushing, an industrial engineering major.

BYRAM—Jamarcus Sutton, a marketing and psychology major.

CANTON—Jacob Carter, communications graduate.

COLLIERVILLE, Tennessee—Dehn Basham, graduate in landscape architecture.

COLUMBIA, Tennessee—Emily Shand, junior industrial engineering student.

COLUMBUS—Carrington Davis, a junior primary education major.

DECATUR, Alabama—Grace Breuers, a marketing major.

FORT WORTH, Texas—Anna Schumacher, junior communications student.

GURGAON, India—Vyusti Yadav, junior in business administration and finance.

JACKSON—Titus Neyland, Computer Science graduate.

NETTLETON—Trey O’Neal, software engineering graduate.

RIPLEY—Omega Storey, a junior primary education major.

SALISBURY, North Carolina—Timothy Boyd, graduate in biological sciences.

SOUTHAVEN—Madison Beckham, graduate in educational psychology.

STARKVILLE—Camila Salazar, a biomedical engineering major.

TERRY—Obuchi Aga, a marketing major.

TUPELO—Kelan Traylor, a communications major; and Sara Frances Wolfe, a biochemistry major.

VICKSBURG—Nathan Mosley, junior graduate in biomedical engineering.

To learn more about this summer’s orientation sessions and to register, visit MSU’s Office of Admissions and Scholarships at admissions.msstate.edu/enrollment.

MSU is the main university in Mississippi, available online at www.msstate.edu.

Protein Polymer Hydrogel Market Size and Forecast

New Jersey, United States – Protein Polymer Hydrogel Market The 2022-2029 report has been prepared based on an in-depth market analysis with input from industry experts. The Polymer Protein Hydrogel Market study sheds light on the significant growth momentum that is anticipated to prevail during the assessment period 2022-2029. The study offers statistics on key segments in important geographies, along with detailed mapping of the global competitive landscape. Additionally, the market report tracks the global sales of Polymeric Protein Hydrogel in 25+ high growth markets, while analyzing the impact COVID-19 has had on the current industry and the Polymeric Protein Hydrogel sector in particular.

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Top Key Players in Polymer Protein Hydrogel Market Research Report:

Cardinal Health, Gecko Biomedical, Gelita Medical AG, GluStitch, Grifols International, Hemostasis, HyperBranch Medical Technology, InnoTherapy, Marine Polymer Technologies, MedTrade Products, Meyer-Haake, Ocular Therapeutix, OptMed

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Protein Polymer Hydrogel Market – Type Outlook (Revenue, USD Million, 2017-2029)

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ATTRIBUTES DETAILS
ESTIMATED YEAR 2022
YEAR OF REFERENCE 2021
FORECAST YEAR 2029
HISTORICAL YEAR 2020
UNITY Value (million USD/billion)
SECTORS COVERED Types, applications, end users, and more.
REPORT COVER Revenue Forecast, Business Ranking, Competitive Landscape, Growth Factors and Trends
BY REGION North America, Europe, Asia-Pacific, Latin America, Middle East and Africa
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➛ North America (United States, Canada and Mexico)
➛ Europe (Germany, France, United Kingdom, Russia and Italy)
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CHST15 Antibody Market Growth, Market Size, Share with Top Key Players like R&D Systems (US), Novus Biologicals (US), Abcam (UK), Boster Biological Technology (US), Thermo Fisher Scientific (USA), etc.

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chst15 antibody market

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Some of the major manufacturers operating in this market include: R&D Systems (USA), Novus Biologicals (USA), Abcam (UK), Boster Biological Technology (USA), Thermo Fisher Scientific (USA), Santa Cruz Biotechnology (USA), RayBiotech (US), Origene (US), Lifespan Biosciences (US), USBiological (US), Proteintech (US), Genetex (US), Biobyt (UK), Aviva Systems Biology Corporation (USA), Fitzgerald Industries International (USA), Atlas Antibodies (SE), Abbexa Ltd (UK), Bio-Rad (USA), Bioss Antibodies (USA), St John’s Laboratory Ltd (UK) and more…

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Market segmentation by type: Above 90% Above 95% Above 99% OtherMarket Segment by Application: Biopharmaceutical companies Hospitals Bioscience research institutions Other

Regions Covered in Global CHST15 Antibody Market:1. South America The CHST15 antibody market covers Colombia, Brazil and Argentina.2. North America The CHST15 antibody market covers Canada, the United States and Mexico.3. Europe The CHST15 antibody market covers UK, France, Italy, Germany and Russia.4. The Middle East and Africa The CHST15 antibody market covers UAE, Saudi Arabia, Egypt, Nigeria and South Africa.5. Asia Pacific The CHST15 antibody market covers Korea, Japan, China, Southeast Asia and India.Years considered to estimate the market size:Historical year: 2015-2022Year of reference : 2022Estimated year: 2022Forecast year: 2022-2028

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  • Chapter 5: Production volume, price, gross margin and revenue ($) of CHST15 antibody by regions.
  • Chapter 6: Production, Consumption, Export and Import of CHST15 Antibodies by Regions.
  • Chapter 7: CHST15 Antibody Market Status and SWOT Analysis by Regions.
  • Chapter 8: Competitive landscape, product introduction, company profiles, market distribution status by CHST15 Antibody players.
  • Chapter 9: CHST15 Antibody Market Analysis and Forecast by Type and Application.
  • Chapter 10: CHST15 Antibody Market Analysis and Forecast by Regions.
  • Chapter 11: CHST15 Antibody industry characteristics, key factors, new entrants SWOT analysis, investment feasibility analysis.
  • Chapter 12: CHST15 Antibody Market Conclusion of the whole report.
  • Carry on…

For more information with full table of contents: https://www.globmarketreports.com/industry-reports/242021/chst15-antibody-market

Key Highlights of the CHST15 Antibody Market Report:• Growth Rate • Earnings Forecast • Consumption Graph • Market Concentration Rate • Secondary Industry Competitors • Competitive Structure • Major Constraints • Market Drivers • Regional Bifurcation • Competitive Hierarchy • Current Market Trends • Concentration Analysis of the marketReport customization: Global Market Reports provides customization of reports according to your needs. This report can be customized to meet your needs. Get in touch with our sales team, who will guarantee you get a report tailored to your needs.

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18 skills every child should know, according to the world’s most adventurous parents

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From the time ultrarunner Katie Arnold’s daughters were babies, she and her husband began taking them wilderness rafting with other families. During the safety talk, before putting the rafts in the water, she always took a moment to make it clear that it was about the wilderness, not a gym in the jungle where an accident was that simple than a quick trip to emergency care. She would tell her daughters and other children, “We need you to take care of your body and others.

Arnold, who is also a writer, carefully chose the wording of his directive. “It teaches them autonomy and personal responsibility to take care of themselves, while having that collective mindset that you always need on expeditions – and also in real life – that is, say that we also have to be careful of each other, because if something happens to one of us, it happens to all of us.

Now that his daughters have entered their teens and are getting serious about skiing (both are on their local resort’s ski team), Arnold has enforced the “Ski in Your Body” directive. In other words, “Don’t be in your brain thinking, ‘Who’s going to love it when I try to do this 360? Who’s going to see this tail grab? Ski into your body. If that’s your body saying, ‘Yeah, I want to do this,’ then do it,” says Arnold.

Something the directive does do not say is “be careful”. Which is also intentional on Arnold’s part. “There’s this gender bias where we tell girls to be safe and boys to go,” Arnold says, “and I didn’t want to perpetuate that.” Arnold adopted the directive from her own mantra as a professional runner, “Run in your body.” “It’s a more evolved version of ‘Take care of your body and others,'” she says. “But it’s the same message to stay in your body, to be aware of it. And act accordingly. And I think you can apply that to anything.

Katie Arnold is a professional ultrarunner who has won many of America’s most prestigious races, including the Leadville Trail 100, TransRockies and the Angel Fire 100. She is also an award-winning freelance writer and editor of Outside magazine, where her chronicle “Raising Rippers,” about raising adventurous children, ran from 2011 to 2019. Arnold’s memoir Run home (Random House, 2019) recounts the healing powers of long-distance running in the wake of her father’s death.

Flamingos spawn more often in South Florida

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MIAMI-DADE COUNTY, Florida. – The flamingo has been immortalized in plastic lawn decorations, stylized in logos and appeared in iconic scenes on the big and small screen, like the Miami Vice opening sequence.

Most South Florida residents usually only see the pink bird in captivity.

That is, until recently.

Big Pine Key conservationist and photographer Valerie Preziosi snapped photos of a lone flamingo wading through crystal clear water in January. Before that, she said there were six flamingos spotted in July 2020.

Preziosi said the flock seen two years ago was “split between the Ramrod Salt Flats and Big Torch Keys,” and provided a rare birding experience for residents and birdwatching enthusiasts.

In March, a flamingo and snow goose were spotted at a horse race at Gulfstream Park; the flamingo looked like it had been hit by a horse.

A Gulfstream Park spokesperson said a few flamingos had been spotted in the infield in recent years.

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“There were definitely flamingos in Florida in the 1800s, and unfortunately people were hunting populations here to extinction,” said ZooMiami conservation biologist Dr. Steven Whitfield.

Whitfield said American flamingos were sometimes hunted for food and had their feathers plucked for fashion.

“A lot of people thought the flamingos weren’t native because the history wasn’t clear,” Whitfield said.

So when the birds started appearing, he and his group of scientists wanted to know where they came from.

That’s when they noticed a trio of flamingos near Key West in 2015. After a storm chased two away, a lone bird remained. They named him Conchy.

“Conchy reported to Naval Air Station Key West. We were able to capture Conchy and put a satellite transmitter on her,” Whitfield recalled. “We expected him to go to Cuba or the Bahamas and leave Florida pretty quickly. But he ended up staying for two years.

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Whitfield says her team worked with the Florida Fish and Wildlife Conservation Commission to redesignate flamingos as “native” in 2018, though FWC told Local 10 News that pink birds have always been considered native.

Could flamingos return to the wild?

“It looks like they are, and that’s really encouraging,” Whitfield said. “He’s such an iconic bird for Florida. I think everyone would love to see them back, it’s just a matter of how we do that.

Copyright 2022 by WPLG Local10.com – All rights reserved.

Aerospace and Life Sciences ICT Market 2022 Segment Analysis by Top Key Players: SGS, Element Materials Technology, Eurofins Scientific, Bureau Veritas, MISTRAS, Intertek, ALS Ltd., Applus+, TUV Rheinland, UL

The Global Aerospace and Life Sciences ICT Market: 2022 was recently released by the Mr Accuracy Reports. The report offers a tip on the ICT Market for Aerospace and Life Scienceswhich helps business strategists make the best investment assessment.

The ICT for Aerospace and Life Sciences market industry report includes details of the historical analysis of the ICT for Aerospace and Life Sciences market, which has a timeline from 2017 to 2020. The current state of the ICT for Aerospace and Life Sciences market is also well discussed in the report along with the forecast analysis of the market till 2030. The report begins with the market overview of ICT base for aerospace and life sciences, which includes the market definition, market scope and target audience. In the last section, market dynamics are thoroughly defined which includes market drivers, restraints, opportunities, challenges, market advancements in terms of technology and others.

Some of the Major Key Players profiled in the study are SGS, Element Materials Technology, Eurofins Scientific, Bureau Veritas, MISTRAS, Intertek, ALS Ltd., Applus+, TUV Rheinland, UL

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The Asia-Pacific region is expected to lead the market over the forecast period owing to the growing emphasis on research, development and manufacturing of ICT for aerospace and life sciences in countries such as China, Japan, India and South Korea.

Report objectives:

  • To study the Aerospace and Life Sciences ICT market size based on value and volume.
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  • To analyze key ICT market dynamics for Aerospace and Life Sciences.
  • Discover significant Aerospace and Life Sciences ICT market trends based on revenue, production, and sales.
  • Define the profile of the best players and their status on the global platform
  • Focus on market pricing, product manufacturing, growth drivers and forecast trends.
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  • Estimating the size and market share of all segments, regions and the market.

In addition, the report includes Aerospace and Life Sciences ICT market segment types. The product type and application segments are explained in detail with the help of yearly number and growth rate. The data is represented in the form of tables and images thus allowing a clear understanding of the market scenario. The regional analysis includes data for regions such as North America, Europe, Asia-Pacific, Latin America, Middle East and Africa.

ICT market taxonomy for aerospace and life sciences

Aerospace and Life Sciences ICT Segmentation by Type:

Testing services, inspection services, certification services, other services.

Aerospace and Life Sciences ICT Segmentation by Application:

Aerospace, life sciences

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Market analysis and insights related to COVID-19

  • Due to the outbreak of the COVID-19 virus in December 2020, the pandemic has affected almost all regions of the global platform in terms of human life and economy. The ICT market for aerospace and life sciences has also been impacted by COVID-19.
  • According to the analysis of our research analysts: COVID-19 will affect the economics of the Aerospace and Life Sciences ICT market in three ways. First, by directly affecting production and demand. Second, by creating supply chain and market disruptions and finally, by its financial impact on businesses and financial markets.

How will the ICT for Aerospace and Life Sciences Market report prove useful?

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